메뉴 건너뛰기




Volumn 8, Issue 7, 2012, Pages

Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; PIWI INTERACTING RNA; PROTEIN HEN1; PROTEIN HENN 1; RNA; RNA 21U; RNA 26G; RNA METHYLTRANSFERASE; UNCLASSIFIED DRUG;

EID: 84860588377     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002702     Document Type: Article
Times cited : (80)

References (59)
  • 1
    • 60149098474 scopus 로고    scopus 로고
    • Small RNAs as guardians of the genome
    • Malone CD, Hannon GJ, (2009) Small RNAs as guardians of the genome. Cell 136: 656-668.
    • (2009) Cell , vol.136 , pp. 656-668
    • Malone, C.D.1    Hannon, G.J.2
  • 2
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: an expanding universe
    • Ghildiyal M, Zamore PD, (2009) Small silencing RNAs: an expanding universe. Nat Rev Genet 10: 94-108.
    • (2009) Nat Rev Genet , vol.10 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 3
    • 78149476037 scopus 로고    scopus 로고
    • Small RNA-mediated quiescence of transposable elements in animals
    • Saito K, Siomi MC, (2010) Small RNA-mediated quiescence of transposable elements in animals. Dev Cell 19: 687-697.
    • (2010) Dev Cell , vol.19 , pp. 687-697
    • Saito, K.1    Siomi, M.C.2
  • 4
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 5
    • 79751485564 scopus 로고    scopus 로고
    • The many faces of RNAi
    • Ketting RF, (2011) The many faces of RNAi. Developmental cell 20: 148-161.
    • (2011) Developmental Cell , vol.20 , pp. 148-161
    • Ketting, R.F.1
  • 6
    • 37549014207 scopus 로고    scopus 로고
    • Argonaute proteins: key players in RNA silencing
    • Hutvagner G, Simard MJ, (2008) Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol 9: 22-32.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 22-32
    • Hutvagner, G.1    Simard, M.J.2
  • 7
    • 77953140972 scopus 로고    scopus 로고
    • Argonaute proteins at a glance
    • Ender C, Meister G, (2010) Argonaute proteins at a glance. J Cell Sci 123: 1819-1823.
    • (2010) J Cell Sci , vol.123 , pp. 1819-1823
    • Ender, C.1    Meister, G.2
  • 8
    • 77955290050 scopus 로고    scopus 로고
    • Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production
    • Miyoshi K, Miyoshi T, Siomi H, (2010) Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production. Molecular genetics and genomics: MGG 284: 95-103.
    • (2010) Molecular Genetics and Genomics: MGG , vol.284 , pp. 95-103
    • Miyoshi, K.1    Miyoshi, T.2    Siomi, H.3
  • 9
    • 33846527241 scopus 로고    scopus 로고
    • Distinct populations of primary and secondary effectors during RNAi in C. elegans
    • Pak J, Fire A, (2007) Distinct populations of primary and secondary effectors during RNAi in C. elegans. Science 315: 241-244.
    • (2007) Science , vol.315 , pp. 241-244
    • Pak, J.1    Fire, A.2
  • 10
    • 33846524902 scopus 로고    scopus 로고
    • Secondary siRNAs result from unprimed RNA synthesis and form a distinct class
    • Sijen T, Steiner FA, Thijssen KL, Plasterk RH, (2007) Secondary siRNAs result from unprimed RNA synthesis and form a distinct class. Science 315: 244-247.
    • (2007) Science , vol.315 , pp. 244-247
    • Sijen, T.1    Steiner, F.A.2    Thijssen, K.L.3    Plasterk, R.H.4
  • 11
    • 37149049127 scopus 로고    scopus 로고
    • In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans
    • Aoki K, Moriguchi H, Yoshioka T, Okawa K, Tabara H, (2007) In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans. EMBO J 26: 5007-5019.
    • (2007) EMBO J , vol.26 , pp. 5007-5019
    • Aoki, K.1    Moriguchi, H.2    Yoshioka, T.3    Okawa, K.4    Tabara, H.5
  • 12
    • 13644256193 scopus 로고    scopus 로고
    • Methylation as a crucial step in plant microRNA biogenesis
    • Yu B, Yang Z, Li J, Minakhina S, Yang M, et al. (2005) Methylation as a crucial step in plant microRNA biogenesis. Science 307: 932-935.
