-
1
-
-
33947656333
-
Nodal signaling: Developmental roles and regulation
-
PMID: 17287255
-
Shen MM (2007) Nodal signaling: developmental roles and regulation. Development 134: 1023-1034. doi: 10.1242/dev.000166 PMID: 17287255
-
(2007)
Development
, vol.134
, pp. 1023-1034
-
-
Shen, M.M.1
-
2
-
-
0027510084
-
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation
-
PMID: 8429908
-
Zhou X, Sasaki H, Lowe L, Hogan BL, Kuehn MR (1993) Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature 361: 543-547. doi: 10.1038/361543a0 PMID: 8429908
-
(1993)
Nature
, vol.361
, pp. 543-547
-
-
Zhou, X.1
Sasaki, H.2
Lowe, L.3
Hogan, B.L.4
Kuehn, M.R.5
-
3
-
-
0030932236
-
Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation
-
PMID: 9056778
-
Varlet I, Collignon J, Robertson EJ (1997) Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development 124: 1033-1044. PMID: 9056778
-
(1997)
Development
, vol.124
, pp. 1033-1044
-
-
Varlet, I.1
Collignon, J.2
Robertson, E.J.3
-
4
-
-
41949142373
-
Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells
-
PMID: 18334633
-
Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, et al. (2008) Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells. Proceedings of the National Academy of Sciences of the United States of America 105: 4329-4334. doi: 10.1073/pnas.0800467105 PMID: 18334633
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 4329-4334
-
-
Postovit, L.M.1
Margaryan, N.V.2
Seftor, E.A.3
Kirschmann, D.A.4
Lipavsky, A.5
-
5
-
-
0036210652
-
Cripto-1 activates nodaland ALK4-dependent and -independent signaling pathways in mammary epithelial Cells
-
PMID: 11909953
-
Bianco C, Adkins HB, Wechselberger C, Seno M, Normanno N, et al. (2002) Cripto-1 activates nodaland ALK4-dependent and -independent signaling pathways in mammary epithelial Cells. Molecular and cellular biology 22: 2586-2597. doi: 10.1128/MCB.22.8.2586-2597.2002 PMID: 11909953
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 2586-2597
-
-
Bianco, C.1
Adkins, H.B.2
Wechselberger, C.3
Seno, M.4
Normanno, N.5
-
6
-
-
71149083121
-
Expression of nodal signalling components in cycling human endometrium and in endometrial cancer
-
PMID: 25245493
-
Papageorgiou I, Nicholls PK, Wang F, Lackmann M, Makanji Y, et al. (2009) Expression of nodal signalling components in cycling human endometrium and in endometrial cancer. Reproductive biology and endocrinology: RB&E 7: 122. doi: 10.1186/1477-7827-12-91 PMID: 25245493
-
(2009)
Reproductive Biology and Endocrinology: RB&E
, vol.7
, pp. 122
-
-
Papageorgiou, I.1
Nicholls, P.K.2
Wang, F.3
Lackmann, M.4
Makanji, Y.5
-
7
-
-
33751516578
-
Isolation and characterization of a stem cell population from adult human liver
-
PMID: 16945998
-
Herrera MB, Bruno S, Buttiglieri S, Tetta C, Gatti S, et al. (2006) Isolation and characterization of a stem cell population from adult human liver. Stem Cells 24: 2840-2850. doi: 10.1634/stemcells.2006-0114 PMID: 16945998
-
(2006)
Stem Cells
, vol.24
, pp. 2840-2850
-
-
Herrera, M.B.1
Bruno, S.2
Buttiglieri, S.3
Tetta, C.4
Gatti, S.5
-
8
-
-
33746846469
-
Embryonic and tumorigenic pathways converge via Nodal signaling: Role in melanoma aggressiveness
-
PMID: 16892036
-
Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, et al. (2006) Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nature medicine 12: 925-932. doi: 10.1038/nm1448 PMID: 16892036
-
(2006)
Nature Medicine
, vol.12
, pp. 925-932
-
-
Topczewska, J.M.1
