Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease

Structure

Volumn 22, Issue 9, 2014, Pages 1333-1340

  Lin, S Jack ^a   Dong, Ken C ^a   Eigenbrot, Charles ^a   Van Lookeren Campagne, Menno ^a   Kirchhofer, Daniel ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ELASTASE; NEUTROPHIL SERINE PROTEINASE 4; SERINE PROTEINASE; TRYPSIN FOLD PROTEASE; UNCLASSIFIED DRUG; NSP4 SERINE PROTEASE; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROGEN BOND; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; STATIC ELECTRICITY; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; KINETICS; X RAY CRYSTALLOGRAPHY;

MAMMALIA;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY;

EID: 84930065206     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2014.07.008     Document Type: Article

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