Dose-dependent effects of a soluble dietary fibre (pectin) on food intake, adiposity, gut hypertrophy and gut satiety hormone secretion in rats

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Adam, Clare L ^a   Williams, Patricia A ^a   Garden, Karen E ^a   Thomson, Lynn M ^a   Ross, Alexander W ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GASTROINTESTINAL HORMONE; GLUCAGON LIKE PEPTIDE 1; PECTIN; PEPTIDE YY;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CECUM; CONTROLLED STUDY; CRYPT CELL; DIETARY FIBER; FAT CONTENT; FAT MASS; FOOD INTAKE; HISTOLOGY; HORMONE BLOOD LEVEL; HORMONE RELEASE; HYPERTROPHY; ILEUM; INTESTINE ADAPTATION; INTESTINE HYPERTROPHY; INTESTINE VILLUS; JEJUNUM; MALE; NONHUMAN; OBESITY; ORGAN SIZE; ORGAN WEIGHT; RAT; SATIETY; WEIGHT CONTROL; WEIGHT GAIN; YOUNG ADULT; ADMINISTRATION AND DOSAGE; ANIMAL; BLOOD; BODY WEIGHT; DRUG EFFECTS; FEEDING BEHAVIOR; GASTROINTESTINAL TRACT; METABOLISM; SECRETION (PROCESS);

ANIMALIA; MALUS X DOMESTICA; RATTUS;

ADIPOSITY; ANIMALS; BODY COMPOSITION; BODY WEIGHT; DIETARY FIBER; FEEDING BEHAVIOR; GASTROINTESTINAL HORMONES; GASTROINTESTINAL TRACT; MALE; PECTINS; RATS;

EID: 84928947693     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115438     Document Type: Article

References (42)