Postovit, L.M.2
Margaryan, N.V.3
Sam, A.4
Hess, A.R.5
-
9
-
-
80755141299
-
Nodal/Activin signaling drives selfrenewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy
-
PMID: 22056140
-
Lonardo E, Hermann PC, Mueller MT, Huber S, Balic A, et al. (2011) Nodal/Activin signaling drives selfrenewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy. Cell stem cell 9: 433-446. doi: 10.1016/j.stem.2011.10.001 PMID: 22056140
-
(2011)
Cell Stem Cell
, vol.9
, pp. 433-446
-
-
Lonardo, E.1
Hermann, P.C.2
Mueller, M.T.3
Huber, S.4
Balic, A.5
-
10
-
-
84868688889
-
Embryonic morphogen nodal promotes breast cancer growth and progression
-
PMID: 23144858
-
Quail DF, Zhang G, Walsh LA, Siegers GM, Dieters-Castator DZ, et al. (2012) Embryonic morphogen nodal promotes breast cancer growth and progression. PloS one 7: e48237. doi: 10.1371/journal. pone.0048237 PMID: 23144858
-
(2012)
PloS One
, vol.7
-
-
Quail, D.F.1
Zhang, G.2
Walsh, L.A.3
Siegers, G.M.4
Dieters-Castator, D.Z.5
-
11
-
-
84860804090
-
Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer
-
PMID: 22577960
-
Strizzi L, Hardy KM, Margaryan NV, Hillman DW, Seftor EA, et al. (2012) Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer. Breast Cancer Res 14: R75. doi: 10.1186/bcr3185 PMID: 22577960
-
(2012)
Breast Cancer Res
, vol.14
, pp. R75
-
-
Strizzi, L.1
Hardy, K.M.2
Margaryan, N.V.3
Hillman, D.W.4
Seftor, E.A.5
-
12
-
-
57049152264
-
Emerging roles of nodal and Cripto-1: From embryogenesis to breast cancer progression
-
PMID: 19029628
-
Strizzi L, Postovit LM, Margaryan NV, Seftor EA, Abbott DE, et al. (2008) Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression. Breast disease 29: 91-103. PMID: 19029628
-
(2008)
Breast Disease
, vol.29
, pp. 91-103
-
-
Strizzi, L.1
Postovit, L.M.2
Margaryan, N.V.3
Seftor, E.A.4
Abbott, D.E.5
-
13
-
-
84897032310
-
Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway
-
PMID: 23334323
-
Quail DF, Zhang G, Findlay SD, Hess DA, Postovit LM (2013) Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway. Oncogene. PMID: 23334323
-
(2013)
Oncogene
-
-
Quail, D.F.1
Zhang, G.2
Findlay, S.D.3
Hess, D.A.4
Postovit, L.M.5
-
14
-
-
84876072941
-
Nodal promotes aggressive phenotype via Snail-mediated epithelial-mesenchymal transition in murine melanoma
-
Fang R, Zhang G, Guo Q, Ning F, Wang H, et al. (2013) Nodal promotes aggressive phenotype via Snail-mediated epithelial-mesenchymal transition in murine melanoma. Cancer Lett. doi: 10.1016/j. canlet.2013.01.014
-
(2013)
Cancer Lett
-
-
Fang, R.1
Zhang, G.2
Guo, Q.3
Ning, F.4
Wang, H.5
-
15
-
-
40049099699
-
Oral administration of GW788388, an inhibitor of TGF-beta type i and II receptor kinases, decreases renal fibrosis
-
PMID: 18075500
-
Petersen M, Thorikay M, Deckers M, van Dinther M, Grygielko ET, et al. (2008) Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis. Kidney International 73: 705-715. doi: 10.1038/sj.ki.5002717 PMID: 18075500
-
(2008)
Kidney International
, vol.73
, pp. 705-715
-
-
Petersen, M.1
Thorikay, M.2
Deckers, M.3
Van Dinther, M.4
Grygielko, E.T.5
-
16
-
-
0036085920
-
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type i activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
-
PMID: 12065756
-
Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, et al. (2002) SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 62: 65-74. doi: 10.1124/mol.62.1.65 PMID: 12065756
-
(2002)
Mol Pharmacol
, vol.62
, pp. 65-74
-
