Sphingolipid metabolism correlates with cerebrospinal fluid beta amyloid levels in Alzheimer's disease

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Fonteh, Alfred N ^a   Ormseth, Cora ^a,b   Chiang, Jiarong ^a,c   Cipolla, Matthew ^a   Arakaki, Xianghong ^a   Harrington, Michael G ^a  

^a HUNTINGTON MEDICAL RESEARCH INSTITUTES   (United States)

^b YALE UNIVERSITY   (United States)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; ANTIDEPRESSANT AGENT; BIOLOGICAL MARKER; CERAMIDE; DIHYDROCERAMIDE; GLYCOSPHINGOLIPID; NANOPARTICLE; PSYCHOTROPIC AGENT; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CELL MEMBRANE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DEPRESSION; DIAGNOSTIC TEST ACCURACY STUDY; DRUG USE; ENZYME ACTIVITY; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; PREDICTIVE VALUE; PROTEIN CEREBROSPINAL FLUID LEVEL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SPHINGOLIPID METABOLISM; SUPERNATANT FLUID; TANDEM MASS SPECTROMETRY; COGNITION; DEMENTIA; ENZYME ACTIVATION; GENETICS; GENOTYPE; MASS SPECTROMETRY; METABOLISM; MIDDLE AGED; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEINS E; BIOMARKERS; COGNITION; DEMENTIA; ENZYME ACTIVATION; FEMALE; GENOTYPE; HUMANS; MALE; MASS SPECTROMETRY; MIDDLE AGED; ROC CURVE; SENSITIVITY AND SPECIFICITY; SPHINGOLIPIDS; SPHINGOMYELIN PHOSPHODIESTERASE; TAU PROTEINS;

EID: 84929120210     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125597     Document Type: Article

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