메뉴 건너뛰기




Volumn 7, Issue 2, 2015, Pages 283-300

Oxidative stress and DNA methylation regulation in the metabolic syndrome

Author keywords

antioxidant defense; DNA methylation; fetal programming; inflammation; metabolic syndrome; nutrition; oxidative stress

Indexed keywords

DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA METHYLATION; DNA MODIFICATION; ENVIRONMENTAL FACTOR; GENOME IMPRINTING; HUMAN; HYPERTENSION; METABOLIC SYNDROME X; NONHUMAN; NUTRITION; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; TISSUE SPECIFICITY; DIABETES MELLITUS, TYPE 2; ENZYMOLOGY; GENETIC EPIGENESIS; GENETICS; METABOLISM;

EID: 84928896809     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.14.84     Document Type: Review
Times cited : (76)

References (151)
  • 1
    • 0023279926 scopus 로고
    • The inheritance of epigenetic defects
    • Holliday R. The inheritance of epigenetic defects. Science 238(4824), 163-170 (1987).
    • (1987) Science , vol.238 , Issue.4824 , pp. 163-170
    • Holliday, R.1
  • 2
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev. 16(1), 6-21 (2002).
    • (2002) Genes Dev , vol.16 , Issue.1 , pp. 6-21
    • Bird, A.1
  • 3
    • 0020489781 scopus 로고
    • Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells
    • Ehrlich M, Gama-Sosa MA, Huang LH et al. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res. 10(8), 2709-2721 (1982).
    • (1982) Nucleic Acids Res , vol.10 , Issue.8 , pp. 2709-2721
    • Ehrlich, M.1    Gama-Sosa, M.A.2    Huang, L.H.3
  • 4
    • 0026742792 scopus 로고
    • CpG islands as gene markers in the human genome
    • Larsen F, Gundersen G, Lopez R, Prydz H. CpG islands as gene markers in the human genome. Genomics 13(4), 1095-1107 (1992).
    • (1992) Genomics , vol.13 , Issue.4 , pp. 1095-1107
    • Larsen, F.1    Gundersen, G.2    Lopez, R.3    Prydz, H.4
  • 5
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science 293(5532), 1068-1070 (2001).
    • (2001) Science , vol.293 , Issue.5532 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 6
    • 44049120882 scopus 로고
    • CpG islands in mammalian gene promoters are inherently resistant to de novo methylation
    • Bestor TH, Gundersen G, Kolsto AB, Prydz H. CpG islands in mammalian gene promoters are inherently resistant to de novo methylation. Genet. Anal. Tech. Appl. 9(2), 48-53 (1992).
    • (1992) Genet. Anal. Tech. Appl , vol.9 , Issue.2 , pp. 48-53
    • Bestor, T.H.1    Gundersen, G.2    Kolsto, A.B.3    Prydz, H.4
  • 7
    • 0032722062 scopus 로고    scopus 로고
    • Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation
    • Pradhan S, Bacolla A, Wells RD, Roberts RJ. Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J. Biol. Chem. 274(46), 33002-33010 (1999).
    • (1999) J. Biol. Chem , vol.274 , Issue.46 , pp. 33002-33010
    • Pradhan, S.1    Bacolla, A.2    Wells, R.D.3    Roberts, R.J.4
  • 8
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature 366(6453), 362-365 (1993).
    • (1993) Nature , vol.366 , Issue.6453 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 9
    • 0028786951 scopus 로고
    • Loss of methylation activates Xist in somatic but not in embryonic cells
    • Beard C, Li E, Jaenisch R. Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev. 9(19), 2325-2334 (1995).
    • (1995) Genes Dev , vol.9 , Issue.19 , pp. 2325-2334
    • Beard, C.1    Li, E.2    Jaenisch, R.3
  • 10
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19(3), 219-220 (1998).
    • (1998) Nat. Genet , vol.19 , Issue.3 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 11
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3), 247-257 (1999).
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 12
    • 0033499867 scopus 로고    scopus 로고
    • In vivo activity of murine de novo methyltransferases Dnmt3a and Dnmt3b
    • Hsieh CL. In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b. Mol. Cell Biol. 19(12), 8211-8218 (1999).
