-
1
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
Hannun, Y. A. and Obeid, L. M. (2008) Principles of bioactive lipid signalling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9, 139-150
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
2
-
-
66349086742
-
Bioactive sphingolipids: Metabolism and function
-
Bartke, N. and Hannun, Y. A. (2009) Bioactive sphingolipids: metabolism and function. J. Lipid Res. 50, S91-S96
-
(2009)
J. Lipid Res.
, vol.50
-
-
Bartke, N.1
Hannun, Y.A.2
-
3
-
-
66349124729
-
Sphingosine-1-phosphate: The Swiss army knife of sphingolipid signaling
-
Maceyka, M., Milstien, S. and Spiegel, S. (2009) Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling. J. Lipid Res. 50, S272-S276
-
(2009)
J. Lipid Res.
, vol.50
-
-
Maceyka, M.1
Milstien, S.2
Spiegel, S.3
-
4
-
-
42249105215
-
The sphingolipid salvage pathway in ceramide metabolism and signaling
-
Kitatani, K., Idkowiak-Baldys, J. and Hannun, Y. A. (2008) The sphingolipid salvage pathway in ceramide metabolism and signaling. Cell. Signalling 20, 1010-1018
-
(2008)
Cell. Signalling
, vol.20
, pp. 1010-1018
-
-
Kitatani, K.1
Idkowiak-Baldys, J.2
Hannun, Y.A.3
-
5
-
-
0030963660
-
Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5- Trans-double bond of sphingosine at the level of dihydroceramide
-
Michel, C., van Echten-Deckert, G., Rother, J., Sandhoff, K., Wang, E. and Merrill, Jr, A. H. (1997) Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5- trans-double bond of sphingosine at the level of dihydroceramide. J. Biol. Chem. 272, 22432-22437
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22432-22437
-
-
Michel, C.1
Van Echten-Deckert, G.2
Rother, J.3
Sandhoff, K.4
Wang, E.5
Merrill Jr., A.H.6
-
6
-
-
0030660670
-
Conversion of dihydroceramide into ceramide: Involvement of a desaturase
-
Geeraert, L., Mannaerts, G. P. and van Veldhoven, P. P. (1997) Conversion of dihydroceramide into ceramide: involvement of a desaturase. Biochem. J. 327, 125-132 (Pubitemid 27455469)
-
(1997)
Biochemical Journal
, vol.327
, Issue.1
, pp. 125-132
-
-
Geeraert, L.1
Mannaerts, G.P.2
Van Veldhoven, P.P.3
-
7
-
-
0037067746
-
Identification and characterization of a sphingolipid Δ4-desaturase family
-
Ternes, P., Franke, S., Zahringer, U., Sperling, P. and Heinz, E. (2002) Identification and characterization of a sphingolipid Δ4-desaturase family. J. Biol. Chem. 277, 25512-25518
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25512-25518
-
-
Ternes, P.1
Franke, S.2
Zahringer, U.3
Sperling, P.4
Heinz, E.5
-
8
-
-
0034142185
-
Role of highly conserved residues in the reaction catalyzed by recombinant Δ7-sterol-C5(6)-desaturase studied by site-directed mutagenesis
-
Taton, M., Husselstein, T., Benveniste, P. and Rahier, A. (2000) Role of highly conserved residues in the reaction catalyzed by recombinant Δ7-sterol-C5(6)-desaturase studied by site-directed mutagenesis. Biochemistry 39, 701-711
-
(2000)
Biochemistry
, vol.39
, pp. 701-711
-
-
Taton, M.1
Husselstein, T.2
Benveniste, P.3
Rahier, A.4
-
9
-
-
0345708282
-
Structure-function studies of yeast C-4 sphingolipid long chain base hydroxylase
-
Idkowiak-Baldys, J., Takemoto, J. Y. and Grilley, M. M. (2003) Structure-function studies of yeast C-4 sphingolipid long chain base hydroxylase. Biochim. Biophys. Acta 1618, 17-24
-
(2003)
Biochim. Biophys. Acta
, vol.1618
, pp. 17-24
-
-
Idkowiak-Baldys, J.1
Takemoto, J.Y.2
Grilley, M.M.3
-
10
-
-
34447115107
-
Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells
-
Kraveka, J. M., Li, L., Szulc, Z. M., Bielawski, J., Ogretmen, B., Hannun, Y. A., Obeid, L. M. and Bielawska, A. (2007) Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells. J. Biol. Chem. 282, 16718-16728
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16718-16728
-
-
Kraveka, J.M.1
Li, L.2
Szulc, Z.M.3
Bielawski, J.4
Ogretmen, B.5
Hannun, Y.A.6
Obeid, L.M.7
Bielawska, A.8
-
11
-
-
33745028656
-
Dihydroceramide hinders ceramide channel formation: Implications on apoptosis
-
DOI 10.1007/s10495-006-5882-8
-
Stiban, J., Fistere, D. and Colombini, M. (2006) Dihydroceramide hinders ceramide channel formation: implications on apoptosis. Apoptosis 11, 773-780 (Pubitemid 43876846)
-
(2006)
Apoptosis
, vol.11
, Issue.5
, pp. 773-780
-
-
Stiban, J.1
Fistere, D.2
Colombini, M.3
-
12
-
-
67649920937
-
Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells
-
Signorelli, P., Munoz-Olaya, J. M., Gagliostro, V., Casas, J., Ghidoni, R. and Fabrias, G. (2009) Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells. Cancer Lett. 282, 238-243
-
(2009)
Cancer Lett.
