Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88

Journal of Immunology

Volumn 188, Issue 4, 2012, Pages 2014-2022

  Kato, Kosuke ^a   Lillehoj, Erik P ^b   Park, Yong Sung ^a   Umehara, Tsuyoshi ^a   Hoffman, Nicholas E ^a   Madesh, Muniswamy ^a   Kim, K Chul ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 1; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 5; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VIVO STUDY; LUNG ADENOCARCINOMA; LUNG HOMOGENATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; EPITHELIAL CELLS; FLAGELLIN; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INTERLEUKIN-8; LUNG; LUNG DISEASES; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; MUCIN-1; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863156123     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102405     Document Type: Article

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