The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production in Helicobacter pylori infected dendritic cells

European Journal of Immunology

Volumn 43, Issue 10, 2013, Pages 2650-2658

  Kim, Dong Jae ^a,b   Park, Jong Hwan ^a,b,c   Franchi, Luigi ^a   Backert, Steffen ^d,e   Núñez, Gabriel ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Konyang University   (South Korea)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

^e UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Helicobacter pylori; IL 1 ; Inflammasome; NLRP3; NOD2

Indexed keywords

CAGA PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CRYOPYRIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; TOLL LIKE RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; CYTOKINE PRODUCTION; DENDRITIC CELL; HELICOBACTER INFECTION; HELICOBACTER PYLORI; INNATE IMMUNITY; MOUSE; NONHUMAN; PATHOGENICITY ISLAND; PRIORITY JOURNAL;

HELICOBACTER PYLORI; IL-1Β; INFLAMMASOME; NLRP3; NOD2;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL LOAD; BACTERIAL PROTEINS; CARRIER PROTEINS; DENDRITIC CELLS; GENE EXPRESSION REGULATION; GENOMIC ISLANDS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNITY, INNATE; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NOD2 SIGNALING ADAPTOR PROTEIN; TOLL-LIKE RECEPTOR 2; VIRULENCE;

EID: 84885742487     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201243281     Document Type: Article

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