-
1
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
PMID: 22150039
-
McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med. 2011; 365: 2205-2219. doi: 10.1056/NEJMra1004965 PMID: 22150039
-
(2011)
N Engl J Med
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
2
-
-
0034040746
-
Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides
-
PMID: 10728753
-
Van Der Heijden IM, Wilbrink B, Tchetverikov I, Schrijver IA, Schouls LM, Hazenberg MP, et al. Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides. Arthritis Rheum. 2000; 43: 593-598. PMID: 10728753
-
(2000)
Arthritis Rheum
, vol.43
, pp. 593-598
-
-
Van Der Heijden, I.M.1
Wilbrink, B.2
Tchetverikov, I.3
Schrijver, I.A.4
Schouls, L.M.5
Hazenberg, M.P.6
-
3
-
-
79957774659
-
Why does chronic inflammation persist: An unexpected role for fibroblasts
-
PMID: 21333681
-
Buckley CD. Why does chronic inflammation persist: An unexpected role for fibroblasts. Immunol Lett. 2011; 138: 12-14. doi: 10.1016/j.imlet.2011.02.010 PMID: 21333681
-
(2011)
Immunol Lett
, vol.138
, pp. 12-14
-
-
Buckley, C.D.1
-
4
-
-
73249125200
-
Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis
-
PMID: 20193003
-
Bartok B, Firestein GS. Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol Rev. 2010; 233: 233-255. doi: 10.1111/j.0105-2896.2009.00859.x PMID: 20193003
-
(2010)
Immunol Rev
, vol.233
, pp. 233-255
-
-
Bartok, B.1
Firestein, G.S.2
-
5
-
-
52949153587
-
Arachidonic-acid-derived eicosanoids: Roles in biology and immunopathology
-
PMID: 18774339
-
Harizi H, Corcuff JB, Gualde N. Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology. Trends Mol Med. 2008; 14: 461-469. doi: 10.1016/j.molmed.2008.08.005 PMID: 18774339
-
(2008)
Trends Mol Med
, vol.14
, pp. 461-469
-
-
Harizi, H.1
Corcuff, J.B.2
Gualde, N.3
-
6
-
-
84855361145
-
Regulation of Immune Responses by Prostaglandin E2
-
PMID: 22187483
-
Kalinski P. Regulation of Immune Responses by Prostaglandin E2. J Immunol. 2012; 188: 21-28. doi: 10.4049/jimmunol.1101029 PMID: 22187483
-
(2012)
J Immunol
, vol.188
, pp. 21-28
-
-
Kalinski, P.1
-
7
-
-
0017482122
-
Immunohistochemical localization of prostaglandin E in rheumatoid synovial tissues
-
PMID: 324481
-
Husby G, Bankhurst AD, Williams RC. Immunohistochemical localization of prostaglandin E in rheumatoid synovial tissues. Arthritis Rheum. 1977; 20: 785-791. PMID: 324481
-
(1977)
Arthritis Rheum
, vol.20
, pp. 785-791
-
-
Husby, G.1
Bankhurst, A.D.2
Williams, R.C.3
-
8
-
-
79951873360
-
Lipid Mediators in Life Science
-
PMID: 21325748
-
Murakami M. Lipid Mediators in Life Science. Exp Anim. 2011; 60: 7-20. PMID: 21325748
-
(2011)
Exp Anim
, vol.60
, pp. 7-20
-
-
Murakami, M.1
-
9
-
-
80054082654
-
Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
-
PMID: 21910409
-
Dennis EA, Cao J, Hsu Y, Magrioti V, Kokotos G. Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention. Chem Rev. 2011; 111: 6130-6185. doi: 10.1021/cr200085w PMID: 21910409
-
(2011)
Chem Rev
, vol.111
, pp. 6130-6185
-
-
Dennis, E.A.1
Cao, J.2
Hsu, Y.3
Magrioti, V.4
Kokotos, G.5
-
10
-
-
0027963388
-
Acyl-chain selectivity of the 85 kDa phospholipase A2 and of the release process in intact macrophages
-
Sundler R, Winstedt D, Wijkander J. Acyl-chain selectivity of the 85 kDa phospholipase A2 and of the release process in intact macrophages. Biochem J. 1994; 15: 455-458.
