Self-assembled betulinic acid protects doxorubicin induced apoptosis followed by reduction of ROS-TNF-α-caspase-3 activity

Biomedicine and Pharmacotherapy

Volumn 72, Issue , 2015, Pages 144-157

  Dash, Sandeep Kumar ^a   Chattopadhyay, Sourav ^a   Ghosh, Totan ^b   Dash, Shib Shankar ^a   Tripathy, Satyajit ^a   Das, Balaram ^a   Bag, Braja Gopal ^a   Das, Debasis ^b   Roy, Somenath ^a  

^a VIDYASAGAR UNIVERSITY   (India)

^b UNIVERSITY OF CALCUTTA   (India)

Author keywords

Apoptosis; Cytotoxicity; DOX; Protective role; Reactive oxygen species; Self assembled betulinic acid

Indexed keywords

BETULIC ACID; CASPASE 3; DOXORUBICIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; INTERLEUKIN 10; INTERLEUKIN 12P70; LACTATE DEHYDROGENASE; MALONALDEHYDE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; PROTECTIVE AGENT; TRITERPENE; TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; BARK; CELL MEMBRANE; CELL SURVIVAL; CELL VIABILITY; CHEMOTHERAPY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DNA BINDING; DRUG MECHANISM; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; JUJUBE; LIPID PEROXIDATION; LYMPHOCYTE PROLIFERATION; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; SCANNING ELECTRON MICROSCOPY; WESTERN BLOTTING; X RAY DIFFRACTION; CELL SHAPE; CHEMISTRY; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; LIGHT RELATED PHENOMENA; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR SHAPE; SYNTHESIS;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL NUCLEUS SHAPE; CELL SHAPE; CELL SURVIVAL; DOXORUBICIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GLUTATHIONE DISULFIDE; HUMANS; INFLAMMATION MEDIATORS; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, SCANNING; OPTICAL PHENOMENA; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA; X-RAY DIFFRACTION;

EID: 84930510989     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2015.04.017     Document Type: Article

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