SERPINB1 upregulation is associated with in vivo complex formation with neutrophil elastase and cathepsin G in a baboon model of bronchopulmonary dysplasia

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 291, Issue 4, 2006, Pages

  Yasumatsu, Ryuji ^a   Altiok, Ozden ^a   Benarafa, Charaf ^b   Yasumatsu, Chie ^a   Bingol Karakoc, Gulbin ^a   Remold O'Donnell, Eileen ^b   Cataltepe, Sule ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b CENTER FOR BLOOD RESEARCH   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Monocyte neutrophil elastase inhibitor; Premature; Protease; Serpin

Indexed keywords

CATHEPSIN G; LEUKOCYTE ELASTASE; SERINE PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BABOON; COMPLEX FORMATION; CONTROLLED STUDY; EPITHELIUM CELL; GESTATIONAL AGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOLOCALIZATION; IMMUNOPRECIPITATION; ION TRAP MASS SPECTROMETRY; LUNG DEVELOPMENT; LUNG DYSPLASIA; LUNG FLUID; LUNG LAVAGE; MACROPHAGE; MAST CELL; MORBIDITY; NEUTROPHIL; NONHUMAN; ONTOGENY; PNEUMONIA; PREMATURITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOPULMONARY DYSPLASIA; CATHEPSINS; DISEASE MODELS, ANIMAL; EMBRYO; EMBRYONIC DEVELOPMENT; GESTATIONAL AGE; HUMANS; IMMUNOLOGIC TECHNIQUES; INFANT, NEWBORN; LEUKOCYTE ELASTASE; LUNG; PAPIO; RNA, MESSENGER; SERINE ENDOPEPTIDASES; SERPINS; UP-REGULATION;

EID: 33749365853     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00507.2005     Document Type: Article

References (54)

