Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N- terminal kinase activity in apoptosis of cultured cerebellar granule neurons

Developmental Brain Research

Volumn 112, Issue 2, 1999, Pages 245-253

  Shimoke, Koji ^a   Yamagishi, Satoru ^a   Yamada, Masashi ^a   Ikeuchi, Toshihiko ^a   Hatanaka, Hiroshi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Akt; BDNF; c Jun; High potassium; LY294002

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLOHEXIMIDE; DACTINOMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; POTASSIUM ION; PROTEIN SERINE THREONINE KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REPRESSION; GRANULE CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; RAT; REACTION ANALYSIS; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; CEREBELLUM; CHROMONES; ENZYME INHIBITORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NEURONS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-JUN; RATS;

ANIMALIA;

EID: 0033524740     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(98)00172-2     Document Type: Article

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