-
(1994)
Biochem J
, vol.15
, pp. 455-458
-
-
Sundler, R.1
Winstedt, D.2
Wijkander, J.3
-
11
-
-
0037073750
-
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2
-
PMID: 12359733
-
Singer AG, Ghomashchi F, Le Calvez C, Bollinger J, Bezzine S, Rouault M, et al. Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2. J Biol Chem. 2002; 277: 48535-48549. PMID: 12359733
-
(2002)
J Biol Chem
, vol.277
, pp. 48535-48549
-
-
Singer, A.G.1
Ghomashchi, F.2
Le Calvez, C.3
Bollinger, J.4
Bezzine, S.5
Rouault, M.6
-
12
-
-
0031806559
-
Interfacial activation, lysophospholipase and transacylase activity of group VI Ca2+-independent phospholipase A2
-
PMID: 9630702
-
Lio YC, Dennis EA. Interfacial activation, lysophospholipase and transacylase activity of group VI Ca2+-independent phospholipase A2. Biochim Biophys Acta. 1998; 1392: 320-332. PMID: 9630702
-
(1998)
Biochim Biophys Acta
, vol.1392
, pp. 320-332
-
-
Lio, Y.C.1
Dennis, E.A.2
-
13
-
-
0031445523
-
Role of cytosolic phospholipase A2 in allergic response and parturition
-
PMID: 9403692
-
Uozumi N, Kume K, Nagase T, Nakatani N, Ishii S, Tashiro F, et al. Role of cytosolic phospholipase A2 in allergic response and parturition. Nature. 1997; 390: 618-622. PMID: 9403692
-
(1997)
Nature
, vol.390
, pp. 618-622
-
-
Uozumi, N.1
Kume, K.2
Nagase, T.3
Nakatani, N.4
Ishii, S.5
Tashiro, F.6
-
14
-
-
0036113192
-
A pivotal role of cytosolic phospholipase A2 in bleomycin-induced pulmonary fibrosis
-
PMID: 11984592
-
Nagase T, Uozumi N, Ishii S, Kita Y, Yamamoto H, Ohga E, et al. A pivotal role of cytosolic phospholipase A2 in bleomycin-induced pulmonary fibrosis. Nat Med. 2002; 8: 480-484. PMID: 11984592
-
(2002)
Nat Med
, vol.8
, pp. 480-484
-
-
Nagase, T.1
Uozumi, N.2
Ishii, S.3
Kita, Y.4
Yamamoto, H.5
Ohga, E.6
-
15
-
-
0034232013
-
Acute lung injury by sepsis and acid aspiration: A key role for cytosolic phospholipase A2
-
PMID: 10881173
-
Nagase T, Uozumi N, Ishii S, Kume K, Izumi T, Ouchi Y, et al. Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2. Nat Immunol. 2000; 1: 42-46. PMID: 10881173
-
(2000)
Nat Immunol
, vol.1
, pp. 42-46
-
-
Nagase, T.1
Uozumi, N.2
Ishii, S.3
Kume, K.4
Izumi, T.5
Ouchi, Y.6
-
16
-
-
0037561999
-
Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis
-
PMID: 12743172
-
Hegen M, Sun L, Uozumi N, Kume K, Goad ME, Nickerson-Nutter CL, et al. Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis. J Exp Med. 2003; 197: 1297-1302. PMID: 12743172
-
(2003)
J Exp Med
, vol.197
, pp. 1297-1302
-
-
Hegen, M.1
Sun, L.2
Uozumi, N.3
Kume, K.4
Goad, M.E.5
Nickerson-Nutter, C.L.6
-
17
-
-
33646857678
-
Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice
-
PMID: 16712837
-
Malaviya R, Ansell J, Hall L, Fahmy M, Argentieri RL, Olini JGC, et al. Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice. Eur J Pharmacol. 2006; 539: 195-204. PMID: 16712837
-
(2006)
Eur J Pharmacol
, vol.539
, pp. 195-204
-
-
Malaviya, R.1
Ansell, J.2
Hall, L.3
Fahmy, M.4
Argentieri, R.L.5
Olini, J.G.C.6
-
18
-
-
77649104362
-
Cytosolic phospholipase A2 alpha inhibitor, pyrroxyphene, displays anti-arthritic and anti-bone destructive action in a murine arthritis model
-
PMID: 19655230
-
Tai N, Kuwabara K, Kobayashi M, Yamada K, Ono T, Seno K, et al. Cytosolic phospholipase A2 alpha inhibitor, pyrroxyphene, displays anti-arthritic and anti-bone destructive action in a murine arthritis model. Inflamm Res. 2010; 59: 53-62. doi: 10.1007/s00011-009-0069-8 PMID: 19655230
-
(2010)
Inflamm Res
, vol.59
, pp. 53-62
-
-
Tai, N.1
Kuwabara, K.2
Kobayashi, M.3
Yamada, K.4
Ono, T.5
Seno, K.6
-
19
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
PMID: 20404851
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol. 2010; 11: 373-384. doi: 10.1038/ni.1863 PMID: 20404851
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
20
-
-
84855163540
-
Intrinsic danger: Activation of Toll-like receptors in rheumatoid arthritis
-
PMID: 21984766
-
Goh FG, Midwood KS. Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis. Rheumatology. 2012; 51: 7-23. doi: 10.1093/rheumatology/ker257 PMID: 21984766
-
(2012)
Rheumatology
, vol.51
, pp. 7-23
-
-
Goh, F.G.1
Midwood, K.S.2
-
21
-
-
65249190995
-
Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling
-
PMID: 19342676
-
