Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice

Toxicology and Applied Pharmacology

Volumn 286, Issue 2, 2015, Pages 102-111

  Harris, Todd R ^a   Bettaieb, Ahmed ^a   Kodani, Sean ^a   Dong, Hua ^a   Myers, Richard ^a   Chiamvimonvat, Nipavan ^a   Haj, Fawaz G ^a   Hammock, Bruce D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Carbon tetrachloride; Endoplasmic reticulum stress; Fibrosis; Soluble epoxide hydrolase

Indexed keywords

CARBON TETRACHLORIDE; COLLAGEN; COLLAGEN 1A2; COLLAGEN 3A1; DRINKING WATER; ENZYME INHIBITOR; EPOXIDE HYDROLASE; MESSENGER RNA; SOLUBLE EPOXIDE HYDROLASE; UNCLASSIFIED DRUG; 1-TRIFLUOROMETHOXYPHENYL-3-(1-PROPIONYLPIPERIDINE-4-YL)UREA; CARBANILAMIDE DERIVATIVE; HYDROXYPROLINE; OXYLIPIN; PIPERIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; GENE EXPRESSION; INFLAMMATION; LIVER FIBROSIS; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; LIVER; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY;

ANIMALIA; MUS;

ANIMALS; CARBON TETRACHLORIDE; COLLAGEN; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; EPOXIDE HYDROLASES; HYDROXYPROLINE; LIVER; LIVER CIRRHOSIS; MICE; MICE, INBRED C57BL; OXYLIPINS; PHENYLUREA COMPOUNDS; PIPERIDINES;

EID: 84930274047     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.03.022     Document Type: Article

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