    • (2005) Science , vol.307 , pp. 932-935
    • Yu, B.1    Yang, Z.2    Li, J.3    Minakhina, S.4    Yang, M.5
  • 13
    • 34447291602 scopus 로고    scopus 로고
    • The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC
    • Horwich MD, Li C, Matranga C, Vagin V, Farley G, et al. (2007) The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol 17: 1265-1272.
    • (2007) Curr Biol , vol.17 , pp. 1265-1272
    • Horwich, M.D.1    Li, C.2    Matranga, C.3    Vagin, V.4    Farley, G.5
  • 14
    • 34347378274 scopus 로고    scopus 로고
    • Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi- interacting RNAs at their 3′ ends
    • Saito K, Sakaguchi Y, Suzuki T, Siomi H, Siomi MC, (2007) Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi- interacting RNAs at their 3′ ends. Genes Dev 21: 1603-1608.
    • (2007) Genes Dev , vol.21 , pp. 1603-1608
    • Saito, K.1    Sakaguchi, Y.2    Suzuki, T.3    Siomi, H.4    Siomi, M.C.5
  • 15
    • 34548366485 scopus 로고    scopus 로고
    • The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs
    • Kirino Y, Mourelatos Z, (2007) The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs. RNA 13: 1397-1401.
    • (2007) RNA , vol.13 , pp. 1397-1401
    • Kirino, Y.1    Mourelatos, Z.2
  • 16
    • 62549159996 scopus 로고    scopus 로고
    • 2′-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena
    • Kurth HM, Mochizuki K, (2009) 2′-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena. RNA 15: 675-685.
    • (2009) RNA , vol.15 , pp. 675-685
    • Kurth, H.M.1    Mochizuki, K.2
  • 18
    • 80052991624 scopus 로고    scopus 로고
    • 3′ End Formation of PIWI-Interacting RNAs In Vitro
    • Kawaoka S, Izumi N, Katsuma S, Tomari Y, (2011) 3′ End Formation of PIWI-Interacting RNAs In Vitro. Molecular cell 43: 1015-1022.
    • (2011) Molecular Cell , vol.43 , pp. 1015-1022
    • Kawaoka, S.1    Izumi, N.2    Katsuma, S.3    Tomari, Y.4
  • 19
    • 77953801618 scopus 로고    scopus 로고
    • Target RNA-directed trimming and tailing of small silencing RNAs
    • Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, et al. (2010) Target RNA-directed trimming and tailing of small silencing RNAs. Science 328: 1534-1539.
    • (2010) Science , vol.328 , pp. 1534-1539
    • Ameres, S.L.1    Horwich, M.D.2    Hung, J.H.3    Xu, J.4    Ghildiyal, M.5
  • 21
    • 23944493378 scopus 로고    scopus 로고
    • Methylation protects miRNAs and siRNAs from a 3′-end uridylation activity in Arabidopsis
    • Li J, Yang Z, Yu B, Liu J, Chen X, (2005) Methylation protects miRNAs and siRNAs from a 3′-end uridylation activity in Arabidopsis. Curr Biol 15: 1501-1507.
    • (2005) Curr Biol , vol.15 , pp. 1501-1507
    • Li, J.1    Yang, Z.2    Yu, B.3    Liu, J.4    Chen, X.5
  • 22
    • 70349442298 scopus 로고    scopus 로고
    • CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs
    • van Wolfswinkel JC, Claycomb JM, Batista PJ, Mello CC, Berezikov E, et al. (2009) CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs. Cell 139: 135-148.
    • (2009) Cell , vol.139 , pp. 135-148
    • van Wolfswinkel, J.C.1    Claycomb, J.M.2    Batista, P.J.3    Mello, C.C.4    Berezikov, E.5
  • 23
    • 77649249858 scopus 로고    scopus 로고
    • Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway
    • Vasale JJ, Gu W, Thivierge C, Batista PJ, Claycomb JM, et al. (2010) Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway. Proc Natl Acad Sci U S A 107: 3582-3587.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 3582-3587
    • Vasale, J.J.1    Gu, W.2    Thivierge, C.3    Batista, P.J.4    Claycomb, J.M.5
  • 24
    • 73249136094 scopus 로고    scopus 로고
    • 26G endo-siRNAs regulate spermatogenic and zygotic gene expression in Caenorhabditis elegans
    • Han T, Manoharan AP, Harkins TT, Bouffard P, Fitzpatrick C, et al. (2009) 26G endo-siRNAs regulate spermatogenic and zygotic gene expression in Caenorhabditis elegans. Proc Natl Acad Sci U S A 106: 18674-18679.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18674-18679
    • Han, T.1    Manoharan, A.P.2    Harkins, T.T.3    Bouffard, P.4    Fitzpatrick, C.5
  • 25
    • 77649254581 scopus 로고    scopus 로고
    • Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans
    • Conine CC, Batista PJ, Gu W, Claycomb JM, Chaves DA, et al. (2010) Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A 107: 3588-3593.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 3588-3593
    • Conine, C.C.1    Batista, P.J.2    Gu, W.3    Claycomb, J.M.4    Chaves, D.A.5
  • 26
    • 71549139424 scopus 로고    scopus 로고
    • A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference
    • Gent JI, Schvarzstein M, Villeneuve AM, Gu SG, Jantsch V, et al. (2009) A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference. Genetics 183: 1297-1314.
