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Volumn 2, Issue 4, 2009, Pages 222-230

Methanol extract of Ocimum gratissimum protects murine peritoneal macrophages from nicotine toxicity by decreasing free radical generation, lipid and protein damage and enhances antioxidant protection

Author keywords

Antioxidants; Free radical; Murine peritoneal macrophage; Nicotine; Ocimum gratissimum

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CATALASE; FLAVONOID; FREE RADICAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MYELOPEROXIDASE; NICOTINE; OCIMUM GRATISSIMUM EXTRACT; PHENOL DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

EID: 70350176895     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.2.4.9000     Document Type: Article
Times cited : (32)

References (60)
  • 1
    • 0036066981 scopus 로고    scopus 로고
    • Validation of traditional claim of tulsi, Ocimum sanctum Linn. as a medicinal plant
    • Gupta SK, Prakash J, Srivastava S. Validation of traditional claim of tulsi, Ocimum sanctum Linn. as a medicinal plant. Ind J Exp Biol 2002; 40:765-73.
    • (2002) Ind J Exp Biol , vol.40 , pp. 765-773
    • Gupta, S.K.1    Prakash, J.2    Srivastava, S.3
  • 3
    • 0022800340 scopus 로고
    • Smoth muscle contracting lipidicsoluble principles in chromatographic fractions of Ocimum gratissimum
    • Onajobi FD. Smoth muscle contracting lipidicsoluble principles in chromatographic fractions of Ocimum gratissimum. J Ethnopharmacol 1986; 18:3-11.
    • (1986) J Ethnopharmacol , vol.18 , pp. 3-11
    • Onajobi, F.D.1
  • 4
    • 0027287948 scopus 로고
    • Antimutagenic activity of extracts of leaves of four common edible vegetable plants in Nigeria (West Africa)
    • Obaseiki-Ebor EE, Odukoya K, Telikepally H, Mitscher LA, Shankel DM. Antimutagenic activity of extracts of leaves of four common edible vegetable plants in Nigeria (West Africa). Mutat Res 1993; 302:109-17.
    • (1993) Mutat Res , vol.302 , pp. 109-117
    • Obaseiki-Ebor, E.E.1    Odukoya, K.2    Telikepally, H.3    Mitscher, L.A.4    Shankel, D.M.5
  • 6
    • 0035860013 scopus 로고    scopus 로고
    • The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil
    • Orafidiya LO, Oyedele AO, Shittu AO, Elujoba AA. The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil. International Journal of Pharmaceutics 2001; 224:177-83.
    • (2001) International Journal of Pharmaceutics , vol.224 , pp. 177-183
    • Orafidiya, L.O.1    Oyedele, A.O.2    Shittu, A.O.3    Elujoba, A.A.4
  • 7
    • 0028787108 scopus 로고
    • Preliminary studies of the antifungal activities of some medical plants against Basidiobolus and some other pathogenic fungi
    • Nwosu MO, Okafor JI. Preliminary studies of the antifungal activities of some medical plants against Basidiobolus and some other pathogenic fungi. Mycoses 1995; 38:191-5.
    • (1995) Mycoses , vol.38 , pp. 191-195
    • Nwosu, M.O.1    Okafor, J.I.2
  • 11
    • 0037121008 scopus 로고    scopus 로고
    • Anthelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus
    • Pessoa LM, Morais SM, Bevilaqua CML, Luciano JHS. Anthelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus. Veterinary Parasitology 2002; 109:59-63.
    • (2002) Veterinary Parasitology , vol.109 , pp. 59-63
    • Pessoa, L.M.1    Morais, S.M.2    Bevilaqua, C.M.L.3    Luciano, J.H.S.4
  • 15
    • 0020460365 scopus 로고
    • Nicotine, resorption and fate
    • Schievelbein H. Nicotine, resorption and fate. Pharm Ther 1982; 18:233-48.
    • (1982) Pharm Ther , vol.18 , pp. 233-248
    • Schievelbein, H.1
  • 17
    • 0032531214 scopus 로고    scopus 로고
    • Nicotine enantiomers and oxidative stress
    • Yildiz D, Ercal N, Armstrong DW. Nicotine enantiomers and oxidative stress. Toxicology 1998; 130:155-65.