Huang Q-Q, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AM, Tak PP, et al. Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling. J Immunol. 2009; 182: 4965-4973. doi: 10.4049/jimmunol.0801563 PMID: 19342676
-
(2009)
J Immunol
, vol.182
, pp. 4965-4973
-
-
Huang, Q.-Q.1
Sobkoviak, R.2
Jockheck-Clark, A.R.3
Shi, B.4
Mandelin, A.M.5
Tak, P.P.6
-
22
-
-
0032528185
-
Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs
-
PMID: 9664071
-
Schett G, Redlich K, Xu Q, Bizan P, Gröger M, Tohidast-Akrad M, et al. Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs. J Clin Invest. 1998; 102: 302-311. PMID: 9664071
-
(1998)
J Clin Invest
, vol.102
, pp. 302-311
-
-
Schett, G.1
Redlich, K.2
Xu, Q.3
Bizan, P.4
Gröger, M.5
Tohidast-Akrad, M.6
-
23
-
-
79955551778
-
Expression of Toll-like Receptors and Their Signaling Pathways in Rheumatoid Synovitis
-
PMID: 21324962
-
Tamaki Y, Takakubo Y, Hirayama T, Konttinen YT, Goodman SB, Yamakawa M, et al. Expression of Toll-like Receptors and Their Signaling Pathways in Rheumatoid Synovitis. J Rheumatol. 2011; 38: 810-820. doi: 10.3899/jrheum.100732 PMID: 21324962
-
(2011)
J Rheumatol
, vol.38
, pp. 810-820
-
-
Tamaki, Y.1
Takakubo, Y.2
Hirayama, T.3
Konttinen, Y.T.4
Goodman, S.B.5
Yamakawa, M.6
-
24
-
-
0037378466
-
Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium
-
PMID: 12651614
-
Seibl R, Birchler T, Loeliger S, Hossle J, Gay R, Saurenmann T, et al. Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium. Am J Pathol. 2003; 162: 1221-1227. PMID: 12651614
-
(2003)
Am J Pathol
, vol.162
, pp. 1221-1227
-
-
Seibl, R.1
Birchler, T.2
Loeliger, S.3
Hossle, J.4
Gay, R.5
Saurenmann, T.6
-
25
-
-
69449087223
-
TLR2 ligands augment cPLA2α activity and lead to enhanced leukotriene release in human monocytes
-
PMID: 19401382
-
Lindner SC, Köhl U, Maier TJ, Steinhilber D, Sorg BL. TLR2 ligands augment cPLA2α activity and lead to enhanced leukotriene release in human monocytes. J Leukoc Biol. 2009; 86: 389-399. doi: 10.1189/jlb.1008591 PMID: 19401382
-
(2009)
J Leukoc Biol
, vol.86
, pp. 389-399
-
-
Lindner, S.C.1
Köhl, U.2
Maier, T.J.3
Steinhilber, D.4
Sorg, B.L.5
-
26
-
-
65449146342
-
Coordinate Regulation of TLR-Mediated Arachidonic Acid Mobilization in Macrophages by Group IVA and Group V Phospholipase A2s
-
PMID: 19265167
-
Ruipérez V, Astudillo AM, Balboa MA, Balsinde J. Coordinate Regulation of TLR-Mediated Arachidonic Acid Mobilization in Macrophages by Group IVA and Group V Phospholipase A2s. J Immunol. 2009; 182: 3877-3883. doi: 10.4049/jimmunol.0804003 PMID: 19265167
-
(2009)
J Immunol
, vol.182
, pp. 3877-3883
-
-
Ruipérez, V.1
Astudillo, A.M.2
Balboa, M.A.3
Balsinde, J.4
-
27
-
-
0035929623
-
Atypical λ/ιPKC Conveys 5-Lipoxygenase/Leukotriene B4-mediated Cross-talk between Phospholipase A2s Regulating NF-κB Activation in Response to Tumor Necrosis Factor-α and Interleukin-1β
-
PMID: 11445585
-
Anthonsen MW, Andersen S, Solhaug A, Johansen B. Atypical λ/ιPKC Conveys 5-Lipoxygenase/Leukotriene B4-mediated Cross-talk between Phospholipase A2s Regulating NF-κB Activation in Response to Tumor Necrosis Factor-α and Interleukin-1β. J Biol Chem. 2001; 276: 35344-35351. PMID: 11445585
-
(2001)
J Biol Chem
, vol.276
, pp. 35344-35351
-
-
Anthonsen, M.W.1
Andersen, S.2
Solhaug, A.3
Johansen, B.4
-
28
-
-
64549150047
-
Amplification efficiency: Linking baseline and bias in the analysis of quantitative PCR data
-
PMID: 19237396
-
Ruijter JM, Ramakers C, Hoogaars WMH, Karlen Y, Bakker O, van den Hoff MJB, et al. Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data. Nucleic Acids Res. 2009; 37: e45. doi: 10.1093/nar/gkp045 PMID: 19237396
-
(2009)
Nucleic Acids Res
, vol.37
, pp. e45
-
-
Ruijter, J.M.1
Ramakers, C.2
Hoogaars, W.M.H.3
Karlen, Y.4
Bakker, O.5
Van Den Hoff, M.J.B.6
-
29
-
-
13444263475
-
Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells
-
PMID: 15670148
-
Masuda S, Murakami M, Komiyama K, Ishihara M, Ishikawa Y, Ishii T, et al. Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells. FEBS J. 2005; 272: 655-672. PMID: 15670148
-
(2005)
FEBS J
, vol.272
, pp. 655-672
-
-
Masuda, S.1
Murakami, M.2
Komiyama, K.3
Ishihara, M.4
Ishikawa, Y.5
Ishii, T.6
-
30
-
-
80053522828
-
Cytosolic phospholipase A2 induction and prostaglandin E2 release by interleukin-1β via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-κB activity in human rheumatoid arthritis synovial fibroblasts
