Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR: LA-cp rat

Experimental Physiology

Volumn 100, Issue 6, 2015, Pages 730-741

  Fillmore, Natasha ^a   Keung, Wendy ^a   Kelly, Sandra E ^a,b   Proctor, Spencer D ^a,b   Lopaschuk, Gary D ^a,b   Ussher, John R ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CYCLOSERINE; DRINKING WATER; GLUCOSE; INSULIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PYRUVATE DEHYDROGENASE; BIOLOGICAL MARKER; ENZYME INHIBITOR; GLUCOSE BLOOD LEVEL; ISOENZYME; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C LAMBDA; PYRUVATE DEHYDROGENASE COMPLEX; SERINE PALMITOYLTRANSFERASE;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CALORIMETRY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME INHIBITION; FAST MUSCLE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; NONHUMAN; OBESITY; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SLOW MUSCLE FIBER; TREATMENT OUTCOME; WEIGHT GAIN; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECTS; ENERGY METABOLISM; FAST MUSCLE FIBER; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; TIME FACTOR;

ANIMALS; BIOMARKERS; BLOOD GLUCOSE; CERAMIDES; CYCLOSERINE; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; ENZYME INHIBITORS; INSULIN; INSULIN RESISTANCE; ISOENZYMES; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SLOW-TWITCH; OBESITY; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; PYRUVATE DEHYDROGENASE COMPLEX; RATS; SERINE C-PALMITOYLTRANSFERASE; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84930576213     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/EP085052     Document Type: Article

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