1. Altiok O, Yasumatsu R, Bingol-Karakoc G, Riese RJ, Stahlman MT, Dwyer W, Pierce RA, Bromme D, Weber E, and Cataltepe S. Imbalance between cysteine proteases and inhibitors in a baboon model of bronchopulmonary dysplasia. Am J Respir Crit Care Med 173: 318-326, 2006.
2. Askew YS, Pak SC, Luke CJ, Askew DJ, Cataltepe S, Mills DR, Kato H, Lehoczky J, Dewar K, Birren B, and Silverman GA. SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases. J Biol Chem 276: 49320-49330, 2001.
3. Bancalari E, Claure N, and Sosenko IR. Bronchopulmonary dysplasia: changes in pathogenesis, epidemiology and definition. Semin Neonatol 8: 63-71, 2003.
4. Benarafa C and Remold-O'Donnell E. The ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebrates. Proc Natl Acad Sci USA 102: 11367-11372, 2005.
5. Bland RD. Neonatal chronic lung disease in the post-surfactant era. Biol Neonate 88: 181-191, 2005.
6. Bland RD, Albertine KH, Pierce RA, Starcher BC, and Carlton DP. Impaired alveolar development and abnormal lung elastin in preterm lambs with chronic lung injury: potential benefits of retinol treatment. Biol Neonate 84: 101-102, 2003.
7. Cataltepe S, Gornstein ER, Schick C, Kamachi Y, Chatson K, Fries J, Silverman GA, and Upton MP. Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas. J Histochem Cytochem 48: 113-122, 2000.
8. Coalson JJ. Experimental models of bronchopulmonary dysplasia. Biol Neonate 71, Suppl 1: 35-38, 1997.
9. Coalson JJ. Pathology of new bronchopulmonary dysplasia. Semin Neonatol 8: 73-81, 2003.
10. Coalson JJ, Winter VT, Gerstmann DR, Idell S, King RJ, and Delemos RA. Pathophysiologic, morphometric, and biochemical studies of the premature baboon with bronchopulmonary dysplasia. Am Rev Respir Dis 145: 872-881, 1992.
11. Coalson JJ, Winter VT, Siler-Khodr T, and Yoder BA. Neonatal chronic lung disease in extremely immature baboons. Am J Respir Crit Care Med 160: 1333-1346, 1999.
12. Cooley J, Mathieu B, Remold-O'Donnell E, and Mandle RJ. Production of recombinant human monocyte/neutrophil elastase inhibitor (rM/NEI). Protein Expr Purif 14: 38-44, 1998.
13. Cooley JRF, Sontag MK, Osberg I, Accurso FJ, and Remold-O'Donnell E. MNEI (monocyte/neutrophil elastase inhibitor) is found at increased levels in cystic fibrosis lavage fluid (Abstract). Pediatr Pulmonol 31, Suppl 22: 271, 2001.
14. Cooley J, Takayama TK, Shapiro SD, Schechter NM, and Remold-O'Donnell E. The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites. Biochemistry 40: 15762-15770, 2001.
15. Fujimura M, Kitajima H, and Nakayama M. Increased leukocyte elastase of the tracheal aspirate at birth and neonatal pulmonary emphysema. Pediatrics 92: 564-569, 1993.
16. Groneck P, Gotze-Speer B, Oppermann M, Eiffert H, and Speer CP. Association of pulmonary inflammation and increased microvascular permeability during the development of bronchopulmonary dysplasia: a sequential analysis of inflammatory mediators in respiratory fluids of high-risk preterm neonates. Pediatrics 93: 712-718, 1994.
17. Gross SJ, Iannuzzi DM, Kveselis DA, and Anbar RD. Effect of preterm birth on pulmonary function at school age: a prospective controlled study. J Pediatr 133: 188-192, 1998.
18. Halvorsen T, Skadberg BT, Eide GE, Roksund OD, Carlsen KH, and Bakke P. Pulmonary outcome in adolescents of extreme preterm birth: a regional cohort study. Acta Paediatr 93: 1294-1300, 2004.
19. Hirche TO, Crouch EC, Espinola M, Brokelman TJ, Mecham RP, DeSilva N, Cooley J, Remold-O'Donnell E, and Belaaouaj A. Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain. J Biol Chem 279: 27688-27698, 2004.
20. Jobe AH. Antenatal factors and the development of bronchopulmonary dysplasia. Semin Neonatol 8: 9-17, 2003.
21. Jobe AH. Pulmonary surfactant therapy. N Engl J Med 328: 861-868, 1993.
22. Lemons JA, Bauer CR, Oh W, Korones SB, Papile LA, Stoll BJ, Verter J, Temprosa M, Wright LL, Ehrenkranz RA, Fanaroff AA, Stark A, Carlo W, Tyson JE, Donovan EF, Shankaran S, and Stevenson DK. Very low birth weight outcomes of the National Institute of Child Health And Human Development Neonatal Research Network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics 107: E1, 2001.
23. Lyle RE, Tryka AF, Griffin WS, and Taylor BJ. Tryptase immunoreactive mast cell hyperplasia in bronchopulmonary dysplasia. Pediatr Pulmonol 19: 336-343, 1995.
24. Maniscalco WM, Watkins RH, Pryhuber GS, Bhatt A, Shea C, and Huyck H. Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons. Am J Physiol Lung Cell Mol Physiol 282: L811-L823, 2002.
25. Maniscalco WM, Watkins RH, Roper JM, Staversky R, and O'Reilly MA. Hyperoxic ventilated premature baboons have increased p53, oxidant DNA damage and decreased VEGF expression. Pediatr Res 58: 549-556, 2005.
26. McCurnin DC, Pierce RA, Chang LY, Gibson LL, Osborne-Lawrence S, Yoder BA, Kerecman JD, Albertine KH, Winter VT, Coalson JJ, Crapo JD, Grubb PH, and Shaul PW. Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease. Am J Physiol Lung Cell Mol Physiol 288: L450-L459, 2005.
27. McElvaney NG, Hubbard RC, Birrer P, Chernick MS, Caplan DB, Frank MM, and Crystal RG. Aerosol alpha 1-antitrypsin treatment for cystic fibrosis. Lancet 337: 392-394, 1991.