-
Inman, G.J.1
Nicolas, F.J.2
Callahan, J.F.3
Harling, J.D.4
Gaster, L.M.5
-
17
-
-
1842762249
-
Two modes by which Lefty proteins inhibit nodal signaling
-
PMID: 15062104
-
Chen C, Shen MM (2004) Two modes by which Lefty proteins inhibit nodal signaling. Current biology: CB 14: 618-624. doi: 10.1016/j.cub.2004.02.042 PMID: 15062104
-
(2004)
Current Biology: CB
, vol.14
, pp. 618-624
-
-
Chen, C.1
Shen, M.M.2
-
18
-
-
0033602241
-
The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals
-
PMID: 10067895
-
Piccolo S, Agius E, Leyns L, Bhattacharyya S, Grunz H, et al. (1999) The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature 397: 707-710. doi: 10.1038/17820 PMID: 10067895
-
(1999)
Nature
, vol.397
, pp. 707-710
-
-
Piccolo, S.1
Agius, E.2
Leyns, L.3
Bhattacharyya, S.4
Grunz, H.5
-
19
-
-
0033197552
-
Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation
-
PMID: 10518210
-
Meno C, Gritsman K, Ohishi S, Ohfuji Y, Heckscher E, et al. (1999) Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Molecular cell 4: 287-298. doi: 10.1016/S1097-2765(00)80331-7 PMID: 10518210
-
(1999)
Molecular Cell
, vol.4
, pp. 287-298
-
-
Meno, C.1
Gritsman, K.2
Ohishi, S.3
Ohfuji, Y.4
Heckscher, E.5
-
20
-
-
0036240683
-
Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion
-
Sakuma R, Ohnishi Yi Y, Meno C, Fujii H, Juan H, et al. (2002) Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion. Genes to cells: devoted to molecular & cellular mechanisms 7: 401-412. doi: 10.1046/j.1365-2443.2002.00528.x
-
(2002)
Genes to Cells: Devoted to Molecular & Cellular Mechanisms
, vol.7
, pp. 401-412
-
-
Sakuma, R.1
Ohnishi Yi, Y.2
Meno, C.3
Fujii, H.4
Juan, H.5
-
21
-
-
4644289915
-
The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis
-
PMID: 15466485
-
Marques S, Borges AC, Silva AC, Freitas S, Cordenonsi M, et al. (2004) The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev 18: 2342-2347. doi: 10.1101/gad.306504 PMID: 15466485
-
(2004)
Genes Dev
, vol.18
, pp. 2342-2347
-
-
Marques, S.1
Borges, A.C.2
Silva, A.C.3
Freitas, S.4
Cordenonsi, M.5
-
22
-
-
0036850429
-
The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling
-
PMID: 12431379
-
Bertocchini F, Stern CD (2002) The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling. Dev Cell 3: 735-744. doi: 10.1016/S1534-5807(02)00318-0 PMID: 12431379
-
(2002)
Dev Cell
, vol.3
, pp. 735-744
-
-
Bertocchini, F.1
Stern, C.D.2
-
23
-
-
0034078755
-
Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development
-
PMID: 10748465
-
Belo JA, Bachiller D, Agius E, Kemp C, Borges AC, et al. (2000) Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development. Genesis 26: 265-270. doi: 10.1002/(SICI) 1526-968X(200004)26:4%3C265::AID-GENE80%3E3.3.CO;2-W PMID: 10748465
-
(2000)
Genesis
, vol.26
, pp. 265-270
-
-
Belo, J.A.1
Bachiller, D.2
Agius, E.3
Kemp, C.4
Borges, A.C.5
-
24
-
-
33947583623
-
Reprogramming metastatic tumour cells with embryonic microenvironments
-
PMID: 17384580
-
Hendrix MJ, Seftor EA, Seftor RE, Kasemeier-Kulesa J, Kulesa PM, et al. (2007) Reprogramming metastatic tumour cells with embryonic microenvironments. Nature reviews Cancer 7: 246-255. doi: 10. 1038/nrc2108 PMID: 17384580
-
(2007)
Nature Reviews Cancer
, vol.7
, pp. 246-255
-
-
Hendrix, M.J.1
Seftor, E.A.2
Seftor, R.E.3
Kasemeier-Kulesa, J.4
Kulesa, P.M.5
-
25
-
-
0031685620
-
TGF-beta signal transduction
-
PMID: 9759503
-
