SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G

Blood

Volumn 121, Issue 19, 2013, Pages 3900-3907

  Baumann, Mathias ^a,b   Pham, Christine T N ^c   Benarafa, Charaf ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CATHEPSIN G; LEUCYLLEUCINE METHYL ESTER; LEUKOCYTE ELASTASE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SERINE PROTEINASE INHIBITOR; SERPIN B1; UNCLASSIFIED DRUG; SERPINB1A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; BONE MARROW; BONE MARROW TRANSPLANTATION; BYSTANDER EFFECT; CELL DEATH; CELL PERMEABILIZATION; CELL SURVIVAL; CHIMERA; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME INHIBITION; ERYTHROCYTE COUNT; FEMALE; GENE DELETION; GRANULOPOIESIS; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE COUNT; MALE; MOUSE; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; THROMBOCYTE COUNT; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CELL CULTURE; DOWN REGULATION; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; CATHEPSIN G; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; ORGAN SPECIFICITY; SERPINS;

MLCS; MLOWN;

EID: 84880449571     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-09-455022     Document Type: Article

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