, vol.282
, pp. 238-243
-
-
Signorelli, P.1
Munoz-Olaya, J.M.2
Gagliostro, V.3
Casas, J.4
Ghidoni, R.5
Fabrias, G.6
-
13
-
-
33845336495
-
Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
-
Zheng, W., Kollmeyer, J., Symolon, H., Momin, A., Munter, E., Wang, E., Kelly, S., Allegood, J. C., Liu, Y., Peng, Q. et al. (2006) Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochim. Biophys. Acta 1758, 1864-1884
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 1864-1884
-
-
Zheng, W.1
Kollmeyer, J.2
Symolon, H.3
Momin, A.4
Munter, E.5
Wang, E.6
Kelly, S.7
Allegood, J.C.8
Liu, Y.9
Peng, Q.10
-
14
-
-
11144239577
-
γ-Tocopherol or combinations of vitamin e forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis
-
Jiang, Q., Wong, J., Fyrst, H., Saba, J. D. and Ames, B. N. (2004) γ-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. Proc. Natl. Acad. Sci. U.S.A. 101, 17825-17830
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 17825-17830
-
-
Jiang, Q.1
Wong, J.2
Fyrst, H.3
Saba, J.D.4
Ames, B.N.5
-
15
-
-
0031595243
-
Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR)
-
DiPietrantonio, A. M., Hsieh, T. C., Olson, S. C. and Wu, J. M. (1998) Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR). Int. J. Cancer 78, 53-61
-
(1998)
Int. J. Cancer
, vol.78
, pp. 53-61
-
-
DiPietrantonio, A.M.1
Hsieh, T.C.2
Olson, S.C.3
Wu, J.M.4
-
16
-
-
1542713521
-
N-(4-hydroxyphenyl)retinamide induces growth arrest and apoptosis in HTLV-I-transformed cells
-
Darwiche, N., Hatoum, A., Dbaibo, G., Kadara, H., Nasr, R., Abou-Lteif, G., Bazzi, R., Hermine, O., de The, H. and Bazarbachi, A. (2004) N-(4-hydroxyphenyl)retinamide induces growth arrest and apoptosis in HTLV-I-transformed cells. Leukemia 18, 607-615
-
(2004)
Leukemia
, vol.18
, pp. 607-615
-
-
Darwiche, N.1
Hatoum, A.2
Dbaibo, G.3
Kadara, H.4
Nasr, R.5
Abou-Lteif, G.6
Bazzi, R.7
Hermine, O.8
De The, H.9
Bazarbachi, A.10
-
17
-
-
40949107961
-
Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells
-
Tiwari, M., Bajpai, V. K., Sahasrabuddhe, A. A., Kumar, A., Sinha, R. A., Behari, S. and Godbole, M. M. (2008) Inhibition of N-(4-hydroxyphenyl) retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells. Carcinogenesis 29, 600-609
-
(2008)
Carcinogenesis
, vol.29
, pp. 600-609
-
-
Tiwari, M.1
Bajpai, V.K.2
Sahasrabuddhe, A.A.3
Kumar, A.4
Sinha, R.A.5
Behari, S.6
Godbole, M.M.7
-
18
-
-
0038311699
-
Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma
-
Lovat, P. E., Ranalli, M., Corazzari, M., Raffaghello, L., Pearson, A. D., Ponzoni, M., Piacentini, M., Melino, G. and Redfern, C. P. (2003) Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma. J. Cell. Biochem. 89, 698-708
-
(2003)