Massague J (1998) TGF-beta signal transduction. Annu Rev Biochem 67: 753-791. doi: 10.1146/ annurev.biochem.67.1.753 PMID: 9759503
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
26
-
-
0035947301
-
Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms
-
PMID: 11389842
-
Yeo C, Whitman M (2001) Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms. Molecular cell 7: 949-957. doi: 10.1016/S1097-2765(01)00249-0 PMID: 11389842
-
(2001)
Molecular Cell
, vol.7
, pp. 949-957
-
-
Yeo, C.1
Whitman, M.2
-
27
-
-
0035425463
-
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
-
Reissmann E, Jornvall H, Blokzijl A, Andersson O, Chang C, et al. (2001) The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes & development 15: 2010-2022. doi: 10.1101/gad.201801
-
(2001)
Genes & Development
, vol.15
, pp. 2010-2022
-
-
Reissmann, E.1
Jornvall, H.2
Blokzijl, A.3
Andersson, O.4
Chang, C.5
-
28
-
-
67650096520
-
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression
-
PMID: 19279133
-
Vallier L, Mendjan S, Brown S, Chng Z, Teo A, et al. (2009) Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. Development 136: 1339-1349. doi: 10.1242/dev.033951 PMID: 19279133
-
(2009)
Development
, vol.136
, pp. 1339-1349
-
-
Vallier, L.1
Mendjan, S.2
Brown, S.3
Chng, Z.4
Teo, A.5
-
29
-
-
67549101912
-
Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus
-
PMID: 19389392
-
Zhang C, KlymkowskyMW(2009) Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. Dev Biol 331: 340-349. doi: 10. 1016/j.ydbio.2009.04.016 PMID: 19389392
-
(2009)
Dev Biol
, vol.331
, pp. 340-349
-
-
Zhang, C.1
Klymkowsky, M.W.2
-
30
-
-
79960888524
-
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors
-
PMID: 21630377
-
Brown S, Teo A, Pauklin S, Hannan N, Cho CH, et al. (2011) Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors. Stem Cells 29: 1176-1185. doi: 10.1002/stem.666 PMID: 21630377
-
(2011)
Stem Cells
, vol.29
, pp. 1176-1185
-
-
Brown, S.1
Teo, A.2
Pauklin, S.3
Hannan, N.4
Cho, C.H.5
-
31
-
-
0035808459
-
Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads
-
PMID: 11024047
-
Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, et al. (2001) Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads. The Journal of biological chemistry 276: 656-661. doi: 10.1074/jbc.M004649200 PMID: 11024047
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 656-661
-
-
Kumar, A.1
Novoselov, V.2
Celeste, A.J.3
Wolfman, N.M.4
Ten Dijke, P.5
-
32
-
-
0036275653
-
Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
-
PMID: 12052855
-
Yan YT, Liu JJ, Luo Y, E C, Haltiwanger RS, et al. (2002) Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway. Molecular and cellular biology 22: 4439-4449. doi: 10.1128/MCB.22. 13.4439-4449.2002 PMID: 12052855
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 4439-4449
-
-
Yan, Y.T.1
Liu, J.J.2
Luo, Y.3
Haltiwanger, R.S.4
-
33
-
-
0033515638
-
The EGF-CFC protein one-eyed pinhead is essential for nodal signaling
-
PMID: 10199408
-
Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, et al. (1999) The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell 97: 121-132. doi: 10.1016/S0092-8674(00)80720-5 PMID: 10199408
-
(1999)
Cell
, vol.97
, pp. 121-132
-
-
Gritsman, K.1
Zhang, J.2
Cheng, S.3
Heckscher, E.4
Talbot, W.S.5
-
34
-
-
84881540151
-
The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration
-
PMID: 23967175
-
Wu X, Gallo KA (2013) The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration. PLoS One 8: e71258. doi: 10.1371/journal.pone. 0071258 PMID: 23967175