-
PMID: 21702012
-
Chi PL, Luo SF, Hsieh HL, Lee IT, Hsiao LD, Chen YL, et al. Cytosolic phospholipase A2 induction and prostaglandin E2 release by interleukin-1β via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-κB activity in human rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 2011; 63: 2905-2917. doi: 10.1002/art.30504 PMID: 21702012
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2905-2917
-
-
Chi, P.L.1
Luo, S.F.2
Hsieh, H.L.3
Lee, I.T.4
Hsiao, L.D.5
Chen, Y.L.6
-
31
-
-
0034077207
-
Expression of cytosolic and secreted forms of phospholipase A2 and cyclooxygenases in human placenta, fetal membranes, and chorionic cell lines
-
PMID: 10751642
-
Johansen B, Rakkestad K, Balboa MA, Dennis EA. Expression of cytosolic and secreted forms of phospholipase A2 and cyclooxygenases in human placenta, fetal membranes, and chorionic cell lines. Prostaglandins Other Lipid Mediat. 2000; 60: 119-125. PMID: 10751642
-
(2000)
Prostaglandins Other Lipid Mediat
, vol.60
, pp. 119-125
-
-
Johansen, B.1
Rakkestad, K.2
Balboa, M.A.3
Dennis, E.A.4
-
32
-
-
21644470823
-
Identification of Novel Cytosolic Phospholipase A2s, Murine cPLA2δ, ε, and ζ, Which Form a Gene Cluster with cPLA2β
-
PMID: 15866882
-
Ohto T, Uozumi N, Hirabayashi T, Shimizu T. Identification of Novel Cytosolic Phospholipase A2s, Murine cPLA2δ, ε, and ζ, Which Form a Gene Cluster with cPLA2β. J Biol Chem. 2005; 280: 24576-24583. PMID: 15866882
-
(2005)
J Biol Chem
, vol.280
, pp. 24576-24583
-
-
Ohto, T.1
Uozumi, N.2
Hirabayashi, T.3
Shimizu, T.4
-
33
-
-
30344447530
-
Activation of Phospholipase A2 Is Associated with Generation of Placental Lipid Signals and Fetal Obesity
-
PMID: 16249288
-
Varastehpour A, Radaelli T, Minium J, Ortega H, Herrera E, Catalano P, et al. Activation of Phospholipase A2 Is Associated with Generation of Placental Lipid Signals and Fetal Obesity. J Clin Endocrinol Metab. 2006; 91: 248-255. PMID: 16249288
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 248-255
-
-
Varastehpour, A.1
Radaelli, T.2
Minium, J.3
Ortega, H.4
Herrera, E.5
Catalano, P.6
-
34
-
-
84904597974
-
Regulation of sPLA2-IID in Human Decidua: Insights Into the Complexity of the Prostaglandin Pathway in Labor
-
Mosher AA, Rainey KJ, Riley B, Levinson HS, Vinturache AE, Wood SL, et al. Regulation of sPLA2-IID in Human Decidua: Insights Into the Complexity of the Prostaglandin Pathway in Labor. Reprod Sci. 2014.
-
(2014)
Reprod Sci
-
-
Mosher, A.A.1
Rainey, K.J.2
Riley, B.3
Levinson, H.S.4
Vinturache, A.E.5
Wood, S.L.6
-
35
-
-
34547104852
-
Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2α activation
-
PMID: 17369491
-
Kikawada E, Bonventre JV, Arm JP. Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2α activation. Blood. 2007; 110: 561-567. PMID: 17369491
-
(2007)
Blood
, vol.110
, pp. 561-567
-
-
Kikawada, E.1
Bonventre, J.V.2
Arm, J.P.3
-
36
-
-
84907487577
-
Inhibition of Group IVA Cytosolic Phospholipase A2 by Thiazolyl Ketones In Vitro, Ex Vivo, and In Vivo
-
PMID: 25152071
-
Kokotos G, Feuerherm A, Barbayianni E, Shah I, Sæther M, Magrioti V, et al. Inhibition of Group IVA Cytosolic Phospholipase A2 by Thiazolyl Ketones In Vitro, Ex Vivo, and In Vivo. J Med Chem. 2014; 57: 7523-7535. doi: 10.1021/jm500192s PMID: 25152071
-
(2014)
J Med Chem
, vol.57
, pp. 7523-7535
-
-
Kokotos, G.1
Feuerherm, A.2
Barbayianni, E.3
Shah, I.4
Sæther, M.5
Magrioti, V.6
-
37
-
-
33646146486
-
Design and Synthesis of 1-Indol-1-yl-propan-2- ones as Inhibitors of Human Cytosolic Phospholipase A2α
-
PMID: 16610804
-
Ludwig J, Bovens S, Brauch C, Elfringhoff AS, Lehr M. Design and Synthesis of 1-Indol-1-yl-propan-2- ones as Inhibitors of Human Cytosolic Phospholipase A2α. J Med Chem. 2006; 49: 2611-2620. PMID: 16610804
-
(2006)
J Med Chem
, vol.49
, pp. 2611-2620
-
-
Ludwig, J.1
Bovens, S.2
Brauch, C.3
Elfringhoff, A.S.4
Lehr, M.5
-
38
-
-
84870556593
-
The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A2 and suppress prostaglandin E2 formation in mesangial cells
-
Huwiler A, Feuerherm AJ, Sakem B, Pastukhov O, Filipenko I, Nguyen T, et al. The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A2 and suppress prostaglandin E2 formation in mesangial cells. Br J Pharmacol. 2012; 168: 1691-1701.