J. Cell. Biochem.
, vol.89
, pp. 698-708
-
-
Lovat, P.E.1
Ranalli, M.2
Corazzari, M.3
Raffaghello, L.4
Pearson, A.D.5
Ponzoni, M.6
Piacentini, M.7
Melino, G.8
Redfern, C.P.9
-
19
-
-
33846549131
-
Reactive oxygen species mediate N-(4-hydroxyphenyl)retinamide-induced cell death in malignant T-cells and are inhibited by the HTLV-I oncoprotein Tax
-
Darwiche, N., Abou-Lteif, G. and Bazarbachi, A. (2007) Reactive oxygen species mediate N-(4-hydroxyphenyl)retinamide-induced cell death in malignant T-cells and are inhibited by the HTLV-I oncoprotein Tax. Leukemia 21, 261-269
-
(2007)
Leukemia
, vol.21
, pp. 261-269
-
-
Darwiche, N.1
Abou-Lteif, G.2
Bazarbachi, A.3
-
20
-
-
33847185842
-
A redox cycle within the cell cycle: Ring in the old with the new
-
Menon, S. G. and Goswami, P. C. (2007) A redox cycle within the cell cycle: ring in the old with the new. Oncogene 26, 1101-1109
-
(2007)
Oncogene
, vol.26
, pp. 1101-1109
-
-
Menon, S.G.1
Goswami, P.C.2
-
21
-
-
70449133798
-
Redox control of the cell cycle in health and disease
-
Sarsour, E., Kumar, M. G., Chaudhuri, L., Kalen, A. L. and Goswami, P. (2009) Redox control of the cell cycle in health and disease. Antioxid. Redox Signal. 11, 2985-3011
-
(2009)
Antioxid. Redox Signal.
, vol.11
, pp. 2985-3011
-
-
Sarsour, E.1
Kumar, M.G.2
Chaudhuri, L.3
Kalen, A.L.4
Goswami, P.5
-
22
-
-
70349799010
-
The cell cycle is a redox cycle: Linking phase-specific targets to cell fate
-
Burhans, W. C. and Heintz, N. H. (2009) The cell cycle is a redox cycle: Linking phase-specific targets to cell fate. Free Radical Biol. Med. 47, 1282-1293
-
(2009)
Free Radical Biol. Med.
, vol.47
, pp. 1282-1293
-
-
Burhans, W.C.1
Heintz, N.H.2
-
23
-
-
33748757219
-
Tailoring structure-function and targeting properties of ceramides by site-specific cationization
-
Szulc, Z. M., Bielawski, J., Gracz, H., Gustilo, M., Mayroo, N., Hannun, Y. A., Obeid, L. M. and Bielawska, A. (2006) Tailoring structure-function and targeting properties of ceramides by site-specific cationization. Bioorg. Med. Chem. 14, 7083-7104
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 7083-7104
-
-
Szulc, Z.M.1
Bielawski, J.2
Gracz, H.3
Gustilo, M.4
Mayroo, N.5
Hannun, Y.A.6
Obeid, L.M.7
Bielawska, A.8
-
24
-
-
27344460719
-
Preparation of intact microsomes from cultured mammalian H4IIE cells
-
Sukhodub, A. L. and Burchell, A. (2005) Preparation of intact microsomes from cultured mammalian H4IIE cells. J. Pharmacol. Toxicol. Methods 52, 330-334
-
(2005)
J. Pharmacol. Toxicol. Methods
, vol.52
, pp. 330-334
-
-
Sukhodub, A.L.1
Burchell, A.2
-
25
-
-
0032716071
-
Dihydroceramide desaturase
-
Schulze, H., Michel, C. and van Echten-Deckert, G. (2000) Dihydroceramide desaturase. Methods Enzymol. 311, 22-30
-
(2000)
Methods Enzymol.
, vol.311
, pp. 22-30
-
-
Schulze, H.1
Michel, C.2
Van Echten-Deckert, G.3
-
26
-
-
1542346129
-
NADPH dependent activation of microsomal glutathione transferase 1
-
Rinaldi, R., Aniya, Y., Svensson, R., Eliasson, E., Swedmark, S., Shimoji, M. and Morgenstern, R. (2004) NADPH dependent activation of microsomal glutathione transferase 1. Chem. Biol. Interact. 147, 163-172
-
(2004)
Chem. Biol. Interact.