-
(2013)
PLoS One
, vol.8
-
-
Wu, X.1
Gallo, K.A.2
-
35
-
-
84921891146
-
MicroRNA-200b targets protein kinase Calpha and suppresses triple-negative breast cancer metastasis
-
PMID: 24925028
-
Humphries B, Wang Z, Oom AL, Fisher T, Tan D, et al. (2014) MicroRNA-200b targets protein kinase Calpha and suppresses triple-negative breast cancer metastasis. Carcinogenesis. doi: 10.1093/carcin/ bgu133 PMID: 24925028
-
(2014)
Carcinogenesis
-
-
Humphries, B.1
Wang, Z.2
Oom, A.L.3
Fisher, T.4
Tan, D.5
-
36
-
-
77954235817
-
Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb
-
PMID: 20385559
-
Sako D, Grinberg AV, Liu J, Davies MV, Castonguay R, et al. (2010) Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb. The Journal of biological chemistry 285: 21037-21048. doi: 10.1074/jbc.M110.114959 PMID: 20385559
-
(2010)
The Journal of Biological Chemistry
, vol.285
, pp. 21037-21048
-
-
Sako, D.1
Grinberg, A.V.2
Liu, J.3
Davies, M.V.4
Castonguay, R.5
-
37
-
-
84864990335
-
Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex
-
PMID: 22718755
-
Townson SA, Martinez-Hackert E, Greppi C, Lowden P, Sako D, et al. (2012) Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex. The Journal of biological chemistry 287: 27313-27325. doi: 10.1074/jbc.M112.377960 PMID: 22718755
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 27313-27325
-
-
Townson, S.A.1
Martinez-Hackert, E.2
Greppi, C.3
Lowden, P.4
Sako, D.5
-
38
-
-
0242684423
-
Transforming growth factorbeta (TGF-beta) binding to the extracellular domain of the type II TGF-beta receptor: Receptor capture on a biosensor surface using a new coiled-coil capture system demonstrates that avidity contributes significantly to high affinity binding
-
PMID: 12729750
-
De Crescenzo G, Pham PL, Durocher Y, O'Connor-McCourt MD (2003) Transforming growth factorbeta (TGF-beta) binding to the extracellular domain of the type II TGF-beta receptor: receptor capture on a biosensor surface using a new coiled-coil capture system demonstrates that avidity contributes significantly to high affinity binding. J Mol Biol 328: 1173-1183. PMID: 12729750
-
(2003)
J Mol Biol
, vol.328
, pp. 1173-1183
-
-
De Crescenzo, G.1
Pham, P.L.2
Durocher, Y.3
O'Connor-Mccourt, M.D.4
-
40
-
-
57149120532
-
Cerberus functions as a BMP agonist to synergistically induce nodal expression during left-right axis determination in the chick embryo
-
PMID: 18985739
-
Yu X, He F, Zhang T, Espinoza-Lewis RA, Lin L, et al. (2008) Cerberus functions as a BMP agonist to synergistically induce nodal expression during left-right axis determination in the chick embryo. Dev Dyn 237: 3613-3623. doi: 10.1002/dvdy.21769 PMID: 18985739
-
(2008)
Dev Dyn
, vol.237
, pp. 3613-3623
-
-
Yu, X.1
He, F.2
Zhang, T.3
Espinoza-Lewis, R.A.4
Lin, L.5
-
41
-
-
0032039482
-
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
-
Hsu DR, Economides AN, Wang X, Eimon PM, Harland RM (1998) The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell 1: 673-683. doi: 10.1016/S1097-2765(00)80067-2 PMID: 9660951
-
(1998)
Mol Cell
, vol.1
, pp. 673-683
-
-
Hsu, D.R.1
Economides, A.N.2
Wang, X.3
Eimon, P.M.4
Harland, R.M.5
-
42
-
-
81255128937
-
A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development
-
PMID: 22114682
-
Chi L, Saarela U, Railo A, Prunskaite-Hyyrylainen R, Skovorodkin I, et al. (2011) A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development. PLoS One 6: e27676. doi: 10.1371/journal.pone.0027676 PMID: 22114682
