The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP

Journal of Biological Chemistry

Volumn 287, Issue 42, 2012, Pages 35234-35243

  Fang, Yong ^a,b   Yu, Yonghui ^a   Hou, Qi ^c   Zheng, Xiao ^a   Zhang, Min ^a   Zhang, Dongyun ^a   Li, Jingxia ^a   Wu, Xue Ru ^a   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE COMPOUNDS; ANTI-APOPTOTIC PROTEIN; ANTICANCER ACTIVITIES; APOPTOTIC; CANCER PATIENTS; CHINESE HERBS; COLONY FORMATION; DOWN-REGULATION; GENE TRANSCRIPTIONS; HUMAN BLADDER CANCER; HUMAN CANCER CELLS; INHIBITORY EFFECT; MOLECULAR MECHANISM; OVER-EXPRESSION; PROTEIN DEGRADATION; PROTEIN EXPRESSIONS; STILBENE COMPOUNDS; TRANSACTIVATION; X-LINKED INHIBITOR OF APOPTOSIS;

CELL CULTURE; DISEASES; PATIENT TREATMENT; PLANTS (BOTANY); PROTEINS; TRANSCRIPTION;

CELL DEATH;

ANTINEOPLASTIC AGENT; ISORHAPONTIGENIN; MESSENGER RNA; STILBENE DERIVATIVE; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANCHORAGE INDEPENDENT GROWTH; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CANCER INHIBITION; CELL STRAIN HCT116; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; GENETIC TRANSCRIPTION; GNETUM; GNETUM CLEISTOSTACHYUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA STABILITY; TRANSACTIVATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GNETUM; HUMANS; NEOPLASM PROTEINS; PROTEOLYSIS; STILBENES; URINARY BLADDER NEOPLASMS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84867433216     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.389494     Document Type: Article

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