Glucagon-like peptide 2 (GLP-2), an intestinotrophic mediator

Current Protein and Peptide Science

Volumn 5, Issue 1, 2004, Pages 51-65

  Thulesen, J ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Dipeptidyl peptidase IV; Glucagon like peptide 2; Growth factors; Intestinal growth; Proglucagon derived peptides

Indexed keywords

AMINO ACID; AMINOPEPTIDASE; GASTROINTESTINAL POLYPEPTIDE; GLUCAGON; GLUCAGON LIKE PEPTIDE 2; HORMONE RECEPTOR; INTESTINE ENZYME;

DISEASE MODEL; DRUG DEGRADATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; ENDOCRINE FUNCTION; ENTEROPATHY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HORMONE RELEASE; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER; INTESTINE FUNCTION; INTESTINE MUCOSA; INTESTINE SURGERY; INTESTINE TRANSIT TIME; L CELL; NONHUMAN; NUTRIENT; PARACRINE SIGNALING; PEPTIDE SYNTHESIS; PROTEIN LOCALIZATION; RAT; REVIEW; SEQUENCE HOMOLOGY; SHORT BOWEL SYNDROME; TISSUE GROWTH;

AMINO ACID SEQUENCE; ANIMALS; GASTROINTESTINAL HORMONES; GLICENTIN; GLUCAGON; GLUCAGON-LIKE PEPTIDE 2; GLUCAGON-LIKE PEPTIDES; HUMANS; INTESTINES; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN PRECURSORS; RATS; RECEPTORS, GLUCAGON;

ANIMALIA;

EID: 1442351173     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389203043486946     Document Type: Review

References (184)

1. Sutherland, E.W. and Duve, C. (1948) J. Biol. Chem., 175, 663-674.
2. Orci, L., Pictet, R., Forssmann, W.G., Renold, A.E. and Rouiller, C. (1968) Diabetologia, 4, 56-67.
3. Polak, J.M., Bloom, S., Coulling, I. and Pearse, A.G. (1971) Gut, 12, 311-318.
4. Knudsen, J.B., Holst, J.J., Asnaes, S. and Johansen, A. (1975) Acta Pathol. Microbiol. Scand, 83, 741-743.
5. Tanaka, R., Matsuyama, T., Shima, K., Sawazaki, N., Tarui, S. and Kumahara, Y. (1979) Endocrinol. Jpn., 26, 59-63.
6. Gleeson, M.H., Bloom, S.R., Polak, J.M., Henry, K. and Dowling, R.H. (1970) Gut, 11, 1050.
7. Bloom, S.R. (1972) Gut, 13, 520-523.
8. Stevens, F.M., Flanagan, R.W., O'Gorman, D. and Buchanan, K.D. (1984) Gut, 25, 784-791.
9. Byrne, M.M., McGregor, G.P., Barth, P., Rothmund, M., Goke, B. and Arnold, R. (2001) Digestion, 63, 61-68.
10. Bloom, S.R. and Polak, J.M. (1982) Scand. J. Gastroenterol. Suppl., 74, 93-103.
11. Bloom, S.R. (1979) Eur. J. Clin. Invest., 9, 111-113.
12. Holst, J.J., Sorensen, T.I., Andersen, A.N., Stadil, F., Andersen, B., Lauritsen, K.B. and Klein, H.C. (1979) Scand. J. Gastroenterol., 14, 205-207.