    • (2009) Genetics , vol.183 , pp. 1297-1314
    • Gent, J.I.1    Schvarzstein, M.2    Villeneuve, A.M.3    Gu, S.G.4    Jantsch, V.5
  • 27
    • 71549147194 scopus 로고    scopus 로고
    • Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans
    • Pavelec DM, Lachowiec J, Duchaine TF, Smith HE, Kennedy S, (2009) Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans. Genetics 183: 1283-1295.
    • (2009) Genetics , vol.183 , pp. 1283-1295
    • Pavelec, D.M.1    Lachowiec, J.2    Duchaine, T.F.3    Smith, H.E.4    Kennedy, S.5
  • 28
    • 33845436047 scopus 로고    scopus 로고
    • Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    • Ruby JG, Jan C, Player C, Axtell MJ, Lee W, et al. (2006) Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell 127: 1193-1207.
    • (2006) Cell , vol.127 , pp. 1193-1207
    • Ruby, J.G.1    Jan, C.2    Player, C.3    Axtell, M.J.4    Lee, W.5
  • 29
    • 46149114866 scopus 로고    scopus 로고
    • PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans
    • Batista PJ, Ruby JG, Claycomb JM, Chiang R, Fahlgren N, et al. (2008) PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Mol Cell 31: 67-78.
    • (2008) Mol Cell , vol.31 , pp. 67-78
    • Batista, P.J.1    Ruby, J.G.2    Claycomb, J.M.3    Chiang, R.4    Fahlgren, N.5
  • 30
    • 46149092009 scopus 로고    scopus 로고
    • Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline
    • Das PP, Bagijn MP, Goldstein LD, Woolford JR, Lehrbach NJ, et al. (2008) Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline. Mol Cell 31: 79-90.
    • (2008) Mol Cell , vol.31 , pp. 79-90
    • Das, P.P.1    Bagijn, M.P.2    Goldstein, L.D.3    Woolford, J.R.4    Lehrbach, N.J.5
  • 31
    • 45449118682 scopus 로고    scopus 로고
    • A C. elegans Piwi, PRG-1, regulates 21U-RNAs during spermatogenesis
    • Wang G, Reinke V, (2008) A C. elegans Piwi, PRG-1, regulates 21U-RNAs during spermatogenesis. Curr Biol 18: 861-867.
    • (2008) Curr Biol , vol.18 , pp. 861-867
    • Wang, G.1    Reinke, V.2
  • 33
    • 77649253620 scopus 로고    scopus 로고
    • Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma
    • Gent JI, Lamm AT, Pavelec DM, Maniar JM, Parameswaran P, et al. (2010) Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma. Mol Cell 37: 679-689.
    • (2010) Mol Cell , vol.37 , pp. 679-689
    • Gent, J.I.1    Lamm, A.T.2    Pavelec, D.M.3    Maniar, J.M.4    Parameswaran, P.5
  • 34
    • 33750824034 scopus 로고    scopus 로고
    • Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi
    • Yigit E, Batista PJ, Bei Y, Pang KM, Chen CC, et al. (2006) Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell 127: 747-757.
    • (2006) Cell , vol.127 , pp. 747-757
    • Yigit, E.1    Batista, P.J.2    Bei, Y.3    Pang, K.M.4    Chen, C.C.5
  • 35
    • 48249091655 scopus 로고    scopus 로고
    • An Argonaute transports siRNAs from the cytoplasm to the nucleus
    • Guang S, Bochner AF, Pavelec DM, Burkhart KB, Harding S, et al. (2008) An Argonaute transports siRNAs from the cytoplasm to the nucleus. Science 321: 537-541.