-
(2011)
PLoS One
, vol.6
-
-
Chi, L.1
Saarela, U.2
Railo, A.3
Prunskaite-Hyyrylainen, R.4
Skovorodkin, I.5
-
43
-
-
84887039950
-
Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment
-
PMID: 24186978
-
Cai W, Albini S, Wei K, Willems E, Guzzo RM, et al. (2013) Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment. Genes Dev 27: 2332-2344. doi: 10.1101/gad.225144. 113 PMID: 24186978
-
(2013)
Genes Dev
, vol.27
, pp. 2332-2344
-
-
Cai, W.1
Albini, S.2
Wei, K.3
Willems, E.4
Guzzo, R.M.5
-
44
-
-
33846969204
-
Multiple functions of Cerberus cooperate to induce heart downstream of Nodal
-
PMID: 17123501
-
Foley AC, Korol O, Timmer AM, Mercola M (2007) Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. Developmental biology 303: 57-65. doi: 10.1016/j.ydbio.2006.10.033 PMID: 17123501
-
(2007)
Developmental Biology
, vol.303
, pp. 57-65
-
-
Foley, A.C.1
Korol, O.2
Timmer, A.M.3
Mercola, M.4
-
45
-
-
0032014216
-
Human Smad3 and Smad4 are sequence- specific transcription activators
-
PMID: 9660945
-
Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, et al. (1998) Human Smad3 and Smad4 are sequence- specific transcription activators. Mol Cell 1: 611-617. doi: 10.1016/S1097-2765(00)80061-1 PMID: 9660945
-
(1998)
Mol Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Dai, J.L.2
Buckhaults, P.3
Zhou, S.4
Kinzler, K.W.5
-
46
-
-
84864830700
-
Embryonic protein nodal promotes breast cancer vascularization
-
PMID: 22855743
-
Quail DF, Walsh LA, Zhang G, Findlay SD, Moreno J, et al. (2012) Embryonic protein nodal promotes breast cancer vascularization. Cancer research 72: 3851-3863. doi: 10.1158/0008-5472.CAN-11- 3951 PMID: 22855743
-
(2012)
Cancer Research
, vol.72
, pp. 3851-3863
-
-
Quail, D.F.1
Walsh, L.A.2
Zhang, G.3
Findlay, S.D.4
Moreno, J.5
-
47
-
-
84860133351
-
Nodal expression and detection in cancer: Experience and challenges
-
PMID: 22508696
-
Strizzi L, Hardy KM, Kirschmann DA, Ahrlund-Richter L, Hendrix MJ (2012) Nodal expression and detection in cancer: experience and challenges. Cancer research 72: 1915-1920. doi: 10.1158/0008- 5472.CAN-11-3419 PMID: 22508696
-
(2012)
Cancer Research
, vol.72
, pp. 1915-1920
-
-
Strizzi, L.1
Hardy, K.M.2
Kirschmann, D.A.3
Ahrlund-Richter, L.4
Hendrix, M.J.5
-
48
-
-
33751346643
-
CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: An early step necessary for metastasis
-
PMID: 17062128
-
Sheridan C, Kishimoto H, Fuchs RK, Mehrotra S, Bhat-Nakshatri P, et al. (2006) CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res 8: R59. doi: 10.1186/bcr1610 PMID: 17062128
-
(2006)
Breast Cancer Res
, vol.8
, pp. R59
-
-
Sheridan, C.1
Kishimoto, H.2
Fuchs, R.K.3
Mehrotra, S.4
Bhat-Nakshatri, P.5
-
49
-
-
0028138771
-
Differentiation state and invasiveness of human breast cancer cell lines
-
PMID: 7881109
-
Sommers CL, Byers SW, Thompson EW, Torri JA, Gelmann EP (1994) Differentiation state and invasiveness of human breast cancer cell lines. Breast Cancer Res Treat 31: 325-335. doi: 10.1007/ BF00666165 PMID: 7881109
-
(1994)
Breast Cancer Res Treat
, vol.31
, pp. 325-335
-
-
Sommers, C.L.1
Byers, S.W.2
Thompson, E.W.3
Torri, J.A.4
Gelmann, E.P.5
-
50
-
-
0345255908
-
Nodal signaling in vertebrate development
-
PMID: 14570583
-
Schier AF (2003) Nodal signaling in vertebrate development. Annual review of cell and developmental biology 19: 589-621. doi: 10.1146/annurev.cellbio.19.041603.094522 PMID: 14570583