, vol.147
, pp. 163-172
-
-
Rinaldi, R.1
Aniya, Y.2
Svensson, R.3
Eliasson, E.4
Swedmark, S.5
Shimoji, M.6
Morgenstern, R.7
-
27
-
-
33746271951
-
Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
-
26a Bielawski, J., Szulc, Z. M., Hannun, Y. A. and Bielawska, A. (2006) Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods 39, 82-91
-
(2006)
Methods
, vol.39
, pp. 82-91
-
-
Bielawski, J.1
Szulc, Z.M.2
Hannun, Y.A.3
Bielawska, A.4
-
28
-
-
0031783829
-
2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells
-
2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells. J. Cell Sci. 111, 3209-3220
-
(1998)
J. Cell Sci.
, vol.111
, pp. 3209-3220
-
-
Goldkorn, T.1
Balaban, N.2
Shannon, M.3
Chea, V.4
Matsukuma, K.5
Gilchrist, D.6
Wang, H.7
Chan, C.8
-
30
-
-
0035198813
-
Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione
-
Lavrentiadou, S. N., Chan, C., Kawcak, T., Ravid, T., Tsaba, A., van der Vliet, A., Rasooly, R. and Goldkorn, T. (2001) Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. Am. J. Respir. Cell Mol. Biol. 25, 676-684
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.25
, pp. 676-684
-
-
Lavrentiadou, S.N.1
Chan, C.2
Kawcak, T.3
Ravid, T.4
Tsaba, A.5
Van Der Vliet, A.6
Rasooly, R.7
Goldkorn, T.8
-
31
-
-
0021893435
-
Vitamin K3 inhibition of malignant murine cell growth and human tumor colony formation
-
Chlebowski, R. T., Dietrich, M., Akman, S. and Block, J. B. (1985) Vitamin K3 inhibition of malignant murine cell growth and human tumor colony formation. Cancer Treat. Rep. 69, 527-532
-
(1985)
Cancer Treat. Rep.
, vol.69
, pp. 527-532
-
-
Chlebowski, R.T.1
Dietrich, M.2
Akman, S.3
Block, J.B.4
-
32
-
-
37849043898
-
Reversible inhibition of α-ketoglutarate dehydrogenase by hydrogen peroxide: Glutathionylation and protection of lipoic acid
-
Applegate, M. A., Humphries, K. M. and Szweda, L. I. (2008) Reversible inhibition of α-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid. Biochemistry 47, 473-478
-
(2008)
Biochemistry
, vol.47
, pp. 473-478
-
-
Applegate, M.A.1
Humphries, K.M.2
Szweda, L.I.3
-
33
-
-
53149120605
-
Glucose metabolism is accelerated by exposure to t-butylhydroperoxide during NADH consumption in human erythrocytes
-
Ogasawara, Y., Funakoshi, M. and Ishii, K. (2008) Glucose metabolism is accelerated by exposure to t-butylhydroperoxide during NADH consumption in human erythrocytes. Blood Cells Mol. Dis. 41, 237-243
-
(2008)
Blood Cells Mol. Dis.
, vol.41
, pp. 237-243
-
-
Ogasawara, Y.1
Funakoshi, M.2
Ishii, K.3
-
34
-
-
0038359745
-
Menadione causes endothelial barrier failure by a direct effect on intracellular thiols, independent of reactive oxidant production
-
McAmis, W. C., Schaeffer, Jr, R. C., Baynes, J. W. and Wolf, M. B. (2003) Menadione causes endothelial barrier failure by a direct effect on intracellular thiols, independent of reactive oxidant production. Biochim. Biophys. Acta 1641, 43-53
-
(2003)
Biochim. Biophys. Acta
, vol.1641
, pp. 43-53
-
-
McAmis, W.C.1
Schaeffer Jr., R.C.2
Baynes, J.W.3
Wolf, M.B.4
-
35
-
-
62249096975
-
Glutathione dysregulation and the etiology and progression of human diseases
-
Ballatori, N., Krance, S. M., Notenboom, S., Shi, S., Tieu, K. and Hammond, C. L. (2009) Glutathione dysregulation and the etiology and progression of human diseases. Biol. Chem. 390, 191-214
-
(2009)
Biol. Chem.
, vol.390
, pp. 191-214
-
-
Ballatori, N.1
Krance, S.M.2
Notenboom, S.3
Shi, S.4
Tieu, K.5
Hammond, C.L.6
-
36
-
-
33646127797
-
nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis
-
Levy, M., Castillo, S. S. and Goldkorn, T. (2006) nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis. Biochem. Biophys. Res. Commun. 344, 900-905
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 900-905
-
-
Levy, M.1
Castillo, S.S.2
Goldkorn, T.3
-
37
-
-
0032079524
-
Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death
-
Liu, B., Andrieu-Abadie, N., Levade, T., Zhang, P., Obeid, L. M. and Hannun, Y. A. (1998) Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death. J. Biol. Chem. 273, 11313-11320
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11313-11320
-
-
Liu, B.1
Andrieu-Abadie, N.2
Levade, T.3
Zhang, P.4
Obeid, L.M.5
Hannun, Y.A.6
|