Cyclin e deregulation promotes loss of specific genomic regions

Current Biology

Volumn 25, Issue 10, 2015, Pages 1327-1333

  Teixeira, Leonardo K ^a   Wang, Xianlong ^b   Li, Yongjiang ^a   Ekholm Reed, Susanna ^a   Wu, Xiaohua ^a   Wang, Pei ^b   Reed, Steven I ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUS MUSCULUS;

BCR PROTEIN, HUMAN; BREAKPOINT CLUSTER REGION PROTEIN; CCNE1 PROTEIN, HUMAN; CYCLIN E; HISTONE LYSINE METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; MLL PROTEIN, HUMAN; ONCOPROTEIN;

ANAPHASE; BREAST TUMOR; DNA REPLICATION; EPITHELIUM CELL; FEMALE; GENE LOCUS; GENETICS; GENOMIC INSTABILITY; HUMAN; METABOLISM; MITOSIS; MULTIGENE FAMILY; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANAPHASE; BREAST NEOPLASMS; CELL LINE, TUMOR; CYCLIN E; DNA REPLICATION; EPITHELIAL CELLS; FEMALE; GENETIC LOCI; GENOMIC INSTABILITY; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; MITOSIS; MULTIGENE FAMILY; MYELOID-LYMPHOID LEUKEMIA PROTEIN; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCR;

EID: 84929607476     PISSN: 09609822     EISSN: 18790445     Source Type: Journal    
DOI: 10.1016/j.cub.2015.03.022     Document Type: Article

References (36)

