Clinical and quantitative pathologic correlates of dementia with Lewy bodies

Neurology

Volumn 53, Issue 6, 1999, Pages 1284-1291

  Gomez Tortosa E ^a   Newell, K ^a   Irizarry, M C ^a   Albert, M ^a   Growdon, J H ^a   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

AD; Dementia; Lewy bodies

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN BIOPSY; CLINICAL ARTICLE; CLINICAL FEATURE; COGNITIVE DEFECT; DELUSION; DISEASE SEVERITY; FALLING; FEMALE; HISTOPATHOLOGY; HUMAN; LEWY BODY; MALE; NEUROFIBRILLARY TANGLE; PARKINSONISM; PRIORITY JOURNAL; VISUAL HALLUCINATION;

EID: 0344898557     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.53.6.1284     Document Type: Article

References (49)

1. Gibb W, Esiri M, Lees A. Clinical and pathological features of diffuse cortical Lewy body disease (Lewy body dementia). Brain 1987;110:1131-1153.
2. Perry R, Irving D, Blessed G, Fairbairn A, Perry E. Senile dementia of Lewy body type: a clinically and neuropathologically distinct form of Lewy body dementia in the elderly. J Neurol Sci 1990;95:119-139.
3. Hansen L, Salmon D, Galasko D, et al. The Lewy body variant of Alzheimer's disease: a clinical and pathological entity. Neurology 1990;40:1-8.
4. Kosaka K. Dementia and neuropathology in Lewy body disease. Adv Neurol 1993;60:456-463.
5. Galasko D, Katzman R, Salmon DP, Hansen L. Clinical and neuropathological findings in Lewy body dementias. Brain Cogn 1996;31:166-175.
6. Gómez-Tortosa E, Ingraham AO, Irizarry MC, Hyman BT. Dementia with Lewy bodies. J Am Geriatr Soc 1998;46:1449-1458.
7. McKeith I, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop. Neurology 1996;47:1113-1124.
8. Hughes AJ. Clinicopathological aspects of Parkinson's disease. Eur Neurol 1997;38(suppl 2):13-20.
9. Wakabayashi K, Hansen LA, Masliah E. Cortical Lewy body-containing neurons are pyramidal cells: laser confocal imaging of double-immunolabeled sections with anti-ubiquitin and SMI32. Acta Neuropathol (Berl) 1995;89:404-408.
10. Lippa CF, Smith TW, Swearer JM. Alzheimer's disease and Lewy body disease: a comparative clinicopathological study. Ann Neurol 1994;35:81-88.
11. Gómez-Isla T, Growdon W, McNamara M, Growdon JH, Hyman BT. Diffuse Lewy body dementia: quantitative neuropathological studies and APOE genotyping. Neurology 1997; 48(suppl):140-141.
12. Schmidt M, Murray J, Lee VM-Y, Hill W, Wertkin A, Trojanowski JQ. Epitope map of neurofilament protein domains of each neurofilament subunit are present in Parkinson's disease Lewy bodies. Am J Pathol 1991;139:53-65.
13. Spillantini M, Schmidt M, Lee VM-Y, Trojanowski JQ, Jakes R, Goedert M. α-Synuclein in Lewy bodies. Nature 1997;388: 839-840.
14. Irizarry M, Growdon W, Gómez-Isla T, et al. Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity. J Neuropathol Exp Neurol 1998;57:334-337.
15. Trojanowski JQ, Lee VM-Y. Aggregation of neurofilament and α-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia. Arch Neurol 1998;55:151-152.
16. Heintz N, Zoghbi H. α-Synuclein: a link between Parkinson and Alzheimer diseases? Nat Genet 1997;16:325-327.
17. Dickson D, Crystal H, Mattiace L, et al. Diffuse Lewy body disease- light and electron microscopic immunocytochemistry of senile plaques. Acta Neuropathol (Berl) 1989;78:572-584.
18. Hansen L, Masliah E, Galasko D, Terry R. Plaque-only Alzheimer disease is usually the Lewy body variant, and vice versa. J Neuropathol Exp Neurol 1993;52:648-654.
19. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 3rd ed. Revised. Washington, DC: American Psychiatric Association, 1987.
20. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968; 114:797-811.
21. Locascio J, Growdon JH, Corkin S. Cognitive test performance in detecting, staging, and tracking Alzheimer's disease. Arch Neurol 1995;52:1087-1099.
22. Parkinson Study Group. DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Arch Neurol 1989; 46:1052-1060.
23. Vonsattel JP, Aizawa H, Ge P, et al. An improved approach to prepare human brains for research. J Neuropathol Exp Neurol 1995;54:42-56.
24. Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:239-259.
25. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. Neurobiol Aging 1997;18(suppl 4):S1-S2.
26. Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486.
27. Albin RL, Minoshima S, D'Amato CJ, Frey KA, Kuhl DA, Sima AAF. Fluoro-deoxyglucose positron emission tomography in diffuse Lewy body disease. Neurology 1996;47:462-466.
