Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 20, 2015, Pages E2667-E2676

  Leopold, Luciana E ^a   Heestand, Bree N ^a,b   Seong, Soobin ^a   Shtessel, Ludmila ^a   Ahmed, Shawn ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Epigenetics; Epigenome; RNAe; siRNAs; Transgenerational silencing

Indexed keywords

EPITOPE; GENOMIC DNA; MESSENGER RNA; PIWI INTERACTING RNA; SMALL INTERFERING RNA; TELOMERE BINDING PROTEIN; ABC TRANSPORTER; ARGONAUTE PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; PRG-1 PROTEIN, C ELEGANS; PRIMER DNA; RDE-2 PROTEIN, C ELEGANS; RED FLUORESCENT PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CHROMATIN; CHROMOSOME 2; CHROMOSOME 3; CHROMOSOME 5; CHROMOSOME PAIRING; CONTROLLED STUDY; CRISPR CAS SYSTEM; FLUORESCENCE; GENE CONVERSION; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; GERM CELL; HEMIZYGOTE; HETEROZYGOTE; HOMOZYGOTE; MOLECULAR SENSOR; NONHUMAN; PRIORITY JOURNAL; PROGENY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSGENE; TRANSGENE EXPRESSION; TRANSGENE SILENCING; TRANSPOSON; ZINC FINGER MOTIF; ANIMAL; FLUORESCENCE MICROSCOPY; GENETICS; INTERFERENCE MICROSCOPY; MEIOSIS; METABOLISM; PHYSIOLOGY;

CAENORHABDITIS ELEGANS;

ANIMALS; ARGONAUTE PROTEINS; ATP-BINDING CASSETTE TRANSPORTERS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA PRIMERS; GENE SILENCING; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MEIOSIS; MICROSCOPY, FLUORESCENCE; MICROSCOPY, INTERFERENCE; RNA, SMALL INTERFERING; TRANSGENES;

EID: 84929598529     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501979112     Document Type: Article

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