    • (1998) Toxicology , vol.130 , pp. 155-165
    • Yildiz, D.1    Ercal, N.2    Armstrong, D.W.3
  • 18
    • 7944234974 scopus 로고    scopus 로고
    • Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer
    • DOI 10.1016/j.mehy.2004.03.048, PII S0306987704003706
    • Kovacic P, Cooksy A. Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer. Medical Hypotheses 2005; 64:104-11. (Pubitemid 39469246)
    • (2005) Medical Hypotheses , vol.64 , Issue.1 , pp. 104-111
    • Kovacic, P.1    Cooksy, A.2
  • 19
    • 58149202134 scopus 로고    scopus 로고
    • Vitro nicotine induced superoxide mediated DNA fragmentation in lymphocytes: Protective role of Andrographis paniculata Nees
    • Das S, Neogy S, Gautam N, Roy S. In vitro nicotine induced superoxide mediated DNA fragmentation in lymphocytes: Protective role of Andrographis paniculata Nees. Toxicol In Vitro 2009; 23:90-8.
    • (2009) Toxicol in Vitro , vol.23 , pp. 90-98
    • Das, S.1    Neogy, S.2    Gautam, N.3    Roy, S.4
  • 20
    • 33645933894 scopus 로고    scopus 로고
    • Protection of lipid peroxidation and carbonyl formation in proteins by capsaicin in human erythrocytes subjected to oxidative stress
    • Luqman S, Rizvi SI. Protection of lipid peroxidation and carbonyl formation in proteins by capsaicin in human erythrocytes subjected to oxidative stress. Phytother Res 2006; 20:303-6.
    • (2006) Phytother Res , vol.20 , pp. 303-306
    • Luqman, S.1    Rizvi, S.I.2
  • 21
    • 37048999963 scopus 로고    scopus 로고
    • Protective effect of quercetin on nicotine-induced prooxidant and antioxidant imbalance and DNA damage in Wistar rats
    • Muthukumaran S, Sudheer AR, Menon VP, Nalini N. Protective effect of quercetin on nicotine-induced prooxidant and antioxidant imbalance and DNA damage in Wistar rats. Toxicol 2008; 243:207-15.
    • (2008) Toxicol , vol.243 , pp. 207-215
    • Muthukumaran, S.1    Sudheer, A.R.2    Menon, V.P.3    Nalini, N.4
  • 22
    • 39549096664 scopus 로고    scopus 로고
    • Amelioratory effect of Andrographis paniculata Nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress
    • Neogy S, Das S, Kar Mahapatra S, Mandal N, Roy S. Amelioratory effect of Andrographis paniculata Nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress. Env Toxicol Pharmacol 2008; 25:321-8.
    • (2008) Env Toxicol Pharmacol , vol.25 , pp. 321-328
    • Neogy, S.1    Das, S.2    Kar Mahapatra, S.3    Mandal, N.4    Roy, S.5
  • 23
    • 34047255787 scopus 로고    scopus 로고
    • Protective effect of ferulic acid on nicotine-induced DNA damage and cellular changes in cultured rat peripheral blood lymphocytes: A comparison with N-acetylcysteine
    • DOI 10.1016/j.tiv.2006.11.006, PII S0887233306002475
    • Sudheer AR, Muthukumaran S, Kalpana C, Srinivasan M, Menon VP. Protective effect of ferulic acid on nicotine-induced DNA damage and cellular changes in cultured rat peripheral blood lymphocytes: A comparison with N-acetylcysteine. Toxicol In Vitro 2007a; 21:576-85. (Pubitemid 46550738)
    • (2007) Toxicology in Vitro , vol.21 , Issue.4 , pp. 576-585
    • Sudheer, A.R.1    Muthukumaran, S.2    Kalpana, C.3    Srinivasan, M.4    Menon, V.P.5
  • 24
    • 33846066790 scopus 로고    scopus 로고
    • Ellagic acid, a natural polyphenol protects rat peripheral blood lymphocytes against nicotine-induced cellular and DNA damage in vitro: With the comparison of N-acetylcysteine
    • DOI 10.1016/j.tox.2006.10.010, PII S0300483X06006147
    • Sudheer AR, Muthukumaran S, Devipriya N, Menon VP. Ellagic acid, a natural polyphenol protects rat peripheral blood lymphocytes against nicotine-induced cellular and DNA damage in vitro: With the comparison of N-acetylcysteine. Toxicol 2007b; 230:11-21. (Pubitemid 46073326)
    • (2007) Toxicology , vol.230 , Issue.1 , pp. 11-21
    • Sudheer, A.R.1    Muthukumaran, S.2    Devipriya, N.3    Menon, V.P.4
  • 26
    • 35948991058 scopus 로고    scopus 로고
    • Oxidative stress in lymphocytes, neutrophils and serum of oral cavity cancer patients: Modulatory array of L-glutamine
    • Das S, Kar Mahapatra S, Gautam N, Das A, Roy S. Oxidative stress in lymphocytes, neutrophils and serum of oral cavity cancer patients: modulatory array of L-glutamine. Support Care Cancer 2007; 15:1399-409.
