Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 46, 2012, Pages

  Castillo, Eliseo F ^a   Dekonenko, Alexander ^a   Arko Mensah, John ^a   Mandell, Michael A ^a   Dupont, Nicolas ^a   Jiang, Shanya ^a   Delgado Vargas, Monica ^a   Timmins, Graham S ^b   Bhattacharya, Dhruva ^a   Yang, Hongliang ^c   Hutt, Julie ^d   Lyons, C Rick ^a   Dobos, Karen M ^c   Deretic, Vojo ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c Department of Ecosystem Science and Sustainability   (United States)

^d LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Calpain; Inflammasome; Macrophage; Th17 response

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 1ALPHA;

ANIMAL CELL; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOPHAGY; BACTERIAL GROWTH; BACTERIAL LOAD; CYTOKINE RELEASE; LUNG TUBERCULOSIS; MACROPHAGE; MOUSE; MOUSE STRAIN; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; AUTOPHAGY; INTERLEUKIN-17; INTERLEUKIN-1ALPHA; MACROPHAGES; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL INFILTRATION; NEUTROPHILS; T-LYMPHOCYTES; TUBERCULOSIS;

BACTERIA (MICROORGANISMS); MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84869217908     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210500109     Document Type: Article

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