Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Boergeling, Yvonne ^a   Rozhdestvensky, Timofey S ^a   Schmolke, Mirco ^a,e   Resa Infante, Patricia ^b   Robeck, Thomas ^a   Randau, Gerrit ^a   Wolff, Thorsten ^c   Gabriel, Gülsah ^b   Brosius, Jürgen ^a,d   Ludwig, Stephan ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c ROBERT KOCH INSTITUTE   (Germany)

^d BRANDENBURG MEDICAL SCHOOL THEODOR FONTANE   (Germany)

^e UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; PLASMID DNA; PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; RNA BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN; MESSENGER RNA; PB2 PROTEIN, INFLUENZAVIRUS A; RNA DIRECTED RNA POLYMERASE; VIRAL PROTEIN; VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHLOROCEBUS; CONTROLLED STUDY; DOG; FRAMESHIFT MUTATION; HEMAGGLUTINATION TEST; HUMAN; HUMAN CELL; INFLUENZA VIRUS; INFLUENZA VIRUS A H5N1; INNATE IMMUNITY; LUCIFERASE ASSAY; MASS SPECTROMETRY; MOUSE; NONHUMAN; NORTHERN BLOTTING; OPEN READING FRAME; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SATELLITE VIRUS; VESICULOVIRUS; WEIGHT REDUCTION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; GENETICS; IMMUNOPRECIPITATION; INFLUENZA A VIRUS; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; METABOLISM; ORTHOMYXOVIRUS INFECTION; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; VIROLOGY; VIRUS REPLICATION;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE; VESICULAR STOMATITIS VIRUS;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; HEMAGGLUTINATION TESTS; IMMUNOPRECIPITATION; INFLUENZA A VIRUS; INTERFERON TYPE I; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA REPLICASE; RNA, MESSENGER; RNA, VIRAL; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR CELLS, CULTURED; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84930321672     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004924     Document Type: Article

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