    • (2007) Support Care Cancer , vol.15 , pp. 1399-1409
    • Das, S.1    Kar Mahapatra, S.2    Gautam, N.3    Das, A.4    Roy, S.5
  • 27
    • 0002878513 scopus 로고
    • Macrophages, antigen-presenting cells, and the phenomena of antigen handling and presentation
    • Paul WE, (Ed.), Raven Press, New York
    • Unanue ER. Macrophages, antigen-presenting cells, and the phenomena of antigen handling and presentation. In Paul WE, (Ed.), Fundamental Immunology, Raven Press, New York 1989; 95-115.
    • (1989) Fundamental Immunology , pp. 95-115
    • Unanue, E.R.1
  • 28
    • 0036257519 scopus 로고    scopus 로고
    • Immune cells redox state from mice with endotoxininduced oxidative stress. Involvement of NFêB Stress
    • Victor MV, De La Fuente M. Immune cells redox state from mice with endotoxininduced oxidative stress. Involvement of NFêB Stress. Free Radical Res 2002; 36:33-45.
    • (2002) Free Radical Res , vol.36 , pp. 33-45
    • Victor, M.V.1    De La Fuente, M.2
  • 30
    • 0033840263 scopus 로고    scopus 로고
    • The role of inflammation in vascular diseases
    • Sullivan GW, Sarembock IJ, Linden J. The role of inflammation in vascular diseases. J Leuk Biol 2000; 67:591-602.
    • (2000) J Leuk Biol , vol.67 , pp. 591-602
    • Sullivan, G.W.1    Sarembock, I.J.2    Linden, J.3
  • 31
    • 10644294503 scopus 로고    scopus 로고
    • Beneficial effect of Hippophase rhamnoides L on nicotine induced oxidative stress in rat blood compared with vitamin e
    • Suleyman H, Gumustakine K, Taysi S, Keles S, Oztasan N, Aktas O, et al. Beneficial effect of Hippophase rhamnoides L on nicotine induced oxidative stress in rat blood compared with vitamin E. Biol Pharm Bull 2002; 25:1133-6.
    • (2002) Biol Pharm Bull , vol.25 , pp. 1133-1136
    • Suleyman, H.1    Gumustakine, K.2    Taysi, S.3    Keles, S.4    Oztasan, N.5    Aktas, O.6
  • 33
    • 0033938716 scopus 로고    scopus 로고
    • Antioxidant effect of onion oil (Allium cepa Linn) on the damages induced by nicotine in rats as compared to alphatocopherol
    • Helen A, Krishnakumar K, Vijayammal PL, Augusti KT. Antioxidant effect of onion oil (Allium cepa Linn) on the damages induced by nicotine in rats as compared to alphatocopherol. Toxicol Lett 2000; 116:61-8.
    • (2000) Toxicol Lett , vol.116 , pp. 61-68
    • Helen, A.1    Krishnakumar, K.2    Vijayammal, P.L.3    Augusti, K.T.4
  • 34
    • 12344261427 scopus 로고    scopus 로고
    • Modulatory effects of curcumin on lipid peroxidation and antioxidant status during nicotine-induced toxicity
    • Kalpana C, Menon VP. Modulatory effects of curcumin on lipid peroxidation and antioxidant status during nicotine-induced toxicity. Pol J Pharmacol 2004; 56:581-6. (Pubitemid 40123658)
    • (2004) Polish Journal of Pharmacology , vol.56 , Issue.5 , pp. 581-586
    • Kalpana, C.1    Menon, V.P.2
  • 35
    • 0028789676 scopus 로고
    • Antioxidants and immune response in aged persons: Overview of present evidence
    • Meydani SN, Wu D, Santos MS, Hayek MG. Antioxidants and immune response in aged persons: overview of present evidence. J Am Clin Nutr 1995; 62:1462-76.
