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Volumn 210, Issue 2, 2012, Pages 187-194

A novel use of combined tyrosine hydroxylase and silver nucleolar staining to determine the effects of a unilateral intrastriatal 6-hydroxydopamine lesion in the substantia nigra: A stereological study

Author keywords

6 Hydroxydopamine; 6 OHDA; AgNOR; HPLC EC; Neuronal number; Neuronal volume; NOR; Silver nucleolar stain; SNpc; Stereology; Substantia nigra pars compacta; TH; TH AgNOR

Indexed keywords

DEXAMPHETAMINE; DOPAMINE; OXIDOPAMINE;

EID: 84865438509     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2012.07.013     Document Type: Article
Times cited : (22)

References (37)
  • 1
    • 44349106406 scopus 로고    scopus 로고
    • Reduced numbers of dopamine neurons in the substantia nigra pars compacta and ventral tegmental area of rats fed an n-3 polyunsaturated fatty acid-deficient diet: a stereological study
    • Ahmad S., Park J., Radel J., Levant B. Reduced numbers of dopamine neurons in the substantia nigra pars compacta and ventral tegmental area of rats fed an n-3 polyunsaturated fatty acid-deficient diet: a stereological study. Neurosci Lett 2008, 438:303-307.
    • (2008) Neurosci Lett , vol.438 , pp. 303-307
    • Ahmad, S.1    Park, J.2    Radel, J.3    Levant, B.4
  • 2
    • 79960673874 scopus 로고    scopus 로고
    • Young and middle-aged rats exhibit isometric forelimb force control deficits in a model of early-stage Parkinson's disease
    • Bethel-Brown C.S., Morris J.K., Stanford J.A. Young and middle-aged rats exhibit isometric forelimb force control deficits in a model of early-stage Parkinson's disease. Behav Brain Res 2011, 225:97-103.
    • (2011) Behav Brain Res , vol.225 , pp. 97-103
    • Bethel-Brown, C.S.1    Morris, J.K.2    Stanford, J.A.3
  • 3
    • 77956060631 scopus 로고    scopus 로고
    • Within-session analysis of amphetamine-elicited rotation behavior reveals differences between young adult and middle-aged F344/BN rats with partial unilateral striatal dopamine depletion
    • Bethel-Brown C.S., Zhang H., Fowler S.C., Chertoff M.E., Watson G.S., Stanford J.A. Within-session analysis of amphetamine-elicited rotation behavior reveals differences between young adult and middle-aged F344/BN rats with partial unilateral striatal dopamine depletion. Pharmacol Biochem Behav 2010, 96:423-428.
    • (2010) Pharmacol Biochem Behav , vol.96 , pp. 423-428
    • Bethel-Brown, C.S.1    Zhang, H.2    Fowler, S.C.3    Chertoff, M.E.4    Watson, G.S.5    Stanford, J.A.6
  • 4
    • 0021089452 scopus 로고
    • Aetiology of Parkinson's disease
    • Calne D., Langston J. Aetiology of Parkinson's disease. Lancet 1983, 2:1457-1459.
    • (1983) Lancet , vol.2 , pp. 1457-1459
    • Calne, D.1    Langston, J.2
  • 5
    • 0034800339 scopus 로고    scopus 로고
    • Subthalamic nucleus lesions are neuroprotective against terminal 6-OHDA-induced striatal lesions and restore postural balancing reactions
    • Carvalho G.A., Nikkhah G. Subthalamic nucleus lesions are neuroprotective against terminal 6-OHDA-induced striatal lesions and restore postural balancing reactions. Exp Neurol 2001, 171:405-417.
    • (2001) Exp Neurol , vol.171 , pp. 405-417
    • Carvalho, G.A.1    Nikkhah, G.2
  • 6
    • 77955185130 scopus 로고    scopus 로고
    • Dopamine receptor alterations in female rats with diet-induced decreased brain docosahexaenoic acid (DHA): interactions with reproductive status