28. Merritt TA, Cochrane CG, Holcomb K, Bohl B, Hallman M, Strayer D, Edwards DD, and Gluck L. Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasia. J Clin Invest 72: 656-666, 1983.
29. Northway WJ, Rosan RC, and Porter DY. Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia. N Engl J Med 276: 357-368, 1967.
30. Ogden BE, Murphy SA, Saunders GC, Pathak D, and Johnson JD. Neonatal lung neutrophils and elastase/proteinase inhibitor imbalance. Am Rev Respir Dis 130: 817-821, 1984.
31. Rees DD, Rogers RA, Cooley J, Mandle RJ, Kenney DM, and Remold-O'Donnell E. Recombinant human monocyte/neutrophil elastase inhibitor protects rat lungs against injury from cystic fibrosis airway secretions. Am J Respir Cell Mol Biol 20: 69-78, 1999.
32. Remold-O'Donnell E. A fast-acting elastase inhibitor in human monocytes. J Exp Med 162: 2142-2155, 1985.
33. Remold-O'Donnell E. The ovalbumin family of serpin proteins. FEBS Lett 315: 105-108, 1993.
34. Remold-O'Donnell E, Nixon JC, and Rose RM. Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils. J Exp Med 169: 1071-1086, 1989.
35. Rubio F, Cooley J, Accurso FJ, and Remold-O'Donnell E. Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease. Thorax 59: 318-323, 2004.
36. Saugstad OD. Bronchopulmonary dysplasia-oxidative stress and antioxidants. Semin Neonatol 8: 39-49, 2003.
37. Schick C, Kamachi Y, Bartuski AJ, Cataltepe S, Schechter NM, Pemberton PA, and Silverman GA. Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase. J Biol Chem 272: 1849-1855, 1997.
38. Schick C, Pemberton PA, Shi GP, Kamachi Y, Cataltepe S, Bartuski AJ, Gornstein ER, Bromme D, Chapman HA, and Silverman GA. Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis. Biochemistry 37: 5258-5266, 1998.
39. Schmidt B, Asztalos EV, Roberts RS, Robertson CM, Sauve RS, and Whitfield MF. Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms. JAMA 289: 1124-1129, 2003.
40. Short EJ, Klein NK, Lewis BA, Fulton S, Eisengart S, Kercsmar C, Baley J, and Singer LT. Cognitive and academic consequences of bronchopulmonary dysplasia and very low birth weight: 8-year-old outcomes. Pediatrics 112: e359, 2003.
41. Silverman GA, Whisstock JC, Askew DJ, Pak SC, Luke CJ, Cataltepe S, Irving JA, and Bird PI. Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci 61: 301-325, 2004.
42. Sluis KB, Darlow BA, Vissers MC, and Winterbourn CC. Proteinase- antiproteinase balance in tracheal aspirates from neonates. Eur Respir J 7: 251-259, 1994.
43. Smith VC, Zupancic JA, McCormick MC, Croen LA, Greene J, Escobar GJ, and Richardson DK. Trends in severe bronchopulmonary dysplasia rates between 1994 and 2002. J Pediatr 146: 469-473, 2005.
44. Speer CP. Inflammation and bronchopulmonary dysplasia. Semin Neonatol 8: 29-38, 2003.
45. Speer CP. New insights into the pathogenesis of pulmonary inflammation in preterm infants. Biol Neonate 79: 205-209, 2001.
46. 1-Proteinase inhibitor therapy for the prevention of bronchopulmonary dysplasia in premature infants (Abstract). Pediatr Res 39: 247A, 1996.
47. Stiskal JA, Ito S, Cox DW, Shennan AT, O'Brien KK, Kelly EN, Longley TB, Rabinovitch M, and Dunn MS. Functional and antigenic concentrations of alpha-1-proteinase inhibitor after administration for the prevention of chronic lung disease of prematurity. Biol Neonate 76: 134-143, 1999.
48. Sunday ME, Yoder BA, Cuttitta F, Haley KJ, and Emanuel RL. Bombesin-like peptide mediates lung injury in a baboon model of bronchopulmonary dysplasia. J Clin Invest 102: 584-594, 1998.
49. Sveger T, Ohlsson K, Polberger S, Noack G, Morse H, and Laurin S. Tracheobronchial aspirate fluid neutrophil lipocalin, elastase- and neutrophil protease-4-α1-antitrypsin complexes, protease inhibitors and free proteolytic activity in respiratory distress syndrome. Acta Paediatr 91: 934-937, 2002.
50. Walti H, Tordet C, Gerbaut L, Saugier P, Moriette G, and Relier JP. Persistent elastase/proteinase inhibitor imbalance during prolonged ventilation of infants with bronchopulmonary dysplasia: evidence for the role of nosocomial infections. Pediatr Res 26: 351-355, 1989.
51. Watterberg KL, Carmichael DF, Gerdes JS, Werner S, Backstrom C, and Murphy S. Secretory leukocyte protease inhibitor and lung inflammation in developing bronchopulmonary dysplasia. J Pediatr 125: 264-269, 1994.
52. Yasumatsu R, Nakashima T, Azuma K, Hirakawa N, Kuratomi Y, Tomita K, Cataltepe S, Silverman GA, Clayman GL, and Komiyama S. SCCA1 expression in T-lymphocytes peripheral to cancer cells is associated with the elevation of serum SCC antigen in squamous cell carcinoma of the tongue. Cancer Lett 167: 205-213, 2001.
53. Yasutake A and Powers JC. Reactivity of human leukocyte elastase and porcine pancreatic elastase toward peptide 4-nitroanilides containing model desmosine residues. Evidence that human leukocyte elastase is selective for cross-linked regions of elastin. Biochemistry 20: 3675-3679, 1981.
54. Zeng W and Remold-O'Donnell E. Human monocyte/neutrophil elastase inhibitor (MNEI) is regulated by PU.1/Spi-1, Sp1, and NF-κB. J Cell Biochem 78: 519-532, 2000.