    • (1995) J Am Clin Nutr , vol.62 , pp. 1462-1476
    • Meydani, S.N.1    Wu, D.2    Santos, M.S.3    Hayek, M.G.4
  • 36
    • 33644806615 scopus 로고    scopus 로고
    • Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania sp. against nitrosothiol-induced cytotoxicity
    • Romao PR, Tovar J, Fonseca SG, Moraes RH, Cruz AK, Hothersall JS, et al. Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania sp. against nitrosothiol-induced cytotoxicity. Braz J Med Biol Res 2006; 39:355-63.
    • (2006) Braz J Med Biol Res , vol.39 , pp. 355-363
    • Romao, P.R.1    Tovar, J.2    Fonseca, S.G.3    Moraes, R.H.4    Cruz, A.K.5    Hothersall, J.S.6
  • 37
    • 0028845979 scopus 로고
    • Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues
    • Sarkar S, Yadav P, Trivedi R, Bansal AK, Bhatnagar D. Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues. J Elem Med 1995; 9:144-7.
    • (1995) J Elem Med , vol.9 , pp. 144-147
    • Sarkar, S.1    Yadav, P.2    Trivedi, R.3    Bansal, A.K.4    Bhatnagar, D.5
  • 38
    • 0036845966 scopus 로고    scopus 로고
    • Oxidants, antioxidants and carcinogenesis
    • Ray G, Husain SA. Oxidants, antioxidants and carcinogenesis. Ind J Exp Biol 2002; 42:1213-32.
    • (2002) Ind J Exp Biol , vol.42 , pp. 1213-1232
    • Ray, G.1    Husain, S.A.2
  • 39
    • 0037092508 scopus 로고    scopus 로고
    • Sperm plasmamembrane-associated glutathione S-transferases as gamete recognition molecules
    • Hemachand T, Gopalakrishnan B, Salunke DM, Totey SM, Shaha C. Sperm plasmamembrane-associated glutathione S-transferases as gamete recognition molecules. J Cell Sci 2002; 115:2053-65.
    • (2002) J Cell Sci , vol.115 , pp. 2053-2065
    • Hemachand, T.1    Gopalakrishnan, B.2    Salunke, D.M.3    Totey, S.M.4    Shaha, C.5
  • 40
    • 0036195961 scopus 로고    scopus 로고
    • The phytoestrogen daidzein affects the antioxidant enzyme system of rat hepatoma H4IIE cells
    • Rohrdanz E, OhleTran-Thi RS, Tran-Thi QH, Kahl R. The phytoestrogen daidzein affects the antioxidant enzyme system of rat hepatoma H4IIE cells. J Nutri 2002; 132:370-5.
    • (2002) J Nutri , vol.132 , pp. 370-375
    • Rohrdanz, E.1    Ohletran-Thi, R.S.2    Tran-Thi, Q.H.3    Kahl, R.4
  • 41
    • 0027982195 scopus 로고
    • Reactivity of dietary phenolic acids with peroxyl radicals: Antioxidant activity upon low density lipoprotein peroxidation
    • Laranjinha JAN, Almeida LM, Madeira VM. Reactivity of dietary phenolic acids with peroxyl radicals: antioxidant activity upon low density lipoprotein peroxidation. Biochem Pharmacol 1994; 48:487-94.
    • (1994) Biochem Pharmacol , vol.48 , pp. 487-494
    • Laranjinha, J.A.N.1    Almeida, L.M.2    Madeira, V.M.3
  • 42
    • 0035071213 scopus 로고    scopus 로고
    • Comparison of the effect of lidocaineepinephrine and prilocainefelypressine to alter macrophage functions
    • Azuma Y, Ohura K. Comparison of the effect of lidocaineepinephrine and prilocainefelypressine to alter macrophage functions. Int Immunopharmacol 2001; 1:911-23.
