-
1
-
-
0442307969
-
IκB kinases: Key regulators of the NF-κB pathway
-
Yamamoto, Y. & Gaynor, R. IκB kinases: Key regulators of the NF-κB pathway. Trends Biochem. Sci. 29, 72-79 (2003).
-
(2003)
Trends Biochem. Sci
, vol.29
, pp. 72-79
-
-
Yamamoto, Y.1
Gaynor, R.2
-
2
-
-
4444376712
-
Signaling to NF-κB
-
Hayden, M. S. & Ghosh, S. Signaling to NF-κB. Genes Dev. 18 2195-2224 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
3
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
Li, Y., Liu, D., Chen, D., Kharbanda, S. & Kufe, D. Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22, 6107-6110 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
Kharbanda, S.4
Kufe, D.5
-
4
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents
-
Ren, J. et al. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents. Cancer Cell 5, 163-175 (2004).
-
(2004)
Cancer Cell
, vol.5
, pp. 163-175
-
-
Ren, J.1
-
5
-
-
13844262819
-
Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
-
Wei, X., Xu, H. & Kufe, D. Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 17, 167-178 (2005).
-
(2005)
Cancer Cell
, vol.17
, pp. 167-178
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
6
-
-
28544448610
-
MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin
-
Huang, L. et al. MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin. Cancer Res. 65 10413-10422 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 10413-10422
-
-
Huang, L.1
-
7
-
-
30744474431
-
MUC1 oncoprotein stabilizes and activates estrogen receptor alpha
-
Wei, X., Xu, H. & Kufe, D. MUC1 oncoprotein stabilizes and activates estrogen receptor alpha. Mol. Cell 21, 295-305 (2006).
-
(2006)
Mol. Cell
, vol.21
, pp. 295-305
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
8
-
-
0032589935
-
IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
-
Mercurio, F. et al. IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol. Cell Biol. 19, 1526-1538 (1999).
-
(1999)
Mol. Cell Biol
, vol.19
, pp. 1526-1538
-
-
Mercurio, F.1
-
9
-
-
0025129726
-
Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
-
Soule, H. D. et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 50, 6075-6086 (1990).
-
(1990)
Cancer Res
, vol.50
, pp. 6075-6086
-
-
Soule, H.D.1
-
10
-
-
0034854417
-
-
Muthuswamy, S. K., Li, D., Lelievre, S., Bissell, M. J. & Brugge, J. S. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nature Cell Biol. 3, 785-792 (2001).
-
Muthuswamy, S. K., Li, D., Lelievre, S., Bissell, M. J. & Brugge, J. S. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nature Cell Biol. 3, 785-792 (2001).
-
-
-
-
11
-
-
0029850644
-
Tumor necrosis factor-α: A multifunctional regulator of mammary gland development
-
Varela, L. M. & Ip, M. M. Tumor necrosis factor-α: A multifunctional regulator of mammary gland development. Endocrinology 137, 4915-4924 (1996).
-
(1996)
Endocrinology
, vol.137
, pp. 4915-4924
-
-
Varela, L.M.1
Ip, M.M.2
-
12
-
-
0030752475
-
The epidermal growth factor receptor is not required for tumor necrosis factor-α action in normal mammary epithelial cells
-
Varela, L. M., Darcy, K. M. & Ip, M. M. The epidermal growth factor receptor is not required for tumor necrosis factor-α action in normal mammary epithelial cells. Endocrinology 138, 3891-3900 (1997).
-
(1997)
Endocrinology
, vol.138
, pp. 3891-3900
-
-
Varela, L.M.1
Darcy, K.M.2
Ip, M.M.3
-
13
-
-
0033752746
-
Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells
-
Lee, P. P., Hwang, J. J., Murphy, G. & Ip, M. M. Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells. Endocrinology 141 3764-3773 (2000).
-
(2000)
Endocrinology
, vol.141
, pp. 3764-3773
-
-
Lee, P.P.1
Hwang, J.J.2
Murphy, G.3
Ip, M.M.4
-
14
-
-
0342844268
-
Dynamic expression and activity of NF-κB during post-natal mammary gland morphogenesis
-
Brantley, D. M. et al. Dynamic expression and activity of NF-κB during post-natal mammary gland morphogenesis. Mech. Dev. 97 149-155 (2000).
-
(2000)
Mech. Dev
, vol.97
, pp. 149-155
-
-
Brantley, D.M.1
-
15
-
-
0035007465
-
Regulation of milk protein gene expression in normal mammary epithelial cells by tumor necrosis factor
-
Shea-Eaton, W. K., Lee, P. P. & Ip, M. M. Regulation of milk protein gene expression in normal mammary epithelial cells by tumor necrosis factor. Endocrinology 142, 2558-2568 (2001).
-
(2001)
Endocrinology
, vol.142
, pp. 2558-2568
-
-
Shea-Eaton, W.K.1
Lee, P.P.2
Ip, M.M.3
-
16
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/ APO-1-initiated apoptosis
-
Ting, A. T., Pimentel-Muinos, F. X. & Seed, B. RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/ APO-1-initiated apoptosis. EMBO J. 15, 6189-6196 (1996).
