Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line

Cell Death and Differentiation

Volumn 9, Issue 3, 2002, Pages 252-263

  Armstrong, J S ^a   Steinauer, K K ^a   Hornung, B ^a   Irish, J M ^b   Lecane, P ^b   Birrell, G W ^a   Peehl, D M ^b   Knox, S J ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Apoptosis; GSH; Mitochondria; Reactive oxygen species; Redox

Indexed keywords

BUTHIONINE SULFOXIMINE; CASPASE 3; CASPASE INHIBITOR; CYTOCHROME C; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CELL LEVEL; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSOL; ENZYME DEGRADATION; INCUBATION TIME; LYMPHOMA CELL LINE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BUTHIONINE SULFOXIMINE; CELL CYCLE; CYTOCHROME C GROUP; CYTOSOL; DITHIOTHREITOL; GLUTATHIONE; HUMANS; LYMPHOMA, B-CELL; MEMBRANE POTENTIALS; MITOCHONDRIA; NF-KAPPA B; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036122504     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400959     Document Type: Article

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