-
(2012)
Br J Pharmacol
, vol.168
, pp. 1691-1701
-
-
Huwiler, A.1
Feuerherm, A.J.2
Sakem, B.3
Pastukhov, O.4
Filipenko, I.5
Nguyen, T.6
-
39
-
-
84892562024
-
Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes
-
PMID: 24349530
-
Sommerfelt RM, Feuerherm AJ, Jones K, Johansen B. Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes PLOS One. 2013; 8: e83555. doi: 10.1371/journal.pone.0083555 PMID: 24349530
-
(2013)
PLOS One
, vol.8
, pp. e83555
-
-
Sommerfelt, R.M.1
Feuerherm, A.J.2
Jones, K.3
Johansen, B.4
-
40
-
-
0027314633
-
Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2
-
PMID: 8018213
-
Street IP, Lin HK, Laliberté F, Ghomashchi F, Wang Z, Perrier H, et al. Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2. Biochemistry. 1993; 32: 5935-5940. PMID: 8018213
-
(1993)
Biochemistry
, vol.32
, pp. 5935-5940
-
-
Street, I.P.1
Lin, H.K.2
Laliberté, F.3
Ghomashchi, F.4
Wang, Z.5
Perrier, H.6
-
41
-
-
56349108542
-
Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A2 enzymes
-
PMID: 18993078
-
Antonopoulou G, Barbayianni E, Magrioti V, Cotton N, Stephens D, Constantinou-Kokotou V, et al. Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A2 enzymes. Bioorg Med Chem. 2008; 16: 10257-10269. doi: 10.1016/j.bmc.2008.10.046 PMID: 18993078
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 10257-10269
-
-
Antonopoulou, G.1
Barbayianni, E.2
Magrioti, V.3
Cotton, N.4
Stephens, D.5
Constantinou-Kokotou, V.6
-
42
-
-
0033022376
-
Pharmacology of LY315920/ S-5920, [[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A2Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI
-
PMID: 10027849
-
Snyder DW, Bach NJ, Dillard RD, Draheim SE, Carlson DG, Fox N, et al. Pharmacology of LY315920/ S-5920, [[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A2Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI. J Pharmacol Exp Ther. 1999; 288: 1117-1124. PMID: 10027849
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 1117-1124
-
-
Snyder, D.W.1
Bach, N.J.2
Dillard, R.D.3
Draheim, S.E.4
Carlson, D.G.5
Fox, N.6
-
43
-
-
0035839557
-
Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and interleukin-1beta-induced NF-kappa B activation
-
PMID: 11390371
-
Anthonsen MW, Solhaug A, Johansen B. Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and interleukin-1beta-induced NF-kappa B activation. J Biol Chem. 2001; 276: 30527-30536. PMID: 11390371
-
(2001)
J Biol Chem
, vol.276
, pp. 30527-30536
-
-
Anthonsen, M.W.1
Solhaug, A.2
Johansen, B.3
-
44
-
-
33947545388
-
The Toll-Like Receptor Adaptor Proteins MyD88 and Mal/TIRAP Contribute to the Inflammatory and Destructive Processes in a Human Model of Rheumatoid Arthritis
-
PMID: 17255320
-
Sacre SM, Andreakos E, Kiriakidis S, Amjadi P, Lundberg A, Giddins G, et al. The Toll-Like Receptor Adaptor Proteins MyD88 and Mal/TIRAP Contribute to the Inflammatory and Destructive Processes in a Human Model of Rheumatoid Arthritis. Am J Pathol. 2007; 170: 518-525. PMID: 17255320
-
(2007)
Am J Pathol
, vol.170
, pp. 518-525
-
-
Sacre, S.M.1
Andreakos, E.2
Kiriakidis, S.3
Amjadi, P.4
Lundberg, A.5
Giddins, G.6
-
45
-
-
0037333990
-
Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling
-
PMID: 12632416
-
Kyburz D, Rethage J, Seibl R, Lauener R, Gay RE, Carson DA, et al. Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling. Arthritis Rheum. 2003; 48: 642-650. PMID: 12632416
-
(2003)
Arthritis Rheum
, vol.48
, pp. 642-650
-
-
Kyburz, D.1
Rethage, J.2
Seibl, R.3
Lauener, R.4
Gay, R.E.5
Carson, D.A.6
-
46
-
-
67349167059
-
Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay
-
PMID: 19322177
-
Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T, et al. Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature. 2009; 458: 1185-1190. doi: 10.1038/nature07924 PMID: 19322177
-
(2009)
Nature
, vol.458
, pp. 1185-1190
-
-
Matsushita, K.1
Takeuchi, O.2
Standley, D.M.3
Kumagai, Y.4
Kawagoe, T.5
Miyake, T.6
-
47
-
-
0036152971
-
Lipopolysaccharide-induced release of arachidonic acid and prostaglandins in liver macrophages: Regulation by Group IV cytosolic phospholipase A2, but not by Group V and Group IIA secretory phospholipase A2
-
PMID: 11812647
-