    • Davis P.F., Ozias M.K., Carlson S.E., Reed G.A., Winter M.K., McCarson K.E., et al. Dopamine receptor alterations in female rats with diet-induced decreased brain docosahexaenoic acid (DHA): interactions with reproductive status. Nutr Neurosci 2010, 13:161-169.
    • (2010) Nutr Neurosci , vol.13 , pp. 161-169
    • Davis, P.F.1    Ozias, M.K.2    Carlson, S.E.3    Reed, G.A.4    Winter, M.K.5    McCarson, K.E.6
  • 7
    • 18144396885 scopus 로고    scopus 로고
    • Effect of intrastriatal 6-OHDA lesion on dopaminergic innervation of the rat cortex and globus pallidus
    • Debeir T., Ginestet L., François C., Laurens S., Martel J.C., Chopin P., et al. Effect of intrastriatal 6-OHDA lesion on dopaminergic innervation of the rat cortex and globus pallidus. Exp Neurol 2005, 193:444-454.
    • (2005) Exp Neurol , vol.193 , pp. 444-454
    • Debeir, T.1    Ginestet, L.2    François, C.3    Laurens, S.4    Martel, J.C.5    Chopin, P.6
  • 8
    • 3142557928 scopus 로고    scopus 로고
    • The prognostic value of the AgNOR parameter in human breast cancer depends on the pRb and p53 status
    • Derenzini M., Ceccarelli C., Santini D., Taffurelli M., Treré D. The prognostic value of the AgNOR parameter in human breast cancer depends on the pRb and p53 status. J Clin Pathol 2004, 57:755-761.
    • (2004) J Clin Pathol , vol.57 , pp. 755-761
    • Derenzini, M.1    Ceccarelli, C.2    Santini, D.3    Taffurelli, M.4    Treré, D.5
  • 9
    • 0034114866 scopus 로고    scopus 로고
    • Nucleolar size indicates the rapidity of cell proliferation in cancer tissues
    • Derenzini M., Trerè D., Pession A., Govoni M., Sirri V., Chieco P. Nucleolar size indicates the rapidity of cell proliferation in cancer tissues. J Pathol 2000, 191:181-186.
    • (2000) J Pathol , vol.191 , pp. 181-186
    • Derenzini, M.1    Trerè, D.2    Pession, A.3    Govoni, M.4    Sirri, V.5    Chieco, P.6
  • 10
    • 0036283426 scopus 로고    scopus 로고
    • Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway
    • Deumens R., Blokland A., Prickaerts J. Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol 2002, 175:303-317.
    • (2002) Exp Neurol , vol.175 , pp. 303-317
    • Deumens, R.1    Blokland, A.2    Prickaerts, J.3
  • 11
    • 77952311733 scopus 로고    scopus 로고
    • Age and Parkinson's disease-related neuronal death in the substantia nigra pars compacta
    • Eriksen N., Stark A.K., Pakkenberg B. Age and Parkinson's disease-related neuronal death in the substantia nigra pars compacta. J Neural Transm Suppl 2009, 203-213.
    • (2009) J Neural Transm Suppl , pp. 203-213
    • Eriksen, N.1    Stark, A.K.2    Pakkenberg, B.3
  • 13
    • 16244399789 scopus 로고    scopus 로고
    • Dopamine cell morphology and glial cell hypertrophy and process branching in the nigrostriatal system after striatal 6-OHDA analyzed by specific sterological tools
    • Gomide V., Bibancos T., Chadi G. Dopamine cell morphology and glial cell hypertrophy and process branching in the nigrostriatal system after striatal 6-OHDA analyzed by specific sterological tools. Int J Neurosci 2005, 115:557-582.
    • (2005) Int J Neurosci , vol.115 , pp. 557-582
    • Gomide, V.1    Bibancos, T.2    Chadi, G.3
  • 14
    • 0023760665 scopus 로고
    • The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
    • Gundersen H.J., Bagger P., Bendtsen T.F., Evans S.M., Korbo L., Marcussen N., et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988, 96:857-881.
    • (1988) APMIS , vol.96 , pp. 857-881
    • Gundersen, H.J.1    Bagger, P.2    Bendtsen, T.F.3    Evans, S.M.4    Korbo, L.5    Marcussen, N.6
  • 15