1. M. Malumbres, and M. Barbacid Cell cycle, CDKs and cancer: a changing paradigm Nat. Rev. Cancer 9 2009 153 166
2. H.C. Hwang, and B.E. Clurman Cyclin E in normal and neoplastic cell cycles Oncogene 24 2005 2776 2786
3. S. Ekholm-Reed, J. Méndez, D. Tedesco, A. Zetterberg, B. Stillman, and S.I. Reed Deregulation of cyclin E in human cells interferes with prereplication complex assembly J. Cell Biol. 165 2004 789 800
4. J. Bartkova, N. Rezaei, M. Liontos, P. Karakaidos, D. Kletsas, N. Issaeva, L.V. Vassiliou, E. Kolettas, K. Niforou, and V.C. Zoumpourlis Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints Nature 444 2006 633 637
5. C.H. Spruck, K.A. Won, and S.I. Reed Deregulated cyclin E induces chromosome instability Nature 401 1999 297 300
6. Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients Nat. Med. 3 1997 222 225
7. K. Keyomarsi, S.L. Tucker, T.A. Buchholz, M. Callister, Y. Ding, G.N. Hortobagyi, I. Bedrosian, C. Knickerbocker, W. Toyofuku, and M. Lowe Cyclin E and survival in patients with breast cancer N. Engl. J. Med. 347 2002 1566 1575
8. D.M. Bortner, and M.P. Rosenberg Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E Mol. Cell. Biol. 17 1997 453 459
9. V. Liberal, H.-S. Martinsson-Ahlzén, J. Liberal, C.H. Spruck, M. Widschwendter, C.H. McGowan, and S.I. Reed Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins Proc. Natl. Acad. Sci. USA 109 2012 2754 2759
10. A.C. Bester, M. Roniger, Y.S. Oren, M.M. Im, D. Sarni, M. Chaoat, A. Bensimon, G. Zamir, D.S. Shewach, and B. Kerem Nucleotide deficiency promotes genomic instability in early stages of cancer development Cell 145 2011 435 446
11. K.J. Neelsen, I.M. Zanini, R. Herrador, and M. Lopes Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates J. Cell Biol. 200 2013 699 708
12. K. Keyomarsi, and A.B. Pardee Redundant cyclin overexpression and gene amplification in breast cancer cells Proc. Natl. Acad. Sci. USA 90 1993 1112 1116
13. H. Strohmaier, C.H. Spruck, P. Kaiser, K.A. Won, O. Sangfelt, and S.I. Reed Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line Nature 413 2001 316 322
14. K.L. Chan, T. Palmai-Pallag, S. Ying, and I.D. Hickson Replication stress induces sister-chromatid bridging at fragile site loci in mitosis Nat. Cell Biol. 11 2009 753 760
15. V. Naim, and F. Rosselli The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities Nat. Cell Biol. 11 2009 761 768
16. T. Kawabata, S.W. Luebben, S. Yamaguchi, I. Ilves, I. Matise, T. Buske, M.R. Botchan, and N. Shima Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression Mol. Cell 41 2011 543 553
17. N. Weddington, A. Stuy, I. Hiratani, T. Ryba, T. Yokochi, and D.M. Gilbert ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data BMC Bioinformatics 9 2008 530
18. C. Curtis, S.P. Shah, S.F. Chin, G. Turashvili, O.M. Rueda, M.J. Dunning, D. Speed, A.G. Lynch, S. Samarajiwa, Y. Yuan METABRIC Group The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups Nature 486 2012 346 352
19. A.G. Muntean, and J.L. Hess The pathogenesis of mixed-lineage leukemia Annu. Rev. Pathol. 7 2012 283 301
20. L. Costantino, S.K. Sotiriou, J.K. Rantala, S. Magin, E. Mladenov, T. Helleday, J.E. Haber, G. Iliakis, O.P. Kallioniemi, and T.D. Halazonetis Break-induced replication repair of damaged forks induces genomic duplications in human cells Science 343 2014 88 91
21. A. Letessier, G.A. Millot, S. Koundrioukoff, A.M. Lachagès, N. Vogt, R.S. Hansen, B. Malfoy, O. Brison, and M. Debatisse Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site Nature 470 2011 120 123
22. J.J. Blow, and P.J. Gillespie Replication licensing and cancer - a fatal entanglement? Nat. Rev. Cancer 8 2008 799 806
23. M.M. Martin, M. Ryan, R. Kim, A.L. Zakas, H. Fu, C.M. Lin, W.C. Reinhold, S.R. Davis, S. Bilke, and H. Liu Genome-wide depletion of replication initiation events in highly transcribed regions Genome Res. 21 2011 1822 1832
24. G.I. Dellino, D. Cittaro, R. Piccioni, L. Luzi, S. Banfi, S. Segalla, M. Cesaroni, R. Mendoza-Maldonado, M. Giacca, and P.G. Pelicci Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing Genome Res. 23 2013 1 11
25. E. Ozeri-Galai, R. Lebofsky, A. Rahat, A.C. Bester, A. Bensimon, and B. Kerem Failure of origin activation in response to fork stalling leads to chromosomal instability at fragile sites Mol. Cell 43 2011 122 131
26. J. Bartkova, Z. Horejsí, K. Koed, A. Krämer, F. Tort, K. Zieger, P. Guldberg, M. Sehested, J.M. Nesland, and C. Lukas DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Nature 434 2005 864 870
27. V.G. Gorgoulis, L.V. Vassiliou, P. Karakaidos, P. Zacharatos, A. Kotsinas, T. Liloglou, M. Venere, R.A. Ditullio Jr., N.G. Kastrinakis, and B. Levy Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Nature 434 2005 907 913
28. R. Di Micco, M. Fumagalli, A. Cicalese, S. Piccinin, P. Gasparini, C. Luise, C. Schurra, M. Garre', P.G. Nuciforo, and A. Bensimon Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication Nature 444 2006 638 642
29. R.A. Burrell, S.E. McClelland, D. Endesfelder, P. Groth, M.C. Weller, N. Shaikh, E. Domingo, N. Kanu, S.M. Dewhurst, and E. Gronroos Replication stress links structural and numerical cancer chromosomal instability Nature 494 2013 492 496
30. S.A. Hills, and J.F.X. Diffley DNA replication and oncogene-induced replicative stress Curr. Biol. 24 2014 R435 R444
31. A.M. Casper, P. Nghiem, M.F. Arlt, and T.W. Glover ATR regulates fragile site stability Cell 111 2002 779 789
32. S.G. Durkin, and T.W. Glover Chromosome fragile sites Annu. Rev. Genet. 41 2007 169 192
33. M. Debatisse, B. Le Tallec, A. Letessier, B. Dutrillaux, and O. Brison Common fragile sites: mechanisms of instability revisited Trends Genet. 28 2012 22 32
34. E. Ozeri-Galai, A.C. Bester, and B. Kerem The complex basis underlying common fragile site instability in cancer Trends Genet. 28 2012 295 302
35. M. Negrini, C.A. Felix, C. Martin, B.J. Lange, T. Nakamura, E. Canaani, and C.M. Croce Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia Cancer Res. 53 1993 4489 4492
36. B. Accordi, V. Espina, M. Giordan, A. VanMeter, G. Milani, L. Galla, M. Ruzzene, M. Sciro, L. Trentin, and R. De Maria Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL PLoS ONE 5 2010 e13552