28. Ishii K, Imamura T, Sasaki M, et al. Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer's disease. Neurology 1998;51:125-130.
29. Salmon DP, Galasko D, Hansen LA, et al. Neuropsychological deficits associated with diffuse Lewy body disease. Brain Cogn 1996;31:148-165.
30. Takeda A, Mallory M, Sundsmo M, Honer W, Hansen L, Masliah E. Abnormal accumulation of NACP/α-synuclein in neurodegenerative disorders. Am J Pathol 1998;152:367-372.
31. Hughes AJ, Daniel SE, Blankson S, Lees AJ. A clinicopathological study of 100 cases of Parkinson's disease. Arch Neurol 1993;50:140-148.
32. Förstl H, Burns A, Luthert P, Cairns N, Levy R. The Lewy-body variant of Alzheimer's disease: clinical and pathological findings. Br J Psychiatry 1993;162:385-392.
33. Crystal H, Dickson D, Lizardi J, Davies P, Wolfson L. Antemortem diagnosis of diffuse Lewy body disease. Neurology 1990;40:1523-1528.
34. Dickson DW, Crystal H, Davies P, Hardy J. Cytoskeletal and Alzheimer-type pathology in Lewy body disease. In: Perry R, McKeith I, Perry E, eds. Dementia with Lewy bodies: clinical, pathological and treatment issues. Cambridge, UK: Cambridge University Press, 1996:224-237.
35. Armstrong R, Cairns N, Lantos P. β-Amyloid (Aβ) deposition in the medial temporal lobe of patients with dementia with Lewy bodies. Neurosci Lett 1997;227:193-196.
36. Gómez-Isla T, Hollister R, West H, et al. Neuronal loss correlates but exceeds neurofibrillary tangles in Alzheimer's disease. Ann Neurol 1997;41:17-24.
37. Byrne E, Lennox G, Lowe J, Godwin-Austen R. Diffuse Lewy body disease: clinical features in 15 cases. J Neurol Neurosurg Psychiatry 1989;52:709-717.
38. Kuzuhara S, Yoshimura M, Mizutani T, Yamanouchi H, Ihara Y. Clinical features of diffuse Lewy body disease in the elderly: analysis of 12 cases. In: Perry R, McKeith I, Perry E, eds. Dementia with Lewy bodies: clinical, pathological and treatment issues. Cambridge, UK: Cambridge University Press, 1996:153-160.
39. Collerton D, Davies C, Thompson P. Lewy body dementia in clinical practice. In: Perry R, McKeith I, Perry E, eds. Dementia with Lewy bodies: clinical, pathological and treatment issues. Cambridge, UK: Cambridge University Press, 1996:171-186.
40. Burkhardt C, Filley C, Kleinschmidt-DeMasters B, de la Monte S, Norenberg M, Schneck S. Diffuse Lewy body disease and progressive dementia. Neurology 1988;38:1520-1528.
41. Klatka LA, Louis ED, Schiffer RB. Psychiatric features in diffuse Lewy body disease: a clinicopathologic study using Alzheimer's disease and Parkinson's disease comparison groups. Neurology 1996;47:1148-1152.
42. Louis ED, Klatka LA, Liu Y, Fahn S. Comparison of extrapyramidal features in 31 pathologically confirmed cases of diffuse Lewy body disease and 34 pathologically confirmed cases of Parkinson's disease. Neurology 1997;48:376-380.
43. Perry R, Jaros E, Irving D, et al. What is the neuropathological basis of dementia associated with Lewy bodies? In: Perry R, McKeith I, Perry E, eds. Dementia with Lewy bodies: clinical, pathological and treatment issues. Cambridge, UK: Cambridge University Press, 1996:212-223.
44. Gómez-Isla T, Growdon WB, McNamara M, Gömez-Tortosa E, Hedley-Whyte ET, Hyman BT. Clincopathological correlates in temporal cortex in dementia with Lewy bodies. Neurology 1999 (in press).
45. Churchyard A, Lees AJ. The relationship between dementia and direct involvement of the hippocampus and amygdala in Parkinson's disease. Neurology 1997;49:1570-1576.
46. Lennox G, Lowe J, Landon M, Byrne EJ, Mayer RJ, Godwin-Austen RB. Diffuse Lewy body disease: correlative neuropathology using anti-ubiquitin immunocytochemistry. J Neurol Neurosurg Psychiatry 1989;52:1236-1247.
47. Samuel W, Galasko D, Masliah E, Hansen LA. Neocortical Lewy body counts correlate with dementia in the Lewy body variant of Alzheimer's disease. J Neuropathol Exp Neurol 1996;55:44-52.
48. Samuel W, Alford M, Hofstetter CR, Hansen L. Dementia with Lewy bodies versus pure Alzheimer disease: differences in cognition, neuropathology, cholinergic dysfunction, and synapse density. J Neuropathol Exp Neurol 1997;56:499-508.
49. Mattila PM, Röyttä M, Torikka H, Dickson DW, Rinne JO. Cortical Lewy bodies and Alzheimer-type changes in patients with Parkinson's disease. Acta Neuropathol (Berl) 1998;95: 576-582.