An acetyl-methyl switch drives a conformational change in p53

Structure

Volumn 23, Issue 2, 2015, Pages 322-331

  Tong, Qiong ^a   Mazur, Sharlyn J ^b   Rincon Arano, Hector ^c   Rothbart, Scott B ^d   Kuznetsov, Dmitry M ^e   Cui, Gaofeng ^f   Liu, Wallace H ^a   Gete, Yantenew ^b   Klein, Brianna J ^a   Jenkins, Lisa ^b   Mer, Georges ^f   Kutateladze, Andrei G ^e   Strahl, Brian D ^d   Groudine, Mark ^c,g   Appella, Ettore ^b   Kutateladze, Tatiana G ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c USA   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF DENVER   (United States)

^f MAYO GRADUATE SCHOOL   (United States)

^g UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

53BP1 PROTEIN; BINDING PROTEIN; DNA; E1A ASSOCIATED P300 PROTEIN; PROTEIN P53; SERINE; THREONINE; UNCLASSIFIED DRUG; LIGAND; LYSINE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BIOCHEMISTRY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA DAMAGE; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE; PEPTIDOMICS; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; TANDEM TUDOR DOMAIN; CHEMICAL STRUCTURE; CHEMISTRY; DNA METHYLATION; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DNA DAMAGE; DNA METHYLATION; HUMANS; LIGANDS; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84930189594     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2014.12.010     Document Type: Article

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