    • (1999) Mol. Cell Biol , vol.19 , Issue.12 , pp. 8211-8218
    • Hsieh, C.L.1
  • 13
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor TH. The DNA methyltransferases of mammals. Hum. Mol. Genet. 9(16), 2395-2402 (2000).
    • (2000) Hum. Mol. Genet , vol.9 , Issue.16 , pp. 2395-2402
    • Bestor, T.H.1
  • 15
    • 0036415141 scopus 로고    scopus 로고
    • Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA
    • Fatemi M, Hermann A, Gowher H, Jeltsch A. Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA. Eur. J. Biochem. 269(20), 4981-4984 (2002).
    • (2002) Eur. J. Biochem , vol.269 , Issue.20 , pp. 4981-4984
    • Fatemi, M.1    Hermann, A.2    Gowher, H.3    Jeltsch, A.4
  • 16
    • 0036683055 scopus 로고    scopus 로고
    • Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
    • Kim GD, Ni J, Kelesoglu N, Roberts RJ, Pradhan S. Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J. 21(15), 4183-4195 (2002).
    • (2002) EMBO J , vol.21 , Issue.15 , pp. 4183-4195
    • Kim, G.D.1    Ni, J.2    Kelesoglu, N.3    Roberts, R.J.4    Pradhan, S.5
  • 17
    • 0034713275 scopus 로고    scopus 로고
    • CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
    • Hark AT, Schoenherr CJ, Katz DJ, Ingram RS, Levorse JM, Tilghman SM. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature 405(6785), 486-489 (2000).
    • (2000) Nature , vol.405 , Issue.6785 , pp. 486-489
    • Hark, A.T.1    Schoenherr, C.J.2    Katz, D.J.3    Ingram, R.S.4    Levorse, J.M.5    Tilghman, S.M.6
  • 18
    • 33645999355 scopus 로고    scopus 로고
    • S-adenosylmethionine: Jack of all trades and master of everything?
    • Loenen WA. S-adenosylmethionine: jack of all trades and master of everything? Biochem. Soc. Trans. 34(Pt 2), 330-333 (2006).
    • (2006) Biochem. Soc. Trans , vol.34 , pp. 330-333
    • Loenen, W.A.1
  • 19
    • 0031792779 scopus 로고    scopus 로고
    • Identification and characterization of a family of mammalian methyl-CpG binding proteins
    • Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell Biol. 18(11), 6538-6547 (1998).
    • (1998) Mol. Cell Biol , vol.18 , Issue.11 , pp. 6538-6547
    • Hendrich, B.1    Bird, A.2
  • 20
    • 0027495467 scopus 로고
    • Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
    • Nan X, Meehan RR, Bird A. Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2. Nucleic Acids Res. 21(21), 4886-4892 (1993).
    • (1993) Nucleic Acids Res , vol.21 , Issue.21 , pp. 4886-4892
    • Nan, X.1    Meehan, R.R.2    Bird, A.3
  • 21
    • 0026583975 scopus 로고
    • Repression of genes by DNA methylation depends on CpG density and promoter strength: Evidence for involvement of a methyl-CpG binding protein
    • Boyes J, Bird A. Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein. EMBO J. 11(1), 327-333 (1992).
    • (1992) EMBO J , vol.11 , Issue.1 , pp. 327-333
    • Boyes, J.1    Bird, A.2
  • 22
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • Hsieh CL. Dependence of transcriptional repression on CpG methylation density. Mol. Cell Biol. 14(8), 5487-5494 (1994).
    • (1994) Mol. Cell Biol , vol.14 , Issue.8 , pp. 5487-5494
    • Hsieh, C.L.1
  • 23
    • 0031104930 scopus 로고    scopus 로고
    • DNA methylation directs a time-dependent repression of transcription initiation
    • Kass SU, Landsberger N, Wolffe AP. DNA methylation directs a time-dependent repression of transcription initiation. Curr. Biol. 7(3), 157-165 (1997).
