Role of mammalian target of rapamycin in hypoxic or ischemic brain injury: Potential neuroprotection and limitations

Reviews in the Neurosciences

Volumn 23, Issue 3, 2012, Pages 279-287

  Chen, Hongju ^a   Qu, Yi ^a   Tang, Binzhi ^a   Xiong, Tao ^a   Mu, Dezhi ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain injury; Hypoxia; Ischemia; Mammalian target of rapamycin; Neuroprotection

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MTOR PROTEIN, HUMAN; NERVE PROTEIN; NEUROPROTECTIVE AGENT; NEUROTOXIN; TARGET OF RAPAMYCIN KINASE;

ANGIOGENESIS; APOPTOSIS; ARTICLE; BRAIN DAMAGE; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL DEATH; CELL SURVIVAL; DISEASE SEVERITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INDUCTION; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; NERVE CELL DEGENERATION; NERVE CELL GROWTH; NERVE CELL PLASTICITY; NERVE REGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; ANIMAL; BIOSYNTHESIS; BIOTRANSFORMATION; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BIOTRANSFORMATION; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE REGENERATION; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEUROPROTECTIVE AGENTS; NEUROTOXINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84867289064     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/revneuro-2012-0001     Document Type: Article

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