13. Jacobs, L.R., Bloom, S.R. and Dowling, R.H. (1981) Life Sci., 29, 2003-2007.
14. Sagor, G.R., Al Mukhtar, M.Y., Ghatei, M.A., Wright, N.A. and Bloom, S.R. (1982) Br. J. Surg., 69, 14-18.
15. Lund, P.K., Ulshen, M.H., Rountree, D.B., Selub, S.E. and Buchan, A.M. (1990) Digestion, 46 Suppl. 2, 66-73.
16. Gregor, M., Menge, H., Stossel, R. and Riecken, E.O. (1987) Gut, 28 Suppl, 9-14.
17. Gregor, M., Stallmach, A., Menge, H. and Riecken, E.O. (1990) Digestion, 46 Suppl. 2, 59-65.
18. Bell, G.I., Sanchez-Pescador, R., Laybourn, P.J. and Najarian, R.C. (1983) Nature, 304, 368-371.
19. Bell, G.I., Santerre, R.F. and Mullenbach, G.T. (1983) Nature, 302, 716-718.
20. Holst, J.J. (1983) Gastroenterology, 84, 1602-1613.
21. Lund, P.K., Goodman, R.H. and Habener, J.F. (1981) J. Biol. Chem., 256, 6515-6518.
22. Lund, P.K., Goodman, R.H., Dee, P.C. and Habener, J.F. (1982) Proc. Natl. Acad. Sci. USA, 79, 345-349.
23. Irwin, D.M. and Wong, J. (1995) Mol. Endocrinol., 9, 267-277.
24. Mojsov, S., Heinrich, G., Wilson, I.B., Ravazzola, M., Orci, L. and Habener, J.F. (1986) J. Biol. Chem., 261, 11880-11889.
25. Dhanvantari, S., Seidah, N.G. and Brubaker, P.L. (1996) Mol. Endocrinol., 10, 342-355.
26. Holst, J.J. (1997) Annu. Rev. Physiol., 59, 257-271.
27. Nian, M., Drucker, D.J. and Irwin, D. (1999) Am. J. Physiol., 277, G829-G837.
28. Kieffer, T.J. and Habener, J.F. (1999) Endocr. Rev., 20, 876-913.
29. Holst, J.J., Bersani, M., Johnsen, A.H., Kofod, H., Hartmann, B. and Orskov, C. (1994) J. Biol. Chem., 269, 18827-18833.
30. Lee, Y.C., Asa, S.L. and Drucker, D.J. (1992) J. Biol. Chem., 267, 10705-10708.
31. Ehrlich, P., Tucker, D., Asa, S.L., Brubaker, P.L. and Drucker, D.J. (1994) Am. J. Physiol., 267, E662-E671.
32. Drucker, D.J., Erlich, P., Asa, S.L. and Brubaker, P.L. (1996) Proc. Natl. Acad. Sci. USA, 93, 7911-7916.
33. Ziegler, T.R., Estivariz, C.F., Jonas, C.R., Gu, L.H., Jones, D.P. and Leader, L.M. (1999) JPEN J. Parenter. Enteral. Nutr., 23, S174-S183.
34. Brubaker, P.L., Crivici, A., Izzo, A., Ehrlich, P., Tsai, C.H. and Drucker, D.J. (1997) Endocrinology, 138, 4837-4843.
35. Vinter-Jensen, L., Smerup, M., Kissmeyer-Nielsen, P. and Poulsen, S.S. (1995) Regul. Pept., 60, 117-124.
36. Inaba, T., Saito, H., Fukushima, R., Hashiguchi, Y., Lin, M.T., Inoue, T., Fukatsu, K., Muto, T., Takenaka, A., Takahashi, S. and Noguchi, T. (1996) JPEN J. Parenter. Enteral. Nutr., 20, 325-331.
37. Lo, H.C. and Ney, D.M. (1996) Am. J. Physiol., 271, E872-E878.
38. Peterson, C.A., Ney, D.M., Hinton, P.S. and Carey, H.V. (1996) Gastroenterology, 111, 1501-1508.
39. Chance, W.T., Sheriff, S., Foley-Nelson, T., Thomas, I. and Balasubramaniam, A. (2000) Nutr. Cancer., 37, 215-222.
40. Ghatei, M.A., Uttenthal, L.O., Bryant, M.G., Christofides, N.D., Moody, A.J. and Bloom, S.R. (1983) Endocrinology, 112, 917-923.