-
(1996)
EMBO J
, vol.15
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
17
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-κB signal
-
Kelliher, M. A. et al. The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8, 297-303 (1998).
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
-
18
-
-
0035021123
-
The alpha and beta subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
-
Devin, A. et al. The alpha and beta subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol. Cell Biol. 21, 3986-3994 (2001).
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 3986-3994
-
-
Devin, A.1
-
19
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
Hsu, H., Shu, H.-B., Pan, M.-G. & Goeddel, D. V. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 184, 299-308 (1996).
-
(1996)
Cell
, vol.184
, pp. 299-308
-
-
Hsu, H.1
Shu, H.-B.2
Pan, M.-G.3
Goeddel, D.V.4
-
20
-
-
0033537719
-
Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation
-
Delhase, M., Hayakawa, M., Chen, Y. & Karin, M. Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation. Science 284, 309-313 (1999).
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
Karin, M.4
-
21
-
-
0021740104
-
Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
-
Kufe, D. et al. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 3, 223-232 (1984).
-
(1984)
Hybridoma
, vol.3
, pp. 223-232
-
-
Kufe, D.1
-
22
-
-
0842288993
-
Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells
-
Li, Q., Ren, J. & Kufe, D. Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells. Biochem. Biophys. Res. Commun. 315, 471-476 (2004).
-
(2004)
Biochem. Biophys. Res. Commun
, vol.315
, pp. 471-476
-
-
Li, Q.1
Ren, J.2
Kufe, D.3
-
23
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang, C. et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351 (2001).
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
-
24
-
-
0037422858
-
TAK1 is critical for IκB kinase-mediated activation of the NF-κB pathway
-
Takaesu, G. et al. TAK1 is critical for IκB kinase-mediated activation of the NF-κB pathway. J. Mol. Biol. 326, 105-115 (2003).
-
(2003)
J. Mol. Biol
, vol.326
, pp. 105-115
-
-
Takaesu, G.1
-
25
-
-
0033605575
-
Mitogen-activated protein kinase/ERK kinase kinases-2 and 3 activate nuclear factor-kB through IκB kinase-α and IκB kinase-β
-
Zhao, Q. & Lee, F. S. Mitogen-activated protein kinase/ERK kinase kinases-2 and 3 activate nuclear factor-kB through IκB kinase-α and IκB kinase-β. J. Biol.Chem. 274, 8355-8358 (1999).
-
(1999)
J. Biol.Chem
, vol.274
, pp. 8355-8358
-
-
Zhao, Q.1
Lee, F.S.2
-
26
-
-
0346243941
-
Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
-
Ishitani, T. et al. Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling. EMBO J. 22, 6277-6288 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 6277-6288
-
-
Ishitani, T.1
-
27
-
-
4344712350
-
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
-
Kanayama, A. et al. TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains. Mol. Cell 15, 535-548 (2004).
-
(2004)
Mol. Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
-
28
-
-
0036895537
-
Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis
-
Komatsu, Y. et al. Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis. Mech. Dev. 119, 239-249 (2002).
-
(2002)
Mech. Dev
, vol.119
, pp. 239-249
-
-
Komatsu, Y.1
-
29
-
-
30044449755
-
TAK1 is recruited to the tumor necrosis factor-alpha (TNF-α) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-κB activation
-
Blonska, M. et al. TAK1 is recruited to the tumor necrosis factor-alpha (TNF-α) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-κB activation. J. Biol. Chem. 280, 43056-43063 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 43056-43063
-
-
Blonska, M.1
-
30
-
-
33745298519
-
Nuclear factor-κB in cancer development and progression
-
Karin, M. Nuclear factor-κB in cancer development and progression. Nature 441, 431-436 (2006).
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
31
-
-
33644835965
-
Heat shock proteins in cancer: Chaperones of tumorigenesis
-
Calderwood, S. K., Khaleque, M. A., Sawyer, D. B. & Ciocca, D. R. Heat shock proteins in cancer: Chaperones of tumorigenesis. Trends Biochem. Sci. 31, 164-172 (2006).
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 164-172
-
-
Calderwood, S.K.1
Khaleque, M.A.2
Sawyer, D.B.3
Ciocca, D.R.4
-
32
-
-
0034655650
-
MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets
-
Dyomin, V. G. et al. MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets. Blood 95, 2666-2671 (2000).
-
(2000)
Blood
, vol.95
, pp. 2666-2671
-
-
Dyomin, V.G.1
-
33
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
Baldwin, A. S. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J. Clin. Invest. 107, 241-246 (2001).
-
(2001)
J. Clin. Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
34
-
-
0030927167
-
Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth
-
Nakshatri, H., Bhat-Nakshatri, P., Martin, D. A., Goulet, R. J., Jr. & Sledge, G. W., Jr Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth. Mol. Cell Biol. 17, 3629-3639 (1997).
-
(1997)
Mol. Cell Biol
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
Goulet Jr., R.J.4
Sledge Jr, G.W.5
-
35
-
-
30344437854
-
Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness
-
Sotgia, F. et al. Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. Am. J. Pathol. 168 292-309 (2006).
-
(2006)
Am. J. Pathol
, vol.168
, pp. 292-309
-
-
Sotgia, F.1
|