    • (1997) Curr. Biol , vol.7 , Issue.3 , pp. 157-165
    • Kass, S.U.1    Landsberger, N.2    Wolffe, A.P.3
  • 24
    • 0019510628 scopus 로고
    • Reactivation of an inactive human X chromosome: Evidence for X inactivation by DNA methylation
    • Mohandas T, Sparkes RS, Shapiro LJ. Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science 211(4480), 393-396 (1981).
    • (1981) Science , vol.211 , Issue.4480 , pp. 393-396
    • Mohandas, T.1    Sparkes, R.S.2    Shapiro, L.J.3
  • 25
    • 0020436347 scopus 로고
    • 5-azacytidine-induced re-expression of alleles on the inactive X chromosome in a hybrid mouse cell line
    • Graves JA. 5-azacytidine-induced re-expression of alleles on the inactive X chromosome in a hybrid mouse cell line. Exp. Cell Res. 141(1), 99-105 (1982).
    • (1982) Exp. Cell Res , vol.141 , Issue.1 , pp. 99-105
    • Graves, J.A.1
  • 27
    • 0001408994 scopus 로고
    • Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues
    • Jaenisch R, Schnieke A, Harbers K. Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues. Proc. Natl Acad. Sci. USA 82(5), 1451-1455 (1985).
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , Issue.5 , pp. 1451-1455
    • Jaenisch, R.1    Schnieke, A.2    Harbers, K.3
  • 28
    • 0034665756 scopus 로고    scopus 로고
    • X inactivation in the mouse embryo deficient for Dnmt1: Distinct effect of hypomethylation on imprinted and random X inactivation
    • Sado T, Fenner MH, Tan SS, Tam P, Shioda T, Li E. X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation. Dev. Biol. 225(2), 294-303 (2000).
    • (2000) Dev. Biol , vol.225 , Issue.2 , pp. 294-303
    • Sado, T.1    Fenner, M.H.2    Tan, S.S.3    Tam, P.4    Shioda, T.5    Li, E.6
  • 29
    • 67649160614 scopus 로고    scopus 로고
    • Epigenetics: Connecting environment and genotype to phenotype and disease
    • Barros SP, Offenbacher S. Epigenetics: connecting environment and genotype to phenotype and disease. J. Dent. Res. 88(5), 400-408 (2009).
    • (2009) J. Dent. Res , vol.88 , Issue.5 , pp. 400-408
    • Barros, S.P.1    Offenbacher, S.2
  • 30
    • 34848911647 scopus 로고    scopus 로고
    • DNA methylation: The nuts and bolts of repression
    • Miranda TB, Jones PA. DNA methylation: the nuts and bolts of repression. J. Cell Physiol. 213(2), 384-390 (2007).
    • (2007) J. Cell Physiol , vol.213 , Issue.2 , pp. 384-390
    • Miranda, T.B.1    Jones, P.A.2
  • 31
    • 23844547591 scopus 로고    scopus 로고
    • Epigenetic deregulation of genomic imprinting in human disorders and following assisted reproduction
    • Arnaud P, Feil R. Epigenetic deregulation of genomic imprinting in human disorders and following assisted reproduction. Birth Defects Res. C. Embryo. Today 75(2), 81-97 (2005).
    • (2005) Birth Defects Res. C. Embryo. Today , vol.75 , Issue.2 , pp. 81-97
    • Arnaud, P.1    Feil, R.2
  • 32
    • 70349999407 scopus 로고    scopus 로고
    • DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
    • Tobi EW, Lumey LH, Talens RP et al. DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum. Mol. Genet. 18(21), 4046-4053 (2009).
    • (2009) Hum. Mol. Genet , vol.18 , Issue.21 , pp. 4046-4053
    • Tobi, E.W.1    Lumey, L.H.2    Talens, R.P.3
  • 33
    • 0035704552 scopus 로고    scopus 로고
    • The thrifty phenotype hypothesis
    • Hales CN, Barker DJ. The thrifty phenotype hypothesis. Br. Med. Bull. 60, 5-20 (2001).