41. Sjolund, K., Sanden, G., Hakanson, R. and Sundler, F. (1983) Gastroenterology, 85, 1120-1130.
42. Evans, G.S. and Potten, C.S. (1988) Virchows Arch B Cell Pathol. Incl. Mol. Pathol., 56, 191-199.
43. Greeley, G.H., Jr., Jeng, Y.J., Gomez, G., Hashimoto, T., Hill, F.L., Kern, K., Kurosky, T., Chuo, H.F. and Thompson, J.C. (1989) Endocrinology, 124, 1438-1443.
44. Nilsson, O., Bilchik, A.J., Goldenring, J.R., Ballantyne, G.H., Adrian, T.E. and Modlin, I.M. (1991) Endocrinology, 129, 139-148.
45. Eissele, R., Goke, R., Weichardt, U., Fehmann, H.C., Arnold, R. and Goke, B. (1994) Cell. Tissue Res., 276, 571-579.
46. Varndell, I.M., Bishop, A.E., Sikri, K.L., Uttenthal, L.O., Bloom, S.R. and Polak, J.M. (1985) J. Histochem. Cytochem., 33, 1080-1086.
47. Capello C., Finzi, G., Cornaggia, M., Usellini, L., Luinetti, O., Buffa, R. and Solcia, E. (1990) in The Stomach as an Endocrine Organ (Hakanson, R., Sundler, F., eds). Pp 27-51. Elsevier, Amsterdam.
48. Larsen, P.J., Tang-Christensen, M., Holst, J.J. and Orskov, C. (1997) Neuroscience, 77, 257-270.
49. Tang-Christensen, M., Larsen, P.J., Thulesen, J., Romer, J. and Vrang, N. (2000) Nat. Med., 6, 802-807.
50. Munroe, D.G., Gupta, A.K., Kooshesh, F., Vyas, T.B., Rizkalla, G., Wang, H., Demchyshyn, L., Yang, Z.J., Kamboj, R.K., Chen, H., McCallum, K., Sumner-Smith, M., Drucker, D.J. and Crivici, A. (1999) Proc. Natl. Acad. Sci. USA, 96, 1569-1573.
51. Thulesen, J., Hartmann, B., Orskov, C., Jeppesen, P.B., Holst, J.J. and Poulsen, S.S. (2000) Peptides, 21, 1511-1517.
52. Yusta, B., Boushey, R.P. and Drucker, D.J. (2000) J. Biol. Chem., 275, 35345-35352.
53. Bjerknes, M. and Cheng, H. (2001) Proc. Natl. Acad. Sci. USA, 98, 12497-12502.
54. Lovshin, J., Yusta, B., Iliopoulos, I., Migirdicyan, A., Dableh, L., Brubaker, P.L. and Drucker, D.J. (2000) Endocrinology, 141, 4194-4201.
55. Petersen, Y.M., Burrin, D.G. and Sangild, P.T. (2001) Am. J. Physiol., 281, R1986-R1993.
56. Hartmann, B., Johnsen, A.H., Orskov, C., Adelhorst, K., Thim, L. and Holst, J.J. (2000) Peptides, 21, 73-80.
57. Drucker, D.J., Shi, Q., Crivici, A., Sumner-Smith, M., Tavares, W., Hill, M., DeForest, L., Cooper, S. and Brubaker, P.L. (1997) Nat. Biotechnol., 15, 673-677.
58. Tavares, W., Drucker, D.J. and Brubaker, P.L. (2000) Am. J. Physiol. Endocrinol. Metab., 278, E134-E139.
59. Hartmann, B., Thulesen, J., Kissow, H., Thulesen, S., Orskov, C., Ropke, C., Poulsen, S.S. and Holst, J.J. (2001) Endocrinology, 141, 4013-4020.