-
(2003)
Annual Review of Cell and Developmental Biology
, vol.19
, pp. 589-621
-
-
Schier, A.F.1
-
51
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
PMID: 12809600
-
Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700. doi: 10.1016/S0092-8674(03)00432-X PMID: 12809600
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
52
-
-
63449092615
-
Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor
-
Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, et al. (2009) Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor. Journal of peptide science: an official publication of the European Peptide Society 15: 175-183. doi: 10.1002/psc.1091
-
(2009)
Journal of Peptide Science: An Official Publication of the European Peptide Society
, vol.15
, pp. 175-183
-
-
Calvanese, L.1
Saporito, A.2
Oliva, R.3
D'Auria, G.4
Pedone, C.5
-
53
-
-
41949137589
-
Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal
-
PMID: 18089557
-
Kelber JA, Shani G, Booker EC, Vale WW, Gray PC (2008) Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal. The Journal of biological chemistry 283: 4490-4500. doi: 10.1074/jbc.M704960200 PMID: 18089557
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 4490-4500
-
-
Kelber, J.A.1
Shani, G.2
Booker, E.C.3
Vale, W.W.4
Gray, P.C.5
-
54
-
-
85047693731
-
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo
-
PMID: 12925698
-
Adkins HB, Bianco C, Schiffer SG, Rayhorn P, Zafari M, et al. (2003) Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo. The Journal of clinical investigation 112: 575-587. doi: 10.1172/JCI17788 PMID: 12925698
-
(2003)
The Journal of Clinical Investigation
, vol.112
, pp. 575-587
-
-
Adkins, H.B.1
Bianco, C.2
Schiffer, S.G.3
Rayhorn, P.4
Zafari, M.5
-
55
-
-
84903444925
-
Nodal.Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation
-
PMID: 24798330
-
Fuerer C, Nostro MC, Constam DB (2014) Nodal.Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation. J Biol Chem 289: 17854-17871. doi: 10.1074/jbc.M114.550301 PMID: 24798330
-
(2014)
J Biol Chem
, vol.289
, pp. 17854-17871
-
-
Fuerer, C.1
Nostro, M.C.2
Constam, D.B.3
-
56
-
-
84862752910
-
Structural studies of the TGF-betas and their receptors-insights into evolution of the TGF-beta superfamily
-
PMID: 22651914
-
Hinck AP (2012) Structural studies of the TGF-betas and their receptors-insights into evolution of the TGF-beta superfamily. FEBS Lett 586: 1860-1870. doi: 10.1016/j.febslet.2012.05.028 PMID: 22651914
-
(2012)
FEBS Lett
, vol.586
, pp. 1860-1870
-
-
Hinck, A.P.1
-
57
-
-
38649088246
-
Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding
-
PMID: 18243111
-
Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, et al. (2008) Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol Cell 29: 157-168. doi: 10.1016/j.molcel.2007.11.039 PMID: 18243111
-
(2008)
Mol Cell
, vol.29
, pp. 157-168
-
-
Groppe, J.1
Hinck, C.S.2
Samavarchi-Tehrani, P.3
Zubieta, C.4
Schuermann, J.P.5
-
58
-
-
84881428594
-
Structure of protein related to Dan and Cerberus: Insights into the mechanism of bone morphogenetic protein antagonism
-
PMID: 23850456
-
Nolan K, Kattamuri C, Luedeke DM, Deng X, Jagpal A, et al. (2013) Structure of protein related to Dan and Cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure 21: 1417-1429. doi: 10.1016/j.str.2013.06.005 PMID: 23850456
-
(2013)
Structure
, vol.21
, pp. 1417-1429
-
-
Nolan, K.1
Kattamuri, C.2
Luedeke, D.M.3
Deng, X.4
Jagpal, A.5
|