Altered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease

Journal of Hepatology

Volumn 61, Issue 5, 2014, Pages 1115-1125

  Pereira Fantini, Prue M ^a   Lapthorne, Susan ^a   Joyce, Susan A ^b   Dellios, Nicole L ^a   Wilson, Guineva ^a,c   Fouhy, Fiona ^d,e   Thomas, Sarah L ^a   Scurr, Michelle ^a   Hill, Colin ^b   Gahan, Cormac G M ^b   Cotter, Paul D ^b,e   Fuller, Peter J ^f   Hardikar, Winita ^a,g,h   Bines, Julie E ^a,g  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c MONASH MEDICAL CENTRE   (Australia)

^d UNIVERSITY COLLEGE CORK   (Ireland)

^e TEAGASC FOOD RESEARCH CENTRE   (Ireland)

^f HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

^h MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

Author keywords

Bile acids and salts; Farnesoid X receptor NR1H4; Gut microbiota; Intestinal failure associated liver disease; Liver diseases; Short bowel syndrome

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; FARNESOID X RECEPTOR; FAT DROPLET; FIBROBLAST GROWTH FACTOR 19; HETERODIMER; HYDROLASE; HYODEOXYCHOLIC ACID; LITHOCHOLIC ACID; URSODEOXYCHOLIC ACID; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEROIDES; BIFIDOBACTERIUM; BILE ACID METABOLISM; BILE ACID SYNTHESIS; BIOINFORMATICS; BIOTRANSFORMATION; CLOSTRIDIUM; CONTROLLED STUDY; DIARRHEA; DISEASE ASSOCIATION; DYSBIOSIS; EUBACTERIUM; FECES COMPOSITION; FEMALE; GENE EXPRESSION; HEPATITIS; HIGH THROUGHPUT SEQUENCING; INTESTINE FLORA; LACTOBACILLUS; LIVER CELL; LIVER DISEASE; LIVER FIBROSIS; LIVER HISTOLOGY; LIVER INJURY; LIVER MITOCHONDRION; METABOLIC DISORDER; NONHUMAN; PIGLET; PRIORITY JOURNAL; SHAM PROCEDURE; SHORT BOWEL SYNDROME; SIGNAL TRANSDUCTION; SMALL INTESTINE RESECTION; STEATORRHEA; ANIMAL; COMPLICATION; DISEASE MODEL; HUMAN; LIVER; LIVER DISEASES; METABOLISM; MICROBIOLOGY; MICROFLORA; PATHOLOGY; PIG;

ANIMALS; BILE ACIDS AND SALTS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; LIVER; LIVER DISEASES; MICROBIOTA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SHORT BOWEL SYNDROME; SIGNAL TRANSDUCTION; SUS SCROFA;

EID: 84929606430     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.06.025     Document Type: Article

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