60. Walter, R., Simmons, W.H. and Yoshimoto, T. (1980) Mol. Cell. Biochem., 30, 111-127.
61. Mentlein R (1999) Regul. Pept., 85, 9-24.
62. Watanabe, Y., Kojima, T. and Fujimoto, Y. (1987) Experientia, 43, 400-401.
63. Mentlein, R. (1988) FEBS Lett., 234, 251-256.
64. Hartel, S., Gossrau, R., Hanski, C. and Reutter, W. (1988) Histochemistry, 89, 151-161.
65. Mentlein, R., Gallwitz, B. and Schmidt, W.E. (1993) Eur. J. Biochem., 214, 829-835.
66. Hansen, L., Deacon, C.F., Orskov, C. and Holst, J.J. (1999) Endocrinology, 140, 5356-5363.
67. Gallwitz, B., Schmidt, W.E., Conlon, J.M. and Creutzfeldt, W. (1990) J. Mol. Endocrinol., 5, 33-39.
68. Adelhorst, K., Hedegaard, B.B., Knudsen, L.B. and Kirk, O. (1994) J. Biol. Chem., 269, 6275-6278.
69. Thulesen, J., Knudsen, L.B., Hartmann, B., Hastrup, S., Kissow, H., Jeppesen, P.B., Orskov, C., Holst, J.J. and Poulsen, S.S. (2002) Regul. Pept., 103, 9-15.
70. Gault, V.A., Parker, J.C., Harriott, P., Flatt, P.R. ad O'Harte, F.P.M. (2002) J. Endocrinol., 175, 525-533.
71. Knudsen, L.B. and Pridal, L. (1996) Eur. J. Pharmacol., 318, 429-435.
72. Wettergren, A., Wøjdemann, M. and Holst, J.J. (1998) Peptides, 19, 877-882.
73. Hartmann, B., Harr, M.B., Jeppesen, P.B., Wojdemann, M., Deacon, C.F., Mortensen, P.B. and Holst, J.J. (2000) J. Clin. Endocrinol. Metab., 85, 2884-2888.
74. Drucker, D.J., DeForest, L. and Brubaker, P.L. (1997) Am. J. Physiol., 273, G1252-G1262.
75. Deacon, C.F., Knudsen, L.B., Madsen, K., Wiberg, F.C., Jacobsen, O. and Holst, J.J. (1998) Diabetologia, 41, 271-278.
76. Siegel, E.G., Gallwitz, B., Scharf, G., Mentlein, R., Morys-Wortmann, C., Folsch, U.R., Schrezenmeir, J., Drescher, K. and Schmidt, W.E. (1999) Regul. Pept., 79, 93-102.
77. Gault, V.A., O'Harte, F.P., Harriott, P. and Flatt, P. (2003) Metabolism, 52, 679-687.
78. Chance, W.T., Foley-Nelson, T., Thomas, I. and Balasubramaniam, A. (1997) Am. J. Physiol, 273, G559-G563.
79. Tsai, C.H., Hill, M., Asa, S.L., Brubaker, P.L. and Drucker, D.J. (1997) Am. J. Physiol., 273, E77-E84.
80. Benjamin, M.A., McKay, D.M., Yang, P.C., Cameron, H. and Perdue, M.H. (2000) Gut, 47, 112-119.
81. Kitchen, P.A., Fitzgerald, A.J., Goodlad, R.A., Barley, N.F., Ghatei, M.A., Legon, S., Bloom, S.R., Price, A., Walters, J.R. and Forbes, A. (2000) Am. J. Physiol., 278, G425-G428.
82. Ruiz-Grande, C., Pintado, J., Alarcon, C., Castilla, C., Valverde, I. and Lopez-Novoa, J.M. (1990) Can. J. Physiol. Pharmacol., 68, 1568-1573.
