Hepatoprotective properties of sesamin against CCl4 induced oxidative stress-mediated apoptosis in mice via JNK pathway

Food and Chemical Toxicology

Volumn 64, Issue , 2014, Pages 41-48

  Ma, Jie Qiong ^a   Ding, Jie ^a   Zhang, Li ^a   Liu, Chan Min ^b  

^a SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING   (China)

^b JIANGSU NORMAL UNIVERSITY   (China)

Author keywords

Apoptosis; JNK; Liver; Oxidative stress; Sesamin

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CASPASE 3; CYTOCHROME C; PLACEBO; PROTEIN BAK; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SESAMIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG TARGETING; ENZYME ACTIVITY; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER DYSFUNCTION; LIVER INJURY; LIVER LEVEL; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; UPREGULATION;

MUS; SESAMUM INDICUM;

ALANINE AMINOTRANSFERASE; ALT; APOPTOSIS; ASPARTATE AMINOTRANSFERASE; AST; CARBON TETRACHLORIDE; CCL(4); DEOXYRIBONUCLEOTIDYL TRANSFERASE (TDT)-MEDIATED DUTP-FLUORESCEIN ISOTHIOCYANATE (FITC) NICK-END LABELING.; JNK; LIVER; NECROSIS FACTOR-ALPHA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; ROS; SES; SESAMIN; TAC; TBARS; THE C-JUN N-TERMINAL KINASES; THE TOTAL ANTIOXIDANT CAPACITY; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TNF-Α; TUNEL;

ANIMALS; APOPTOSIS; CARBON TETRACHLORIDE; CASPASE 3; DIOXOLES; DRUG-INDUCED LIVER INJURY; ENZYME ACTIVATION; LIGNANS; LIVER; MALE; MAP KINASE KINASE 4; MICE; MICE, INBRED ICR; OXIDATIVE STRESS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES;

EID: 84890245314     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.11.017     Document Type: Article

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