A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability

Journal of Biological Chemistry

Volumn 290, Issue 8, 2015, Pages 4784-4800

  Zhang, Dongyun ^a,b   Liang, Yuguang ^a   Xie, Qipeng ^b   Gao, Guangxun ^a   Wei, Jinlong ^b   Huang, Haishan ^b   Li, Jingxia ^a   Gao, Jimin ^b   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MOBILE SECURITY;

ARSENITE EXPOSURES; CELLULAR RESPONSE; INDUCED APOPTOSIS; MRNA STABILITY; MULTIFUNCTIONAL PROTEIN; NUCLEAR LOCALIZATION; POST-TRANSLATIONAL MODIFICATIONS; SUMOYLATION;

CELL DEATH;

ARSENIC TRIOXIDE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45ALPHA; LYSINE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; NUCLEOLIN; UNCLASSIFIED DRUG; ARSENOUS ACID DERIVATIVE; CELL CYCLE PROTEIN; GADD45A PROTEIN, HUMAN; GADD45A PROTEIN, MOUSE; NUCLEAR PROTEIN; PHOSPHOPROTEIN; RNA BINDING PROTEIN; SUPEROXIDE DISMUTASE; TERATOGENIC AGENT;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EMBRYO; GADD45ALPHA GENE; GENE EXPRESSION; GENETIC STABILITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN RNA BINDING; RNA METABOLISM; SUMOYLATION; 3T3 CELL LINE; ANIMAL; BIOSYNTHESIS; CELL DEATH; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; MOUSE; RNA STABILITY;

3T3 CELLS; ANIMALS; ARSENITES; CELL CYCLE PROTEINS; CELL DEATH; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; LYSINE; MICE; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; SUMOYLATION; SUPEROXIDE DISMUTASE; TERATOGENS;

EID: 84929119503     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.598219     Document Type: Article

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