83. Tsai, C.H., Hill, M. and Drucker, D.J. (1997) Am. J. Physiol., 272, G662-G668.
84. Brubaker, P.L., Izzo, A., Hill, M. and Drucker, D.J. (1997) Am. J. Physiol., 272, E1050-E1058.
85. Cheeseman, C.I. and Tsang, R. (1996) Am. J. Physiol., 271, G477-G482.
86. Cheeseman, C.I. (1997) Am. J. Physiol., 273, R1965-R1971.
87. Cheeseman, C.I. and O'Neill, D. (1998) Exp. Physiol., 83, 605-616.
88. Kato, Y., Yu, D. and Schwartz, M.Z. (1999) J. Pediatr. Surg., 34, 18-20.
89. Read, N.W., McFarlane, A., Kinsman, R.I., Bates, T.E., Blackhall, N.W., Farrar, G.B., Hall, J.C., Moss, G., Morris, A.P. and O'Neill, B. (1984) Gastroenterology, 86, 274-280.
90. Wojdemann, M., Wettergren, A., Hartmann, B., Hilsted, L. and Holst, J.J. (1999) J. Clin. Endocrinol. Metab., 84, 2513-2517.
91. Wojdemann, M., Wettergren, A., Hartmann, B. and Holst, J.J. (1998) Scand. J. Gastroenterol., 33, 828-832.
92. Drucker, D.J., Boushey, R.P., Wang, F., Hill, M.E., Brubaker, P.L. and Yusta, B. (1999) JPEN J. Parenter. Enteral. Nutr., 23, S98-100.
93. Goodlad, R.A. and Wright, N.A. (1987) Experientia, 43, 780-784.
94. Jervis, E.L. and Levin, R.J. (1966) Nature, 210, 391-393.
95. Schedl, H.P. and Wilson, H.D. (1971) J. Exp. Zool., 176, 487-495.
96. Pillion, D.J., Jenkins, R.L., Atchison, J.A., Stockard, C.R., Clements, R.S., Jr. and Grizzle, W.E. (1988) Am. J. Physiol., 254, E749-E755.
97. Brubaker, P.L., So, D.C. and Drucker, D.J. (1989) Endocrinology, 124, 3003-3009.
98. Fischer, K.D, Dhanvantari, S., Drucker, D.J. and Brubaker, P.L. (1997) Am. J. Physiol., 273, E815-E820.
99. Thulesen, J., Orskov, C., Holst, J.J. and Poulsen, S.S. (1997) Endocrinology, 138, 62-68.
100. Matsuyama, T., Hoffman, W.H., Dunbar, J.C., Foa, N.L. and Foa, P.P. (1975) Horm. Metab. Res., 7, 452-456.
101. Wider, M.D., Matsuyama, T., Dunbar, J.C. and Foa, P.P. (1976) Metabolism, 25, 1487-1489.
102. Roberge, J.N. and Brubaker, P.L. (1991) Endocrinology, 128, 3169-3174.
103. Conlon, J.M., Deacon, C.F., Bailey, C.J. and Flatt, P.R. (1986) Diabetologia, 29, 334-338.
104. Thulesen, J., Hartmann, B., Nielsen, C., Holst, J.J. and Poulsen, S.S. (1999) Gut, 45, 672-678.
105. Reimer, R.A. and McBurney, M.I. (1996) Endocrinology, 137, 3948-3956.
106. Gee, J.M., Lee-Finglas, W., Wortley, G.W. and Johnson, I.T. (1996) J. Nutr., 126, 373-379.
107. Hartmann, B, Thulesen, J, Hare, K. J., Kissow, H, Orskov, C, Poulsen, S. S., and Holst, J. J. (2002) Regul. Pept., 105, 173-179.
108. Buts, J.P., Morin, C.L. and Ling, V. (1979) Clin. Invest. Med., 2, 59-66.
109. Weser, E., Vandeventer, A. and Tawil, T. (1982) Scand. J. Gastroenterol. Suppl., 74, 105-113.
110. Tamada, H., Nezu, R., Imamura, I., Matsuo, Y., Takagi, Y., Kamata, S. and Okada, A. (1992) JPEN J. Parenter. Enteral. Nutr., 16, 110-116.