    • (2001) Int Immunopharmacol , vol.1 , pp. 911-923
    • Azuma, Y.1    Ohura, K.2
  • 43
    • 1842503109 scopus 로고    scopus 로고
    • Effect of dietary fat saturation on lipid metabolism, arachidonic acid turnover and peritoneal macrophage oxidative stress in mice
    • Oliveros LB, Videla AM, Gimenez MS. Effect of dietary fat saturation on lipid metabolism, arachidonic acid turnover and peritoneal macrophage oxidative stress in mice. Braz J Med Biol Res 2004; 37:311-20.
    • (2004) Braz J Med Biol Res , vol.37 , pp. 311-320
    • Oliveros, L.B.1    Videla, A.M.2    Gimenez, M.S.3
  • 44
    • 0036758020 scopus 로고    scopus 로고
    • Estimation of total flavonoid content in propolis by two complementary colorimetric methods
    • Chang C, Yang M, Wen H, Chern J. Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J Food Drug Analysis 2002; 10:178-82.
    • (2002) J Food Drug Analysis , vol.10 , pp. 178-182
    • Chang, C.1    Yang, M.2    Wen, H.3    Chern, J.4
  • 46
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 47
    • 0036082232 scopus 로고    scopus 로고
    • Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes
    • Sandhu SK, Kaur G. Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes. Biogerontology 2002; 3:161-73.
    • (2002) Biogerontology , vol.3 , pp. 161-173
    • Sandhu, S.K.1    Kaur, G.2
  • 48
    • 0018095849 scopus 로고
    • Increased superoxide anion production by immunologically activated and chemically elicited macrophages
    • Johnston RB Jr, Godzik CA, Cohn ZA. Increased superoxide anion production by immunologically activated and chemically elicited macrophages. J Exp Med 1978; 148:115-27.
    • (1978) J Exp Med , vol.148 , pp. 115-127
    • Johnston Jr., R.B.1    Godzik, C.A.2    Cohn, Z.A.3
  • 49
    • 0021717404 scopus 로고
    • Activation of a NADPH oxidase from horse polymorphonuclear leukocytes in a cell-free system
    • Heyneman RA, Vercauteren RE. Activation of a NADPH oxidase from horse polymorphonuclear leukocytes in a cell-free system. J Leukoc Biol 1984; 36:751-9.
    • (1984) J Leukoc Biol , vol.36 , pp. 751-759
    • Heyneman, R.A.1    Vercauteren, R.E.2
  • 50
    • 31044434193 scopus 로고
    • Characterization and quantification of the peroxidase in human neutrophils
    • Bos AR, Weaver R, Ross D. Characterization and quantification of the peroxidase in human neutrophils. Biochem Biophys Acta 1990; 525:4133-41.
    • (1990) Biochem Biophys Acta , vol.525 , pp. 4133-4141
    • Bos, A.R.1    Weaver, R.2    Ross, D.3
  • 51
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95:351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 54
    • 0002191974 scopus 로고
    • Catalase
    • Bergmeyer HW, (Ed.), Section 3, Academic Press, New York
    • Luck H. Catalase. In Bergmeyer HW, (Ed.), Methods of Enzymatic Analysis, Section 3, Academic Press, New York 1963; 885-94.
    • (1963) Methods of Enzymatic Analysis , pp. 885-894
    • Luck, H.1
  • 55
    • 0018327389 scopus 로고
    • Levels of glutathione reductase and glutathione-S-transferase activities in rat lung and liver
    • Moron MS, Kepierre JW, Mannervick B. Levels of glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochim Biophys Acta 1979; 582:67-8.
    • (1979) Biochim Biophys Acta , vol.582 , pp. 67-68
    • Moron, M.S.1    Kepierre, J.W.2    Mannervick, B.3
  • 56
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione sulfide using glutathione reductase and 2-Vinyl pyridine
    • Griffith OW. Determination of glutathione and glutathione sulfide using glutathione reductase and 2-Vinyl pyridine. Anal Biochem 1980; 106:207-12.
    • (1980) Anal Biochem , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 57
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70:158-69.
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 59
    • 0016275313 scopus 로고
    • Glutathione-S-transferases. the first enzymatic step in mercapyuric acid formation
    • Habig WH, Pabst MJ, Jakoby WB. Glutathione-S-transferases. The first enzymatic step in mercapyuric acid formation. J Biol Chem 1974; 249:7130-9.
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3


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