    • (2001) Br. Med. Bull , vol.60 , pp. 5-20
    • Hales, C.N.1    Barker, D.J.2
  • 34
    • 0032751471 scopus 로고    scopus 로고
    • Epigenetic inheritance at the agouti locus in the mouse
    • Morgan HD, Sutherland HG, Martin DI, Whitelaw E. Epigenetic inheritance at the agouti locus in the mouse. Nat. Genet. 23(3), 314-318 (1999).
    • (1999) Nat. Genet , vol.23 , Issue.3 , pp. 314-318
    • Morgan, H.D.1    Sutherland, H.G.2    Martin, D.I.3    Whitelaw, E.4
  • 35
    • 84882900279 scopus 로고    scopus 로고
    • Do maternal methyl supplements in mice affect DNA methylation of offspring?
    • Waterland RA. Do maternal methyl supplements in mice affect DNA methylation of offspring? J. Nutr. 133(1), 238 (2003).
    • (2003) J. Nutr , vol.133 , Issue.1 , pp. 238
    • Waterland, R.A.1
  • 36
    • 33646790538 scopus 로고    scopus 로고
    • Assessing the effects of high methionine intake on DNA methylation
    • Waterland RA. Assessing the effects of high methionine intake on DNA methylation. J. Nutr. 136(6 Suppl.), S1706-S1710 (2006).
    • (2006) J. Nutr , vol.136 , Issue.6 , pp. S1706-S1710
    • Waterland, R.A.1
  • 37
    • 33749026098 scopus 로고    scopus 로고
    • Maternal methyl supplements increase offspring DNA methylation at axin fused
    • Waterland RA, Dolinoy DC, Lin JR, Smith CA, Shi X, Tahiliani KG. Maternal methyl supplements increase offspring DNA methylation at axin fused. Genesis 44(9), 401-406 (2006).
    • (2006) Genesis , vol.44 , Issue.9 , pp. 401-406
    • Waterland, R.A.1    Dolinoy, D.C.2    Lin, J.R.3    Smith, C.A.4    Shi, X.5    Tahiliani, K.G.6
  • 38
    • 0036322831 scopus 로고    scopus 로고
    • Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring
    • Cooney CA, Dave AA, Wolff GL. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J. Nutr. 132(8 Suppl.), S2393-S2400 (2002).
    • (2002) J. Nutr , vol.132 , Issue.8 , pp. S2393-S2400
    • Cooney, C.A.1    Dave, A.A.2    Wolff, G.L.3
  • 39
    • 34047258298 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations
    • Burdge GC, Slater-Jefferies J, Torrens C, Phillips ES, Hanson MA, Lillycrop KA. Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br. J. Nutr. 97(3), 435-439 (2007).
    • (2007) Br. J. Nutr , vol.97 , Issue.3 , pp. 435-439
    • Burdge, G.C.1    Slater-Jefferies, J.2    Torrens, C.3    Phillips, E.S.4    Hanson, M.A.5    Lillycrop, K.A.6
  • 40
    • 20444411948 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
    • Lillycrop KA, Phillips ES, Jackson AA, Hanson MA, Burdge GC. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J. Nutr. 135(6), 1382-1386 (2005).
    • (2005) J. Nutr , vol.135 , Issue.6 , pp. 1382-1386
    • Lillycrop, K.A.1    Phillips, E.S.2    Jackson, A.A.3    Hanson, M.A.4    Burdge, G.C.5
  • 41
    • 34247514180 scopus 로고    scopus 로고
    • Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications
    • Lillycrop KA, Slater-Jefferies JL, Hanson MA, Godfrey KM, Jackson AA, Burdge GC. Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications. Br. J. Nutr. 97(6), 1064-1073 (2007).
    • (2007) Br. J. Nutr , vol.97 , Issue.6 , pp. 1064-1073
    • Lillycrop, K.A.1    Slater-Jefferies, J.L.2    Hanson, M.A.3    Godfrey, K.M.4    Jackson, A.A.5    Burdge, G.C.6
  • 42
    • 66749093541 scopus 로고    scopus 로고
    • Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition
    • Burdge GC, Lillycrop KA, Phillips ES, Slater-Jefferies JL, Jackson AA, Hanson MA. Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J. Nutr. 139(6), 1054-1060 (2009).