    • 0019775106 scopus 로고
    • Simultaneous quantification of dopamine, 5-hydroxytryptamine and four metabolically related compounds by means of reversed-phase high-performance liquid chromatography with electrochemical detection
    • Kilts C.D., Breese G.R., Mailman R.B. Simultaneous quantification of dopamine, 5-hydroxytryptamine and four metabolically related compounds by means of reversed-phase high-performance liquid chromatography with electrochemical detection. J Chromatogr 1981, 225:347-357.
    • (1981) J Chromatogr , vol.225 , pp. 347-357
    • Kilts, C.D.1    Breese, G.R.2    Mailman, R.B.3
  • 16
    • 0032143368 scopus 로고    scopus 로고
    • Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
    • Kirik D., Rosenblad C., Björklund A. Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp Neurol 1998, 152:259-277.
    • (1998) Exp Neurol , vol.152 , pp. 259-277
    • Kirik, D.1    Rosenblad, C.2    Björklund, A.3
  • 17
    • 0016143121 scopus 로고
    • Pharmacological actions of 6-hydroxydopamine
    • Kostrzewa R.M., Jacobowitz D.M. Pharmacological actions of 6-hydroxydopamine. Pharmacol Rev 1974, 26:199-288.
    • (1974) Pharmacol Rev , vol.26 , pp. 199-288
    • Kostrzewa, R.M.1    Jacobowitz, D.M.2
  • 18
    • 0018214422 scopus 로고
    • Metabolism of amphetamine after acute and chronic administration to the rat
    • Kuhn C.M., Schanberg S.M. Metabolism of amphetamine after acute and chronic administration to the rat. J Pharmacol Exp Ther 1978, 207:544-554.
    • (1978) J Pharmacol Exp Ther , vol.207 , pp. 544-554
    • Kuhn, C.M.1    Schanberg, S.M.2
  • 19
    • 0029981267 scopus 로고    scopus 로고
    • Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat
    • Lee C.S., Sauer H., Bjorklund A. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience 1996, 72:641-653.
    • (1996) Neuroscience , vol.72 , pp. 641-653
    • Lee, C.S.1    Sauer, H.2    Bjorklund, A.3
  • 20
    • 51249101075 scopus 로고    scopus 로고
    • Decreased brain docosahexaenoic acid content produces neurobiological effects associated with depression: interactions with reproductive status in female rats
    • Levant B., Ozias M.K., Davis P.F., Winter M., Russell K.L., Carlson S.E., et al. Decreased brain docosahexaenoic acid content produces neurobiological effects associated with depression: interactions with reproductive status in female rats. Psychoneuroendocrinology 2008, 33:1279-1292.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 1279-1292
    • Levant, B.1    Ozias, M.K.2    Davis, P.F.3    Winter, M.4    Russell, K.L.5    Carlson, S.E.6
  • 21
    • 79953001974 scopus 로고    scopus 로고
    • Differences in methylphenidate dose response between periadolescent and adult rats in the familiar arena-novel alcove task
    • Levant B., Zarcone T.J., Davis P.F., Ozias M.K., Fowler S.C. Differences in methylphenidate dose response between periadolescent and adult rats in the familiar arena-novel alcove task. J Pharmacol Exp Ther 2011, 337:83-91.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 83-91
    • Levant, B.1    Zarcone, T.J.2    Davis, P.F.3    Ozias, M.K.4    Fowler, S.C.5
  • 22
    • 0033049711 scopus 로고    scopus 로고
    • Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats
    • Lindner M.D., Cain C.K., Plone M.A., Frydel B.R., Blaney T.J., Emerich D.F., et al. Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats. Behav Brain Res 1999, 102:1-16.
    • (1999) Behav Brain Res , vol.102 , pp. 1-16
    • Lindner, M.D.1    Cain, C.K.2    Plone, M.A.3    Frydel, B.R.4    Blaney, T.J.5    Emerich, D.F.6