111. Ziegler, T.R., Almahfouz, A., Pedrini, M.T. and Smith, R.J. (1995) Endocrinology, 136, 5148-5154.
112. Orskov, C. and Holst, J.J. (1987) Scand. J. Clin. Lab. Invest., 47, 165-174.
113. Hoyt, E.C., Lund, P.K., Winesett, D.E., Fuller, C.R., Ghatei, M.A., Bloom, S.R. and Ulshen, M.H. (1996) Diabetes, 45, 434-439.
114. Jeppesen, P.B., Hartmann, B., Hansen, B.S., Thulesen, J., Holst, J.J. and Mortensen, P.B. (1999) Gut, 45, 559-563.
115. Xiao, Q., Boushey, R.P., Drucker, D.J. and Brubaker, P.L. (1999) Gastroenterology, 117, 99-105.
116. Rubin, D.C. (1999) Gastroenterology, 117, 261-263.
117. Burrin, D.G., Stoll, B., Jiang, R., Petersen, Y., Elnif, J., Buddington, R.K., Schmidt, M., Holst, J.J., Hartmann, B. and Sangild, P.T. (2000) Am. J. Physiol., 279, G1249-G1256.
118. van Goudoever, J.B., Stoll, B., Hartmann, B., Holst, J.J., Reeds, P.J. and Burrin, D.G. (2001) J. Nutr., 131, 729-732.
119. Roberge, J.N. and Brubaker, P.L. (1993) Endocrinology, 133, 233-240.
120. Rocca, A.S. and Brubaker, P.L. (1995) Endocrinology, 136, 5593-5599.
121. Thomsen, C., Rasmussen, O., Lousen, T., Holst, J.J., Fenselau, S., Schrezenmeir, J. and Hermansen, K. (1999) Am. J. Clin. Nutr., 69, 1135-1143.
122. Rocca, A.S., LaGreca, J., Kalitsky, J. and Brubaker, P.L. (2001) Endocrinology, 142, 1148-1155.
123. Cordier-Bussat, M., Bernard, C., Levenez, F., Klages, N., Laser-Ritz, B., Philippe, J., Chayvialle, J.A. and Cuber, J.C. (1998) Diabetes, 47, 1038-1045.
124. Goodlad, R.A. and Wright, N.A. (1983) Br. J. Nutr., 50, 91-98.
125. Jacobs, L.R. (1983) Am. J. Clin. Nutr., 37, 954-960.
126. Sakata, T. and Yajima, T. (1984) Q. J. Exp. Physiol., 69, 639-648.
127. Sakata, T. (1987) Br. J. Nutr., 58, 95-103.
128. Goodlad, R.A., Ratcliffe, B., Fordham, J.P. and Wright, N.A. (1989) Gut, 30, 820-825.
129. Goodlad, R.A., Ratcliffe, B., Lee, C.Y. and Wright, N.A. (1995) Eur. J. Clin. Nutr., 49 Suppl 3, S178-S181.
130. Ropert, A., Cherbut, C., Roze, C., Le Quellec, A., Holst, J.J., Fu-Cheng, X., Bruley, D.V. and Galmiche, J.P. (1996) Gastroenterology, 111, 289-296.