Dieter P, Kolada A, Kamionka S, Schadow A, Kaszkin M. Lipopolysaccharide-induced release of arachidonic acid and prostaglandins in liver macrophages: Regulation by Group IV cytosolic phospholipase A2, but not by Group V and Group IIA secretory phospholipase A2. Cell Signal. 2002; 14: 199-204. PMID: 11812647
-
(2002)
Cell Signal
, vol.14
, pp. 199-204
-
-
Dieter, P.1
Kolada, A.2
Kamionka, S.3
Schadow, A.4
Kaszkin, M.5
-
48
-
-
0032493367
-
Functional coupling between secretory phospholipase A2 and cy-clooxygenase- 2 and its regulation by cytosolic group IV phospholipase A2
-
PMID: 9653121
-
Balsinde J, Balboa MA, Dennis EA. Functional coupling between secretory phospholipase A2 and cy-clooxygenase- 2 and its regulation by cytosolic group IV phospholipase A2. Proc Natl Acad Sci U S A. 1998; 95: 7951-7956. PMID: 9653121
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7951-7956
-
-
Balsinde, J.1
Balboa, M.A.2
Dennis, E.A.3
-
49
-
-
0026710625
-
Interleukin-1β stimulates cytosolic phospholipase A2 in rheumatoid synovial fibroblasts
-
PMID: 1575744
-
Hulkower KI, Hope WC, Chen T, Anderson CM, Coffey JW, Morgan DW. Interleukin-1β stimulates cytosolic phospholipase A2 in rheumatoid synovial fibroblasts. Biochem Biophys Res Commun. 1992; 184: 712-718. PMID: 1575744
-
(1992)
Biochem Biophys Res Commun
, vol.184
, pp. 712-718
-
-
Hulkower, K.I.1
Hope, W.C.2
Chen, T.3
Anderson, C.M.4
Coffey, J.W.5
Morgan, D.W.6
-
50
-
-
60249099795
-
Varespladib (A-002), a Secretory Phospholipase A2 Inhibitor, Reduces Atherosclerosis and Aneurysm Formation in ApoE-/- Mice
-
PMID: 19129734
-
Fraser H, Hislop C, Christie RM, Rick HL, Reidy CA, Chouinard ML, et al. Varespladib (A-002), a Secretory Phospholipase A2 Inhibitor, Reduces Atherosclerosis and Aneurysm Formation in ApoE-/- Mice. J Cardiovasc Pharmacol. 2009; 53: 60-65 doi: 10.1097/FJC.0b013e318195bfbc PMID: 19129734
-
(2009)
J Cardiovasc Pharmacol
, vol.53
, pp. 60-65
-
-
Fraser, H.1
Hislop, C.2
Christie, R.M.3
Rick, H.L.4
Reidy, C.A.5
Chouinard, M.L.6
-
51
-
-
79952080909
-
Recent progress in phospholipase A2 research: From cells to animals to humans
-
PMID: 21185866
-
Murakami M, Taketomi Y, Miki Y, Sato H, Hirabayashi T, Yamamoto K. Recent progress in phospholipase A2 research: From cells to animals to humans. Prog Lipid Res. 2011; 50: 152-192. doi: 10.1016/j.plipres.2010.12.001 PMID: 21185866
-
(2011)
Prog Lipid Res
, vol.50
, pp. 152-192
-
-
Murakami, M.1
Taketomi, Y.2
Miki, Y.3
Sato, H.4
Hirabayashi, T.5
Yamamoto, K.6
-
52
-
-
0034739445
-
Calcium-independent phospholipase A2: Structure and function
-
PMID: 11080674
-
Winstead MV, Balsinde J, Dennis EA. Calcium-independent phospholipase A2: structure and function. Biochim Biophys Acta. 2000; 1488: 28-39. PMID: 11080674
-
(2000)
Biochim Biophys Acta
, vol.1488
, pp. 28-39
-
-
Winstead, M.V.1
Balsinde, J.2
Dennis, E.A.3
-
53
-
-
0036229958
-
Specific cyclooxygenase-2 inhibitors: What have we learned since they came into widespread clinical use?
-
PMID: 11981317
-
Crofford LJ. Specific cyclooxygenase-2 inhibitors: what have we learned since they came into widespread clinical use? Curr Opin Rheumatol. 2002; 14: 225-230. PMID: 11981317
-
(2002)
Curr Opin Rheumatol
, vol.14
, pp. 225-230
-
-
Crofford, L.J.1
-
54
-
-
84855384226
-
TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes
-
PMID: 22105995
-
Philippe L, Alsaleh G, Suffert G, Meyer A, Georgel P, Sibilia J, et al. TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes. J Immunol. 2012; 188: 454-461. doi: 10.4049/jimmunol.1102348 PMID: 22105995
-
(2012)
J Immunol
, vol.188
, pp. 454-461
-
-
Philippe, L.1
Alsaleh, G.2
Suffert, G.3
Meyer, A.4
Georgel, P.5
Sibilia, J.6
-
55
-
-
77955096184
-
Therapeutic targets in rheumatoid arthritis: The interleukin-6 receptor
-
PMID: 19854855
-
Choy E, Dayer JM. Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor. Rheumatology. 2010; 49: 15-24. doi: 10.1093/rheumatology/kep329 PMID: 19854855
-
(2010)
Rheumatology
, vol.49
, pp. 15-24
-
-
Choy, E.1
Dayer, J.M.2
-
56
-
-
0344534939
-
Soluble interleukin 6 (IL-6) receptor and IL-6 levels in serum and synovial fluid of patients with different arthropathies
-
PMID: 9375862
-