  • 23
    • 0025232430 scopus 로고
    • Parkinson's disease
    • Marsden C.D. Parkinson's disease. Lancet 1990, 335:948-952.
    • (1990) Lancet , vol.335 , pp. 948-952
    • Marsden, C.D.1
  • 26
    • 0035020470 scopus 로고    scopus 로고
    • Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: similarities with cell loss in parkinson's disease
    • Rodríguez M., Barroso-Chinea P., Abdala P., Obeso J., González-Hernández T. Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: similarities with cell loss in parkinson's disease. Exp Neurol 2001, 169:163-181.
    • (2001) Exp Neurol , vol.169 , pp. 163-181
    • Rodríguez, M.1    Barroso-Chinea, P.2    Abdala, P.3    Obeso, J.4    González-Hernández, T.5
  • 28
    • 0028220834 scopus 로고
    • Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat
    • Sauer H., Oertel W.H. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 1994, 59:401-415.
    • (1994) Neuroscience , vol.59 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 29
    • 11844300345 scopus 로고    scopus 로고
    • Design-based stereology in neuroscience
    • Schmitz C., Hof P.R. Design-based stereology in neuroscience. Neuroscience 2005, 130:813-831.
    • (2005) Neuroscience , vol.130 , pp. 813-831
    • Schmitz, C.1    Hof, P.R.2
  • 30
    • 5444238860 scopus 로고    scopus 로고
    • Histological changes of the dopaminergic nigrostriatal system in aging
    • Stark A.K., Pakkenberg B. Histological changes of the dopaminergic nigrostriatal system in aging. Cell Tissue Res 2004, 318:81-92.
    • (2004) Cell Tissue Res , vol.318 , pp. 81-92
    • Stark, A.K.1    Pakkenberg, B.2
  • 31
    • 0021234096 scopus 로고
    • The unbiased estimation of number and sizes of arbitrary particles using the disector
    • Sterio D.C. The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 1984, 134:127-136.
    • (1984) J Microsc , vol.134 , pp. 127-136
    • Sterio, D.C.1
  • 32
    • 84866154689 scopus 로고    scopus 로고
    • Modification of AgNOR staining to reveal the nucleolus in thick sections specified for stereological assessment of dopaminergic neurotoxicity in substantia nigra, pars compacta
    • 2011 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. Online
    • Switzer R.C., Baun J., Tipton B., Segovia C., Ahmad S.O., Benkovic S.A. Modification of AgNOR staining to reveal the nucleolus in thick sections specified for stereological assessment of dopaminergic neurotoxicity in substantia nigra, pars compacta. Soc Neurosci Abst 2011, 304-305. 2011 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. Online.
    • (2011) Soc Neurosci Abst , pp. 304-305
    • Switzer, R.C.1    Baun, J.2    Tipton, B.3    Segovia, C.4    Ahmad, S.O.5    Benkovic, S.A.6
  • 33
    • 0034174667 scopus 로고    scopus 로고
    • AgNOR staining and quantification
    • Trerè D. AgNOR staining and quantification. Micron 2000, 31:127-131.
    • (2000) Micron , vol.31 , pp. 127-131
    • Trerè, D.1
  • 34
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt U., Arbuthnott G.W. Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. Brain Res 1970, 24:485-493.
    • (1970) Brain Res , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2
  • 35
    • 0027194462 scopus 로고
    • New stereological methods for counting neurons
    • West M.J. New stereological methods for counting neurons. Neurobiol Aging 1993, 14:275-285.
    • (1993) Neurobiol Aging , vol.14 , pp. 275-285
    • West, M.J.1


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