131. Goodlad, R.A., Lenton, W., Ghatei, M.A., Adrian, T.E., Bloom, S.R. and Wright, N.A. (1987) Gut, 28 Suppl, 221-226.
132. Sakata, T. (1989) Scand. J. Gastroenterol., 24, 886-890.
133. Tappenden, K.A., Thomson, A.B., Wild, G.E. and McBurney, M.I. (1996) JPEN J. Parenter. Enteral. Nutr., 20, 357-362.
134. Dumoulin, V., Moro, F., Barcelo, A., Dakka, T. and Cuber, J.C. (1998) Endocrinology, 139, 3780-3786.
135. Hanauer, S.B. (1996) N. Engl. J. Med., 334, 841-848.
136. Plaisancie, P., Dumoulin, V., Chayvialle, J.A. and Cuber, J.C. (1995) J. Endocrinol., 145, 521-526.
137. D'Alessio, D., Thirlby, R., Laschansky, E., Zebroski, H. and Ensinck, J. (1993) Digestion, 54, 377-379.
138. Brubaker, P.L. (1991) Endocrinology, 128, 3175-3182.
139. Knapper, J.M., Heath, A., Fletcher, J.M., Morgan, L.M. and Marks, V. (1995) Comp. Biochem. Physiol. C. Pharmacol. Toxicol. Endocrinol., 111, 445-450.
140. Roberge, J.N., Gronau, K.A. and Brubaker, P.L. (1996) Endocrinology, 137, 2383-2388.
141. Rocca, A.S. and Brubaker, P.L. (1999) Endocrinology, 140, 1687-1694.
142. Berthoud, H.R., Kressel, M., Raybould, H.E. and Neuhuber, W.L. (1995) Anat. Embryol. (Berl), 191, 203-212.
143. Nauck, M., Heimesaat, M.M., Ørskov, C. and Holst, J.J. (1994) J. Clin. Invest., 91, 301-307.
144. Buchman, A.L., Moukarzel, A.A., Bhuta, S., Belle, M., Ament, M.E., Eckhert, C.D., Hollander, D., Gornbein, J., Kopple, J.D. and Vijayaroghavan, S.R. (1995) JPEN J. Parenter. Enteral. Nutr., 19, 453-460.
145. Kouris, G.J., Liu, Q., Rossi, H., Djuricin, G., Gattuso, P., Nathan, C., Weinstein, R.A. and Prinz, R.A. (2001) Am. J. Surg., 181, 571-575.
146. Boushey, R.P., Yusta, B. and Drucker, D.J. (2001) Cancer Res., 61, 687-693.
147. Scott, R.B., Kirk, D., MacNaughton, W.K. and Meddings, J.B. (1998) Am. J. Physiol., 275, G911-G921.
148. Drucker, D.J., Yusta, B., Boushey, R.P., DeForest, L. and Brubaker, P.L. (1999) Am. J. Physiol., 276, G79-G91.
149. Alavi, K., Schwartz, M.Z., Palazzo, J.P. and Prasad, R.: (2000) J. Pediatr. Surg., 35, 47-851.
150. Schmidt, P.T., Hartmann, B., Bregenholt, S., Holst, J.J. and Claesson, M.H. (2000) Scand. J. Gastroenterol., 35, 522-527.
151. Dowling, R.H. and Booth, C.C. (1966) Lancet, 2, 146-147.
152. Dowling, R.H. and Booth, C.C. (1967) Clin. Sci., 32, 139-149.
153. Weser, E. and Hernandez, M.H. (1971) Gastroenterology, 60, 69-75.
154. Taylor, R.G., Verity, K. and Fuller, P.J. (1990) Gastroenterology, 99, 724-729.
155. Fuller, P.J., Beveridge, D.J. and Taylor, R.G. (1993) Gastroenterology, 104, 459-466.
156. Vanderhoof, J.A., Park, J.H., Herrington, M.K. and Adrian, T.E. (1994) Gastroenterology, 106, 94-99.
157. Koopmans, H.S., Sclafani, A., Fichtner, C., and Aravich, P.F. (1982) Am. J. Clin. Nutr., 35, 284-293.
158. Thulesen, J., Hartmann, B., Kissow, H., Jeppesen, P.B., Orskov, C., Holst, J.J. and Poulsen, S.S. (2001) Dig. Dis. Sci., 46, 379-388.
159. Nygaard, K. (1967) Acta Chir. Scand., 133, 407-416.
160. Jeppesen, P.B., Hartmann, B., Thulesen, J., Hansen, B.S., Holst, J.J., Poulsen, S.S. and Mortensen, P.B. (2000) Gut, 47, 370-376.
