Pedunculopontine cell loss and protein aggregation direct microglia activation in parkinsonian rats

Brain Structure and Function

Volumn 221, Issue 4, 2016, Pages 2319-2341

  Elson, Joanna L ^a,b   Yates, Abi ^c   Pienaar, Ilse S ^d,e  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NORTH WEST UNIVERSITY   (South Africa)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e NORTHUMBRIA UNIVERSITY   (United Kingdom)

Author keywords

Lactacystin; Microglia; Neuronophagia; Parkinson s disease; Pedunculopontine tegmental nucleus; Synuclein

Indexed keywords

ACETYLCHOLINE; ALPHA SYNUCLEIN; CHOLINE ACETYLTRANSFERASE; LACTACYSTIN; ACETYLCYSTEINE; TYROSINE 3 MONOOXYGENASE;

ADULT; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL LOSS; CHOLINERGIC NERVE CELL; CIRCLING BEHAVIOR; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; MALE; MICROGLIA; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; RAT; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; METABOLISM; NERVE CELL; PARKINSONISM; PATHOLOGY; PROTEINOSIS; SPRAGUE DAWLEY RAT; SUBSTANTIA NIGRA PARS COMPACTA;

ACETYLCYSTEINE; ALPHA-SYNUCLEIN; ANIMALS; CELL COUNT; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC NEURONS; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; MALE; MICROGLIA; NEURONS; PARKINSON DISEASE; PARKINSONIAN DISORDERS; PARS COMPACTA; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PROTEIN AGGREGATION, PATHOLOGICAL; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE 3-MONOOXYGENASE;

EID: 84929688751     PISSN: 18632653     EISSN: 18632661     Source Type: Journal    
DOI: 10.1007/s00429-015-1045-4     Document Type: Article

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