    • (2009) J. Nutr , vol.139 , Issue.6 , pp. 1054-1060
    • Burdge, G.C.1    Lillycrop, K.A.2    Phillips, E.S.3    Slater-Jefferies, J.L.4    Jackson, A.A.5    Hanson, M.A.6
  • 43
    • 33947517327 scopus 로고    scopus 로고
    • Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension
    • Bogdarina I, Welham S, King PJ, Burns SP, Clark AJ. Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension. Circ. Res. 100(4), 520-526 (2007).
    • (2007) Circ. Res , vol.100 , Issue.4 , pp. 520-526
    • Bogdarina, I.1    Welham, S.2    King, P.J.3    Burns, S.P.4    Clark, A.J.5
  • 44
    • 75449118269 scopus 로고    scopus 로고
    • The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction
    • Van Straten EM, Bloks VW, Huijkman NC et al. The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298(2), R275-R282 (2010).
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.298 , Issue.2 , pp. R275-R282
    • Van Straten, E.M.1    Bloks, V.W.2    Huijkman, N.C.3
  • 45
    • 37649011327 scopus 로고    scopus 로고
    • DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status
    • Sinclair KD, Allegrucci C, Singh R et al. DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proc. Natl Acad. Sci. USA 104(49), 19351-19356 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.49 , pp. 19351-19356
    • Sinclair, K.D.1    Allegrucci, C.2    Singh, R.3
  • 46
    • 33646138477 scopus 로고    scopus 로고
    • Folate supplementation during pregnancy improves offspring cardiovascular dysfunction induced by protein restriction
    • Torrens C, Brawley L, Anthony FW et al. Folate supplementation during pregnancy improves offspring cardiovascular dysfunction induced by protein restriction. Hypertension 47(5), 982-987 (2006).
    • (2006) Hypertension , vol.47 , Issue.5 , pp. 982-987
    • Torrens, C.1    Brawley, L.2    Anthony, F.W.3
  • 47
    • 70350674919 scopus 로고    scopus 로고
    • Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: An epigenetic model of obesity and the metabolic syndrome
    • Plagemann A, Harder T, Brunn M et al. Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J. Physiol. 587(Pt 20), 4963-4976 (2009).
    • (2009) J. Physiol , vol.587 , pp. 4963-4976
    • Plagemann, A.1    Harder, T.2    Brunn, M.3
  • 48
    • 0025743129 scopus 로고
    • The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight
    • Godfrey KM, Redman CW, Barker DJ, Osmond C. The effect of maternal anaemia and iron deficiency on the ratio of fetal weight to placental weight. Br. J. Obstet. Gynaecol. 98(9), 886-891 (1991).
    • (1991) Br. J. Obstet. Gynaecol , vol.98 , Issue.9 , pp. 886-891
    • Godfrey, K.M.1    Redman, C.W.2    Barker, D.J.3    Osmond, C.4
  • 49
    • 0142150023 scopus 로고    scopus 로고
    • Iron deficiency during pregnancy affects postnatal blood pressure in the rat
    • Gambling L, Dunford S, Wallace DI et al. Iron deficiency during pregnancy affects postnatal blood pressure in the rat. J. Physiol 552(Pt 2), 603-610 (2003).
    • (2003) J. Physiol , vol.552 , pp. 603-610
    • Gambling, L.1    Dunford, S.2    Wallace, D.I.3
  • 50
    • 0026316923 scopus 로고
    • Islet function in offspring of mothers on low-protein diet during gestation
    • Dahri S, Snoeck A, Reusens-Billen B, Remacle C, Hoet JJ. Islet function in offspring of mothers on low-protein diet during gestation. Diabetes 40(Suppl. 2), 115-120 (1991).
    • (1991) Diabetes , vol.40 , pp. 115-120
    • Dahri, S.1    Snoeck, A.2    Reusens-Billen, B.3    Remacle, C.4    Hoet, J.J.5
  • 51
    • 0036203322 scopus 로고    scopus 로고
    • Endocrine pancreas development is altered in foetuses from rats previously showing intra-uterine growth retardation in response to malnutrition
    • Blondeau B, Avril I, Duchene B, Breant B. Endocrine pancreas development is altered in foetuses from rats previously showing intra-uterine growth retardation in response to malnutrition. Diabetologia 45(3), 394-401 (2002).