161. Nightingale, J.M., Kamm, M.A., van, D.S., Jr., Ghatei, M.A., Bloom, S.R., Lennard-Jones, J.E. (1996) Gut, 39, 267-272.
162. Howard, L., Ament, M., Fleming, C.R., Shike, M. and Steiger, E. (1995) Gastroenterology, 109, 355-365.
163. Jeppesen, P.B., Hartmann, B., Thulesen, J., Graff, J., Lohmann, J., Hansen, B.S., Tofteng, F., Poulsen, S.S., Madsen, J.L., Holst, J.J. and Mortensen, P.B. (2001) Gastroenterology, 120, 806-815.
164. Warner, B.W. (2001) Gastroenterology, 120, 1041-1043.
165. Meddings, J.B. (1997) Aliment. Pharmacol. Ther., 11 Suppl 3, 47-53.
166. DaCambra, M.P., Yusta, B., Sumner-Smith, M., Crivici, A., Drucker, D.J. and Brubaker, P.L. (2000) Biochemistry, 39, 8888-8894.
167. Xiao, Q., Boushey, R.P., Cino, M., Drucker, D.J. and Brubaker, P.L. (2000) Am. J. Physiol., 278, R1057-R1063.
168. Hildebrandt, M., Rose, M., Rüter, J., Salama, A., Mönnikes, H. and Klapp, B.F. (2001) Scand. J. Gastroenterol., 36, 1067-1072.
169. Pederson, R.A., White, H.A., Schlenzig, D., Pauly, R.P., McIntosh, C.H. and Demuth, H.U. (1998) Diabetes, 47, 1253-1258.
170. Holst, J.J. and Deacon, C.F. (1998) Diabetes, 47, 1663-1670.
171. Balkan, B., Kwasnik, L., Miserendino, R., Holst, J.J. and Li, X. (1999) Diabetologia, 42, 1324-1331.
172. Ahren, B., Holst, J.J., Martensson, H. and Balkan, B. (2000) Eur. J. Pharmacol., 404, 239-245.
173. Deacon, C.F., Wamberg, S., Bie,P., Hughes, T.E. and Holst, J.J. (2002) J. Endocrinol., 172, 355-362.
174. Oscarson, J.E.A., Herman, F.V., Ross, J.S. and Malt, R.A. (1979) Annals of Surgery, 189, 503-508.
175. Harte, P.J., Steele, G., Jr., Rayner, A.A., Munroe, A.E., King,V.P. and Wilson, R.E. (1981) J. Surg. Oncol., 18, 87-93.
176. Bristol, J.B., Ghatei, M.A., Smith, J.H., Bloom, S.R. and Williamson, R.C. (1987) Gastroenterology, 92, 617-624.
177. Savage, A.P., Matthews, J.L., Ghatei, M.A., Cooke, T. and Bloom, S.R. (1987) Gut, 28, 33-39.
178. Scolapio, J.S. (1999) JPEN J. Parenter. Enteral. Nutr., 23, 309-312.
179. Szkudlarek, J., Jeppesen, P.B. and Mortensen, P.B. (2000) Gut, 47, 199-205.
180. Prasad, R., Alavi, K. and Schwartz, M.Z. (2000) J. Pediatr. Surg., 35, 1537-1539.
181. Rombeau, J.L. (1990) JPEN J. Parenter. Enteral. Nutr., 14, 100S-105S.
182. Kripke, S.A., De Paula, J.A., Berman, J.M., Fox, A.D., Rombeau, J.L. and Settle, R.G. (1991) Am. J. Clin. Nutr., 53, 954-962.
183. Alison, M.R. and Sarraf, C.E. (1994) Cell Biol. Int., 18, 1-10.
184. LeLeiko, N.S. and Walsh, M.J. (1996) Pediatr. Clin. North. Am., 43, 451-470.