1. Clark MJ, Slavin JL (2013) The effect of fiber on satiety and food intake: a systematic review. J Am Coll Nutr 32: 200-211. doi: 10.1080/07315724.2013.791194 PMID: 23885994
2. Adam CL, Williams PA, Dalby MJ, Garden K, Thomson LM, et al. (2014) Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats. Nutr Metab 11: 36. doi: 10.1186/1743-7075-11-36
3. Wikiera A, Irla M, Mika M (2014) Health-promoting properties of pectin. Postepy Hig Med Dosw (Online) 68: 590-596. doi: 10.5604/17322693.1102342
4. Institute of Medicine, National Academy of Sciences (2005) Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. National Academies Press, Washington DC.
5. Turner ND, Lipton JR (2011) Dietary fiber. Adv Nutr 2: 151-152. doi: 10.3945/an.110.000281 PMID: 22332044
6. Cani PD, Dewever C, Delzenne NM (2004) Inulin-type fructans modulate gastrointestinal peptides involved in appetite regulation (glucagon-like peptide-1 and ghrelin) in rats. Br J Nutr 92: 521-526. doi: 10.1079/BJN20041225 PMID: 15469657
7. Huang XF, Yu Y, Beck EJ, South T, Li Y, et al. (2011) Diet high in oat β-glucan activates the gut-hypothalamic (PYY3-36-NPY) axis and increases satiety in diet-induced obesity in mice. Mol Nutr Food Res 55: 118-1121. doi: 10.1002/mnfr.201100095
8. Lin N, Li Y, Tang L, Shi J, Chen Y (2013) In vivo effect of oat cereal β-glucan on metabolic indexes and satiety-related hormones in diet-induced obesity C57-Bl mice. Mol Nutr Food Res 57: 1291-1294. doi: 10.1002/mnfr.201200695 PMID: 23512521
9. Chelikani PK, Haver AC, Reidelberger RD (2006) Dose-dependent effects of peptide YY(3-36) on conditioned taste aversion in rats. Peptides 27: 3193-3201. doi: 10.1016/j.peptides.2006.08.001 PMID: 16962209
10. Nadkarni PP, Costanzo RM, Sakagami M (2011) Pulmonary delivery of peptide YY for food intake suppression and reduced body weight gain in rats. Diabetes Obes Metab 13: 408-417. doi: 10.1111/j.1463-1326.2011.01363.x PMID: 21226821
11. Gallwitz B (2012) Anorexigenic effects of GLP-1 and its analogues. Handb Exp Pharmacol 209: 185-207. doi: 10.1007/978-3-642-24716-3-8 PMID: 22249815
12. Parnell JA, Reimer RA (2012) Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp rats. Br J Nutr 107: 601-613. doi: 10.1017/S0007114511003163 PMID: 21767445
13. Pedersen C, Lefevre S, Peters V, Patterson M, Ghatei MA, et al. (2013) Gut hormone release and appetite regulation in healthy non-obese participants following oligofructose intake. A dose-escalation study. Appetite 66: 44-53.
14. Brown RC, Kelleher J, Losowsky MS (1979) The effect of pectin on the structure and function of the rat small intestine. Br J Nutr 42: 357-365. doi: 10.1079/BJN19790125 PMID: 508699
15. Goodlad RA, Ratcliffe B, Fordham JP, Wright NA (1989) Does dietary fibre stimulate epithelial cell proliferation in germ free rats? Gut 30: 820-825.
16. McCullough JS, Ratcliffe B, Mandir N, Carr KE, Goodlad RA (1998) Dietary fibre and intestinal microflora: effects on intestinal morphometry and crypt branching. Gut 42: 799-806. doi: 10.1136/gut.42.6.799
17. Holst JJ (2007) The physiology of glucagon-like peptide 1. Physiol Rev 87: 1409-1439. doi: 10.1152/physrev.00034.2006 PMID: 17928588
18. Willis HJ, Thomas W, Eldridge AL, Harkness L, Green H, et al. (2010) Increasing doses of fiber do not influence short-term satiety or food intake and are inconsistently linked to gut hormone levels. Food Nutr Res 54: 10.3402/fnr.v54i0.5135. doi: 10.3402/fnr.v54i0.5135 PMID: 20596303
19. Sengupta P (2013) The Laboratory Rat: Relating Its Age With Human's. Int J Prev Med 4: 624-630. PMID: 23930179
20. Wanders AJ, Mars M, Borgonjen-van den Berg KJ, de Graaf C, Feskens EJ (2014) Satiety and energy intake after single and repeated exposure to gel-forming dietary fiber: post-ingestive effects. Int J Obes (Lond) 38: 794-800. doi: 10.1038/ijo.2013.176
21. Verdich C, Flint A, Gutzwiller JP, Näslund E, Beglinger C, et al. (2001) A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans. J Clin Endocrinol Metab 86: 4382-4389. doi: 10.1210/jcem.86.9.7877 PMID: 11549680
22. Hansen CF, Vrang N, Sangild PT, Jelsing J (2013) Novel insight into the distribution of L-cells in the rat intestinal tract. Am J Transl Res 5: 347-358. PMID: 23634245
23. Tazoe H1, Otomo Y, Kaji I, Tanaka R, Karaki SI, et al. (2008) Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions. J Physiol Pharmacol 59 Suppl 2: 251-262.
