Prostaglandin E2 differentially modulates proinflammatory/ prodestructive effects of TNF-α on synovial fibroblasts via specific E prostanoid receptors/cAMP

Journal of Immunology

Volumn 183, Issue 2, 2009, Pages 1328-1336

  Kunisch, Elke ^a   Jansen, Anne ^a,b   Kojima, Fumiaki ^b   Löffler, Ivonne ^a,c   Kapoor, Mohit ^b   Kawai, Shinichi ^d   Rubio, Ignacio ^c   Crofford, Leslie J ^b   Kinne, Raimund W ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY OF KENTUCKY   (United States)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BUTAPROST; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; E PROSTANOID RECEPTOR; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; PROSTANOID RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN SYNTHASE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME RELEASE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; DRUG POTENTIATION; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECRETION; SYNOVIUM;

ARTHRITIS, RHEUMATOID; CYCLIC AMP; DINOPROSTONE; FIBROBLASTS; HUMANS; INFLAMMATION; INTERLEUKIN-6; MATRIX METALLOPROTEINASE 1; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, PROSTAGLANDIN E; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70249085277     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900801     Document Type: Article

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