Usón J, Balsa A, Pascual-Salcedo D, Cabezas JA, Gonzalez-Tarrio JM, Martín-Mola E, et al. Soluble interleukin 6 (IL-6) receptor and IL-6 levels in serum and synovial fluid of patients with different arthropathies. J Rheumatol. 1997; 24: 2069-2075. PMID: 9375862
-
(1997)
J Rheumatol
, vol.24
, pp. 2069-2075
-
-
Usón, J.1
Balsa, A.2
Pascual-Salcedo, D.3
Cabezas, J.A.4
Gonzalez-Tarrio, J.M.5
Martín-Mola, E.6
-
57
-
-
0030903094
-
The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis
-
PMID: 9182920
-
Okamoto H, Yamamura M, Morita Y, Harada S, Makino H, Ota Z. The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis. Arthritis Rheum. 1997; 40: 1096-1105. PMID: 9182920
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1096-1105
-
-
Okamoto, H.1
Yamamura, M.2
Morita, Y.3
Harada, S.4
Makino, H.5
Ota, Z.6
-
58
-
-
0032536542
-
Interleukin 6 Is Required for the Development of Collagen-induced Arthritis
-
PMID: 9463396
-
Alonzi T, Fattori E, Lazzaro D, Costa P, Probert L, Kollias G, et al. Interleukin 6 Is Required for the Development of Collagen-induced Arthritis. J Exp Med. 1998; 187: 461-468. PMID: 9463396
-
(1998)
J Exp Med
, vol.187
, pp. 461-468
-
-
Alonzi, T.1
Fattori, E.2
Lazzaro, D.3
Costa, P.4
Probert, L.5
Kollias, G.6
-
59
-
-
0033503152
-
Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice
-
PMID: 10446862
-
Sasai M, Saeki Y, Ohshima S, Nishioka K, Mima T, Tanaka T, et al. Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice. Arthritis Rheum. 1999; 42: 1635-1643. PMID: 10446862
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1635-1643
-
-
Sasai, M.1
Saeki, Y.2
Ohshima, S.3
Nishioka, K.4
Mima, T.5
Tanaka, T.6
-
60
-
-
0032429668
-
Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis
-
PMID: 9870868
-
Takagi N, Mihara M, Moriya Y, Nishimoto N, Yoshizaki K, Kishimoto T, et al. Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis. Arthritis Rheum. 1998; 41: 2117-2121. PMID: 9870868
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2117-2121
-
-
Takagi, N.1
Mihara, M.2
Moriya, Y.3
Nishimoto, N.4
Yoshizaki, K.5
Kishimoto, T.6
-
61
-
-
84877871136
-
Exposure-response relationship of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in a large population of patients with rheumatoid arthritis
-
PMID: 23436260
-
Levi M, Grange S, Frey N. Exposure-response relationship of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in a large population of patients with rheumatoid arthritis. J Clin Pharmacol. 2013; 53: 151-159. doi: 10.1177/0091270012437585 PMID: 23436260
-
(2013)
J Clin Pharmacol
, vol.53
, pp. 151-159
-
-
Levi, M.1
Grange, S.2
Frey, N.3
-
62
-
-
33749363027
-
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
-
PMID: 16947782
-
Maini RN, Taylor PC, Szechinski J, Pavelka K, Bröll J, Balint G, et al. Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum. 2006; 54: 2817-2829. PMID: 16947782
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2817-2829
-
-
Maini, R.N.1
Taylor, P.C.2
Szechinski, J.3
Pavelka, K.4
Bröll, J.5
Balint, G.6
-
63
-
-
0036015185
-
Regulation by PGE2 of the production of interleukin-6, macrophage colony stimulating factor, and vascular endothelial growth factor in human synovial fibroblasts
-
PMID: 12010778
-
Inoue H, Takamori M, Shimoyama Y, Ishibashi H, Yamamoto S, Koshihara Y. Regulation by PGE2 of the production of interleukin-6, macrophage colony stimulating factor, and vascular endothelial growth factor in human synovial fibroblasts. Br J Pharmacol. 2002; 136: 287-295. PMID: 12010778
-
(2002)
Br J Pharmacol
, vol.136
, pp. 287-295
-
-
Inoue, H.1
Takamori, M.2
Shimoyama, Y.3
Ishibashi, H.4
Yamamoto, S.5
Koshihara, Y.6
-
64
-
-
33344465869
-
Prostacyclin-IP signaling and prostaglandin E2-EP2/ EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis
-
PMID: 16446378
-
Honda T, Segi-Nishida E, Miyachi Y, Narumiya S. Prostacyclin-IP signaling and prostaglandin E2-EP2/ EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis. J Exp Med. 2006; 203: 325-335. PMID: 16446378
-
(2006)
J Exp Med
, vol.203
, pp. 325-335
-
-
Honda, T.1
Segi-Nishida, E.2
Miyachi, Y.3
Narumiya, S.4
-
65
-
-
84879885593
-
The anti-inflammatory effect of cyclooxygenase inhibitors in fibroblast-like synoviocytes from the human temporomandibular joint results from the suppression of PGE2 production
