The MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression

Journal of Biological Chemistry

Volumn 285, Issue 48, 2010, Pages 37725-37732

  West, Lisandra E ^a   Roy, Siddhartha ^b   Lachmi Weiner, Karin ^a   Hayashi, Ryo ^c   Shi, Xiaobing ^d   Appella, Ettore ^c   Kutateladze, Tatiana G ^b   Gozani, Or ^a,e  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e 371 Serra Mall ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN TUMORS; CHROMATIN COMPACTION; CRYSTALLOGRAPHIC STUDIES; DNA DAMAGES; IN-CELL; METHYLTRANSFERASES; MOLECULAR MECHANISM; MONOMETHYLATION; POST-TRANSLATIONAL MODIFICATIONS; TARGET GENES; TRANSACTIVATION; TRANSCRIPT LEVEL; TUMOR SUPPRESSOR PROTEINS;

ALKYLATION; GENES; METHYLATION; PROTEINS; TUMORS;

AMINO ACIDS;

LYSINE; PROTEIN P21; PROTEIN P53; PROTEIN SET8; PUMA PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BRAIN CANCER; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; GENE REPRESSION; GENE TARGETING; GENETIC ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; APOPTOSIS REGULATORY PROTEINS; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LYSINE; METHYLATION; NEOPLASM PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78549291445     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.139527     Document Type: Article

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