24. Sleeth ML, Thompson EL, Ford HE, Zac-Varghese SE, Frost G (2010) Free fatty acid receptor 2 and nutrient sensing: a proposed role for fibre, fermentable carbohydrates and short-chain fatty acids in appetite regulation. Nutr Res Rev 23: 135-145. doi: 10.1017/S0954422410000089 PMID: 20482937
25. Kaji I, Karaki S, Tanaka R, Kuwahara A (2011) Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide. J Mol Histol 42: 27-38. doi: 10.1007/s10735-010-9304-4 PMID: 21113792
26. Tolhurst G, Heffron H, Lam YS, Parker HE, Habib AM, et al. (2012) Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes 61: 364-371. doi: 10.2337/db11-1019 PMID: 22190648
27. Hansen CF, Bueter M, Theis N, Lutz T, Paulsen S, et al. (2013) Hypertrophy dependent doubling of L-cells in Roux-en-Y gastric bypass operated rats. PLoS One 8:e65696. doi: 10.1371/journal.pone.0065696 PMID: 23776529
28. Chun W, Bamba T, Hosoda S (1989) Effect of pectin, a soluble dietary fiber, on functional and morphological parameters of the small intestine in rats. Digestion 42: 22-29. doi: 10.1159/000199821 PMID: 2545493
29. Knapp BK, Bauer LL, Swanson KS, Tappenden KA, Fahey GC Jr, et al. (2013) Soluble fiber dextrin and soluble corn fiber supplementation modify indices of health in cecum and colon of Sprague-Dawley rats. Nutrients 5: 396-410. doi: 10.3390/nu5020396 PMID: 23381099
30. Licht TR, Hansen M, Bergström A, Poulsen M, Krath BN, et al. (2010) Effects of apples and specific apple components on the cecal environment of conventional rats: role of apple pectin. BMC Microbiol 10:13. doi: 10.1186/1471-2180-10-13 PMID: 20089145
31. Sakata T, von Engelhardt W (1983) Stimulatory effect of short chain fatty acids on the epithelial cell proliferation in rat large intestine. Comp Biochem Physiol A Comp Physiol 74: 459-462.
32. Kripke SA, Fox AD, Berman JM, Settle RG, Rombeau JL (1989) Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acids. JPEN J Parenter Enteral Nutr 13: 109-116. doi: 10.1177/0148607189013002109 PMID: 2496241
33. Ichikawa H, Sakata T (1997) Effect of L-lactic acid, short-chain fatty acids, and pH in cecal infusate on morphometric and cell kinetic parameters of rat cecum. Dig Dis Sci 42: 1598-1610. doi: 10.1023/A:1018884625737 PMID: 9286223
34. Borg CM, le Roux CW, Ghatei MA, Bloom SR, Patel AG (2007) Biliopancreatic diversion in rats is associated with intestinal hypertrophy and with increased GLP-1, GLP-2 and PYY levels. Obes Surg 17: 1193-1198. doi: 10.1007/s11695-007-9211-2 PMID: 18074494
35. Drucker DJ1, Erlich P, Asa SL, Brubaker PL (1996) Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proc Natl Acad Sci USA 93: 7911-7916. doi: 10.1073/pnas.93.15.7911 PMID: 8755576
36. Thulesen J (2004) Glucagon-like peptide 2 (GLP-2), an intestinotrophic mediator. Curr Protein Pept Sci 5: 51-65. doi: 10.2174/1389203043486946 PMID: 14965320
37. Orskov C, Holst JJ, Knuhtsen S, Baldissera FG, Poulsen SS, et al. (1986) Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas. Endocrinology 119: 1467-1475. doi: 10.1210/endo-119-4-1467 PMID: 3530719
38. Ghatei MA1, Goodlad RA, Taheri S, Mandir N, Brynes AE, et al. (2001) Proglucagon-derived peptides in intestinal epithelial proliferation: glucagon-like peptide-2 is a major mediator of intestinal epithelial proliferation in rats. Dig Dis Sci 46: 1255-1263. doi: 10.1023/A:1010615429639 PMID: 11414302
39. Allen JM, Fitzpatrick ML, Yeats JC, Darcy K, Adrian TE, et al. (1984) Effects of peptide YY and neuropeptide Y on gastric emptying in man. Digestion 30: 255-262. doi: 10.1159/000199117 PMID: 6548978
40. Maljaars PW, Peters HP, Mela DJ, Masclee AA (2008) Ileal brake: a sensible food target for appetite control. A review. Physiol Behav 95: 271-281. doi: 10.1016/j.physbeh.2008.07.018
41. Mudgil D, Barak S (2013) Composition, properties and health benefits of indigestible carbohydrate polymers as dietary fiber: A review. Int J Biol Macromol 61: 1-6. doi: 10.1016/j.ijbiomac.2013.06.044 PMID: 23831534
42. le Roux CW, Borg C, Wallis K, Vincent RP, Bueter M, et al. (2010) Gut hypertrophy after gastric bypass is associated with increased glucagon-like peptide 2 and intestinal crypt cell proliferation. Ann Surg 252: 50-56. doi: 10.1097/SLA.0b013e3181d3d21f PMID: 20562614