-
PMID: 23331485
-
Kawashima M, Ogura N, Akutsu M, Ito K, Kondoh T. The anti-inflammatory effect of cyclooxygenase inhibitors in fibroblast-like synoviocytes from the human temporomandibular joint results from the suppression of PGE2 production. J Oral Pathol Med. 2013; 42: 499-506. doi: 10.1111/jop.12045 PMID: 23331485
-
(2013)
J Oral Pathol Med
, vol.42
, pp. 499-506
-
-
Kawashima, M.1
Ogura, N.2
Akutsu, M.3
Ito, K.4
Kondoh, T.5
-
66
-
-
70249085277
-
Prostaglandin E2 Differentially Modulates Proinflammatory/Prodestructive Effects of TNF-α on Synovial Fibroblasts via Specific E Prostanoid Receptors/cAMP
-
PMID: 19542367
-
Kunisch E, Jansen A, Kojima F, Löffler I, Kapoor M, Kawai S, et al. Prostaglandin E2 Differentially Modulates Proinflammatory/Prodestructive Effects of TNF-α on Synovial Fibroblasts via Specific E Prostanoid Receptors/cAMP. J Immunol. 2009; 183: 1328-1336. doi: 10.4049/jimmunol.0900801 PMID: 19542367
-
(2009)
J Immunol
, vol.183
, pp. 1328-1336
-
-
Kunisch, E.1
Jansen, A.2
Kojima, F.3
Löffler, I.4
Kapoor, M.5
Kawai, S.6
-
67
-
-
0035147088
-
Regulation of angiogenesis by the C-X-C chemokines interleukin-8 and epithelial neutrophil activating peptide 78 in the rheumatoid joint
-
PMID: 11212173
-
Koch AE, Volin MV, Woods JM, Kunkel SL, Connors MA, Harlow LA, et al. Regulation of angiogenesis by the C-X-C chemokines interleukin-8 and epithelial neutrophil activating peptide 78 in the rheumatoid joint. Arthritis Rheum. 2001; 44: 31-40. PMID: 11212173
-
(2001)
Arthritis Rheum
, vol.44
, pp. 31-40
-
-
Koch, A.E.1
Volin, M.V.2
Woods, J.M.3
Kunkel, S.L.4
Connors, M.A.5
Harlow, L.A.6
-
68
-
-
0035080352
-
Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8
-
PMID: 11178119
-
Hayashida K, Nank T, Girschick H, Yavuz S, Ochi T, Lipsky PE. Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8. Arthritis Res. 2001; 3: 118-126. PMID: 11178119
-
(2001)
Arthritis Res
, vol.3
, pp. 118-126
-
-
Hayashida, K.1
Nank, T.2
Girschick, H.3
Yavuz, S.4
Ochi, T.5
Lipsky, P.E.6
-
69
-
-
0033127746
-
The participation of IL-8 in the synovial lesions at an early stage of rheumatoid arthritis
-
PMID: 10494903
-
Takahashi Y, Kasahara T, Sawai T, Rikimaru A, Mukaida N, Matsushima K, et al. The participation of IL-8 in the synovial lesions at an early stage of rheumatoid arthritis. Tohoku J Exp Med. 1999; 188: 75-87. PMID: 10494903
-
(1999)
Tohoku J Exp Med
, vol.188
, pp. 75-87
-
-
Takahashi, Y.1
Kasahara, T.2
Sawai, T.3
Rikimaru, A.4
Mukaida, N.5
Matsushima, K.6
-
70
-
-
0028009807
-
Localisation of interleukin 8 in the synovial membrane, cartilage-pannus junction and chondrocytes in rheumatoid arthritis
-
PMID: 8108662
-
Deleuran B, Lemche P, Kristensen M, Chu CQ, Field M, Jensen J, et al. Localisation of interleukin 8 in the synovial membrane, cartilage-pannus junction and chondrocytes in rheumatoid arthritis. Scand J Rheumatol. 1994; 23: 2-7. PMID: 8108662
-
(1994)
Scand J Rheumatol
, vol.23
, pp. 2-7
-
-
Deleuran, B.1
Lemche, P.2
Kristensen, M.3
Chu, C.Q.4
Field, M.5
Jensen, J.6
-
71
-
-
10344233226
-
Cytosolic phospholipase A2 group IVα but not secreted phospholipase A2 group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors ã 1 and 2 in human lung cells
-
PMID: 15331599
-
Pawliczak R, Logun C, Madara P, Lawrence M, Woszczek G, Ptasinska A, et al. Cytosolic phospholipase A2 group IVα but not secreted phospholipase A2 group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors ã 1 and 2 in human lung cells. J Biol Chem. 2004; 279: 48550-48561. PMID: 15331599
-
(2004)
J Biol Chem
, vol.279
, pp. 48550-48561
-
-
Pawliczak, R.1
Logun, C.2
Madara, P.3
Lawrence, M.4
Woszczek, G.5
Ptasinska, A.6
-
72
-
-
58149214306
-
Reduction of cPLA2a overexpression: An efficient anti-inflammatory therapy for collagen-induced arthritis
-
PMID: 18825749
-
Raichel L, Berger S, Hadad N, Kachko L, Karter M, Szaingurten-Solodkin I, et al. Reduction of cPLA2a overexpression: An efficient anti-inflammatory therapy for collagen-induced arthritis. Eur J Immunol. 2008; 38: 2905-2915. doi: 10.1002/eji.200838545 PMID: 18825749
-
(2008)
Eur J Immunol
, vol.38
, pp. 2905-2915
-
-
Raichel, L.1
Berger, S.2
Hadad, N.3
Kachko, L.4
Karter, M.5
Szaingurten-Solodkin, I.6
|