    • (2002) Diabetologia , vol.45 , Issue.3 , pp. 394-401
    • Blondeau, B.1    Avril, I.2    Duchene, B.3    Breant, B.4
  • 52
    • 0026008824 scopus 로고
    • Fetal and infant growth and impaired glucose tolerance at age 64
    • Hales CN, Barker DJ, Clark PM et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 303(6809), 1019-1022 (1991).
    • (1991) BMJ , vol.303 , Issue.6809 , pp. 1019-1022
    • Hales, C.N.1    Barker, D.J.2    Clark, P.M.3
  • 53
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague CT, Farooqi IS, Whitehead JP et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387(6636), 903-908 (1997).
    • (1997) Nature , vol.387 , Issue.6636 , pp. 903-908
    • Montague, C.T.1    Farooqi, I.S.2    Whitehead, J.P.3
  • 54
    • 0031662163 scopus 로고    scopus 로고
    • A frameshift mutation in human MC4R is associated with a dominant form of obesity
    • Vaisse C, Clement K, Guy-Grand B, Froguel P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat. Genet. 20(2), 113-114 (1998).
    • (1998) Nat. Genet , vol.20 , Issue.2 , pp. 113-114
    • Vaisse, C.1    Clement, K.2    Guy-Grand, B.3    Froguel, P.4
  • 57
    • 0031796690 scopus 로고    scopus 로고
    • The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity
    • Klannemark M, Orho M, Langin D et al. The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity. Diabetologia 41(12), 1516-1522 (1998).
    • (1998) Diabetologia , vol.41 , Issue.12 , pp. 1516-1522
    • Klannemark, M.1    Orho, M.2    Langin, D.3
  • 58
    • 0029843407 scopus 로고    scopus 로고
    • Additive effect of A->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity
    • Clement K, Ruiz J, Cassard-Doulcier AM et al. Additive effect of A->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity. Int. J. Obes. Relat Metab Disord. 20(12), 1062-1066 (1996).
    • (1996) Int. J. Obes. Relat Metab Disord , vol.20 , Issue.12 , pp. 1062-1066
    • Clement, K.1    Ruiz, J.2    Cassard-Doulcier, A.M.3
  • 59
    • 0028795761 scopus 로고
    • Membrane glycoprotein PC-1 and insulin resistance in non-insulindependent diabetes mellitus
    • Maddux BA, Sbraccia P, Kumakura S et al. Membrane glycoprotein PC-1 and insulin resistance in non-insulindependent diabetes mellitus. Nature 373(6513), 448-451 (1995).
    • (1995) Nature , vol.373 , Issue.6513 , pp. 448-451
    • Maddux, B.A.1    Sbraccia, P.2    Kumakura, S.3
  • 60
    • 0032189782 scopus 로고    scopus 로고
    • Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
    • Ristow M, Muller-Wieland D, Pfeiffer A, Krone W, Kahn CR. Obesity associated with a mutation in a genetic regulator of adipocyte differentiation. N. Engl. J. Med. 339(14), 953-959 (1998).
    • (1998) N. Engl. J. Med , vol.339 , Issue.14 , pp. 953-959
    • Ristow, M.1    Muller-Wieland, D.2    Pfeiffer, A.3    Krone, W.4    Kahn, C.R.5
  • 61
    • 0029118510 scopus 로고
    • Insulin resistance: Interactions between obesity and a common variant of insulin receptor substrate-1
    • Clausen JO, Hansen T, Bjorbaek C et al. Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1. Lancet 346(8972), 397-402 (1995).
    • (1995) Lancet , vol.346 , Issue.8972 , pp. 397-402
    • Clausen, J.O.1    Hansen, T.2    Bjorbaek, C.3
  • 62
    • 36549039059 scopus 로고    scopus 로고
    • RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes
    • Kiskinis E, Hallberg M, Christian M et al. RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes. EMBO J. 26(23), 4831-4840 (2007).