    • (2008) Science , vol.321 , pp. 537-541
    • Guang, S.1    Bochner, A.F.2    Pavelec, D.M.3    Burkhart, K.B.4    Harding, S.5
  • 36
    • 70349459257 scopus 로고    scopus 로고
    • The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation
    • Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, et al. (2009) The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 139: 123-134.
    • (2009) Cell , vol.139 , pp. 123-134
    • Claycomb, J.M.1    Batista, P.J.2    Pang, K.M.3    Gu, W.4    Vasale, J.J.5
  • 37
    • 0032717319 scopus 로고    scopus 로고
    • The rde-1 gene, RNA interference, and transposon silencing in C. elegans
    • Tabara H, Sarkissian M, Kelly WG, Fleenor J, Grishok A, et al. (1999) The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99: 123-132.
    • (1999) Cell , vol.99 , pp. 123-132
    • Tabara, H.1    Sarkissian, M.2    Kelly, W.G.3    Fleenor, J.4    Grishok, A.5
  • 38
    • 33845755755 scopus 로고    scopus 로고
    • Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis
    • Tkaczuk KL, Obarska A, Bujnicki JM, (2006) Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis. BMC Evol Biol 6: 6.
    • (2006) BMC Evol Biol , vol.6 , pp. 6
    • Tkaczuk, K.L.1    Obarska, A.2    Bujnicki, J.M.3
  • 39
    • 34248229742 scopus 로고    scopus 로고
    • Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene
    • Cuppen E, Gort E, Hazendonk E, Mudde J, van de Belt J, et al. (2007) Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene. Genome research 17: 649-658.
    • (2007) Genome Research , vol.17 , pp. 649-658
    • Cuppen, E.1    Gort, E.2    Hazendonk, E.3    Mudde, J.4    van de Belt, J.5
  • 40
    • 70349939426 scopus 로고    scopus 로고
    • Structural insights into mechanisms of the small RNA methyltransferase HEN1
    • Huang Y, Ji L, Huang Q, Vassylyev DG, Chen X, et al. (2009) Structural insights into mechanisms of the small RNA methyltransferase HEN1. Nature 461: 823-827.
    • (2009) Nature , vol.461 , pp. 823-827
    • Huang, Y.1    Ji, L.2    Huang, Q.3    Vassylyev, D.G.4    Chen, X.5
  • 41
    • 33746502166 scopus 로고    scopus 로고
    • A distinct small RNA pathway silences selfish genetic elements in the germline
    • Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, et al. (2006) A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313: 320-324.
    • (2006) Science , vol.313 , pp. 320-324
    • Vagin, V.V.1    Sigova, A.2    Li, C.3    Seitz, H.4    Gvozdev, V.5
  • 42
    • 31044452870 scopus 로고    scopus 로고
    • Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways
    • Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D Jr, et al. (2006) Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell 124: 343-354.
    • (2006) Cell , vol.124 , pp. 343-354
    • Duchaine, T.F.1    Wohlschlegel, J.A.2    Kennedy, S.3    Bei, Y.4    Conte Jr., D.5
  • 43
    • 0037031152 scopus 로고    scopus 로고
    • Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi
    • Simmer F, Tijsterman M, Parrish S, Koushika SP, Nonet ML, et al. (2002) Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Current biology: CB 12: 1317-1319.
    • (2002) Current Biology: CB , vol.12 , pp. 1317-1319
    • Simmer, F.1    Tijsterman, M.2    Parrish, S.3    Koushika, S.P.4    Nonet, M.L.5
  • 44
    • 33645464445 scopus 로고    scopus 로고
    • Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans
    • Lee RC, Hammell CM, Ambros V, (2006) Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans. RNA 12: 589-597.
    • (2006) RNA , vol.12 , pp. 589-597
    • Lee, R.C.1    Hammell, C.M.2    Ambros, V.3
  • 45
    • 1342346710 scopus 로고    scopus 로고
    • A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
    • Kennedy S, Wang D, Ruvkun G, (2004) A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature 427: 645-649.
    • (2004) Nature , vol.427 , pp. 645-649
    • Kennedy, S.1    Wang, D.2    Ruvkun, G.3
  • 46
    • 77749286136 scopus 로고    scopus 로고
    • P granule assembly and function in Caenorhabditis elegans germ cells
    • Updike D, Strome S, (2010) P granule assembly and function in Caenorhabditis elegans germ cells. J Androl 31: 53-60.
    • (2010) J Androl , vol.31 , pp. 53-60
    • Updike, D.1    Strome, S.2
  • 47
    • 0035860551 scopus 로고    scopus 로고
    • A gene expression map for Caenorhabditis elegans
    • Kim SK, Lund J, Kiraly M, Duke K, Jiang M, et al. (2001) A gene expression map for Caenorhabditis elegans. Science 293: 2087-2092.
    • (2001) Science , vol.293 , pp. 2087-2092
    • Kim, S.K.1    Lund, J.2    Kiraly, M.3    Duke, K.4    Jiang, M.5
  • 49
    • 0032739015 scopus 로고    scopus 로고
    • Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
    • Ketting RF, Haverkamp TH, van Luenen HG, Plasterk RH, (1999) Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99: 133-141.
    • (1999) Cell , vol.99 , pp. 133-141
    • Ketting, R.F.1    Haverkamp, T.H.2    van Luenen, H.G.3    Plasterk, R.H.4
  • 50
    • 78650468331 scopus 로고    scopus 로고
    • Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins
    • Ameres SL, Hung JH, Xu J, Weng Z, Zamore PD, (2011) Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins. RNA 17: 54-63.
    • (2011) RNA , vol.17 , pp. 54-63
    • Ameres, S.L.1    Hung, J.H.2    Xu, J.3    Weng, Z.4    Zamore, P.D.5
  • 51
    • 84860599349 scopus 로고    scopus 로고
    • The Caenorhabditis elegans HEN1 Ortholog, HENN-1, Methylates and Stabilizes Select Subclasses of Germline Small RNAs
    • doi:10.1371/journal.pgen.1002617
    • Billi AC, Alessi AF, Khivansara V, Han T, Freeberg M, et al. (2012) The Caenorhabditis elegans HEN1 Ortholog, HENN-1, Methylates and Stabilizes Select Subclasses of Germline Small RNAs. PLoS Genet 8 (4): e1002617 doi:10.1371/journal.pgen.1002617.
    • (2012) PLoS Genet , vol.8 , Issue.4
    • Billi, A.C.1    Alessi, A.F.2    Khivansara, V.3    Han, T.4    Freeberg, M.5
  • 52
    • 84860562145 scopus 로고    scopus 로고
    • PIWI Associated siRNAs and piRNAs Specifically Require the Caenorhabditis elegans HEN1 Ortholog henn-1
    • doi:10.1371/journal.pgen.1002616
    • Montgomery TA, Rim Y-S, Zhang C, Dowen RH, Phillips CM, et al. (2012) PIWI Associated siRNAs and piRNAs Specifically Require the Caenorhabditis elegans HEN1 Ortholog henn-1. PLoS Genet 8 (4): e1002616 doi:10.1371/journal.pgen.1002616.
    • (2012) PLoS Genet , vol.8 , Issue.4
    • Montgomery, T.A.1    Rim, Y.-S.2    Zhang, C.3    Dowen, R.H.4    Phillips, C.M.5
  • 54
    • 53249143880 scopus 로고    scopus 로고
    • 3′ UTRs are the primary regulators of gene expression in the C. elegans germline
    • Merritt C, Rasoloson D, Ko D, Seydoux G, (2008) 3′ UTRs are the primary regulators of gene expression in the C. elegans germline. Curr Biol 18: 1476-1482.
    • (2008) Curr Biol , vol.18 , pp. 1476-1482
    • Merritt, C.1    Rasoloson, D.2    Ko, D.3    Seydoux, G.4
  • 55
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1    Fraser, A.G.2    Dong, Y.3    Poulin, G.4    Durbin, R.5
  • 58
    • 0000443202 scopus 로고
    • Genetic and Phenotypic Characterization of Roller Mutants of CAENORHABDITIS ELEGANS
    • Cox GN, Laufer JS, Kusch M, Edgar RS, (1980) Genetic and Phenotypic Characterization of Roller Mutants of CAENORHABDITIS ELEGANS. Genetics 95: 317-339.
    • (1980) Genetics , vol.95 , pp. 317-339
    • Cox, G.N.1    Laufer, J.S.2    Kusch, M.3    Edgar, R.S.4
  • 59
    • 0022509078 scopus 로고
    • Genetic studies of unusual loci that affect body shape of the nematode Caenorhabditis elegans and may code for cuticle structural proteins
    • Kusch M, Edgar RS, (1986) Genetic studies of unusual loci that affect body shape of the nematode Caenorhabditis elegans and may code for cuticle structural proteins. Genetics 113: 621-639.
    • (1986) Genetics , vol.113 , pp. 621-639
    • Kusch, M.1    Edgar, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.