Betulinic acid ameliorates endothelium-dependent relaxation in l-NAME-induced hypertensive rats by reducing oxidative stress

European Journal of Pharmaceutical Sciences

Volumn 44, Issue 3, 2011, Pages 385-391

  Fu, Jia Yin ^a   Qian, Ling Bo ^a   Zhu, Lie Gang ^a   Liang, Hao Te ^a   Tan, Yi Nuo ^a   Lu, Han Ti ^a   Lu, Jian Feng ^a   Wang, Hui Ping ^a   Xia, Qiang ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Betulinic acid; Endothelium dependent relaxation; Hypertension; Nitric oxide; Oxidative stress

Indexed keywords

ACETYLCHOLINE; BETULIC ACID; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA, THORACIC; DATA INTERPRETATION, STATISTICAL; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HYPERTENSION; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TRITERPENES; VASODILATION;

EID: 80053900695     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.08.025     Document Type: Article

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