    • (2007) EMBO J , vol.26 , Issue.23 , pp. 4831-4840
    • Kiskinis, E.1    Hallberg, M.2    Christian, M.3
  • 64
    • 67650466971 scopus 로고    scopus 로고
    • TNF-alpha promoter methylation as a predictive biomarker for weight-loss response
    • Campion J, Milagro FI, Goyenechea E, Martinez JA. TNF-alpha promoter methylation as a predictive biomarker for weight-loss response. Obesity (Silver. Spring) 17(6), 1293-1297 (2009).
    • (2009) Obesity (Silver. Spring) , vol.17 , Issue.6 , pp. 1293-1297
    • Campion, J.1    Milagro, F.I.2    Goyenechea, E.3    Martinez, J.A.4
  • 65
    • 45549097738 scopus 로고    scopus 로고
    • Development of Type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park JH, Stoffers DA, Nicholls RD, Simmons RA. Development of Type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J. Clin. Invest. 118(6), 2316-2324 (2008).
    • (2008) J. Clin. Invest , vol.118 , Issue.6 , pp. 2316-2324
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 66
    • 41149172495 scopus 로고    scopus 로고
    • Epigenetic regulation of PPARGC1A in human Type 2 diabetic islets and effect on insulin secretion
    • Ling C, Del GS, Lupi R et al. Epigenetic regulation of PPARGC1A in human Type 2 diabetic islets and effect on insulin secretion. Diabetologia 51(4), 615-622 (2008).
    • (2008) Diabetologia , vol.51 , Issue.4 , pp. 615-622
    • Ling, C.1    Del Lupi, G.S.R.2
  • 67
    • 69149087790 scopus 로고    scopus 로고
    • Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
    • Barres R, Osler ME, Yan J et al. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab. 10(3), 189-198 (2009).
    • (2009) Cell Metab , vol.10 , Issue.3 , pp. 189-198
    • Barres, R.1    Osler, M.E.2    Yan, J.3
  • 68
    • 77953190716 scopus 로고    scopus 로고
    • Obesity induced by a pair-fed high fat sucrose diet: Methylation and expression pattern of genes related to energy homeostasis
    • Lomba A, Milagro FI, Garcia-Diaz DF, Marti A, Campion J, Martinez JA. Obesity induced by a pair-fed high fat sucrose diet: methylation and expression pattern of genes related to energy homeostasis. Lipids Health Dis. 9, 60 (2010).
    • (2010) Lipids Health Dis , vol.9 , Issue.60
    • Lomba, A.1    Milagro, F.I.2    Garcia-Diaz, D.F.3    Marti, A.4    Campion, J.5    Martinez, J.A.6
  • 69
    • 77749270389 scopus 로고    scopus 로고
    • Cytosine methylation dysregulation in neonates following intrauterine growth restriction
    • Einstein F, Thompson RF, Bhagat TD et al. Cytosine methylation dysregulation in neonates following intrauterine growth restriction. PLoS ONE 5(1), e8887 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.1 , pp. e8887
    • Einstein, F.1    Thompson, R.F.2    Bhagat, T.D.3
  • 70
    • 84859976315 scopus 로고    scopus 로고
    • Enrichment of (pro)renin receptor promoter with activating histone codes in the kidneys of spontaneously hypertensive rats
    • Lee HA, Lee DY, Lee HJ, Han HS, Kim I. Enrichment of (pro)renin receptor promoter with activating histone codes in the kidneys of spontaneously hypertensive rats. J. Renin. Angiotensin. Aldosterone. Syst. 13(1), 11-18 (2011).
    • (2011) J. Renin. Angiotensin. Aldosterone. Syst , vol.13 , Issue.1 , pp. 11-18
    • Lee, H.A.1    Lee, D.Y.2    Lee, H.J.3    Han, H.S.4    Kim, I.5
  • 71
    • 80054942482 scopus 로고    scopus 로고
    • Methylation of adrenergic beta1 receptor is a potential epigenetic mechanism controlling antihypertensive response to metoprolol
    • Jiang Q, Yuan H, Xing X, Liu J, Huang Z, Du X. Methylation of adrenergic beta1 receptor is a potential epigenetic mechanism controlling antihypertensive response to metoprolol. