The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome

Gut

Volumn 65, Issue 7, 2016, Pages 1087-1099

  Ng, Garrett Z ^a,b   Menheniott, Trevelyan R ^b   Every, Alison L ^a   Stent, Andrew ^a   Judd, Louise M ^b   Chionh, Yok Teng ^a   Dhar, Poshmaal ^a,b   Komen, Jasper C ^b   Giraud, Andrew S ^b   Wang, Timothy C ^c   McGuckin, Michael A ^d   Sutton, Philip ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c Columbia University ^*  (United States)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 1BETA; MUCIN 1; TRANSFORMING GROWTH FACTOR BETA; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 1BETA CONVERTING ENZYME; IRAK4 PROTEIN, MOUSE; NLRP3 PROTEIN, MOUSE; TFF2 PROTEIN, HUMAN; TREFOIL FACTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPIGENETICS; GASTRIC MUCOSA; GENE; HELICOBACTER INFECTION; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; MORTALITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; STOMACH PROTECTION; TFF2 GENE; TISSUE LEVEL; TRANSGENIC MOUSE; WILD TYPE MOUSE; ANIMAL; C57BL MOUSE; COMPLICATION; FEMALE; GASTRITIS; GENE EXPRESSION; GENETICS; HELICOBACTER PYLORI; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MICROBIOLOGY; MONOCYTE; PATHOGENICITY; PATHOLOGY; SIGNAL TRANSDUCTION; STOMACH MUCOSA; TIME FACTOR;

ANIMALS; CASPASE 1; DNA METHYLATION; FEMALE; GASTRIC MUCOSA; GASTRITIS; GENE EXPRESSION; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; INFLAMMASOMES; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MUCIN-1; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; SIGNAL TRANSDUCTION; TIME FACTORS; TREFOIL FACTOR-2;

EID: 84930385772     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2014-307175     Document Type: Article

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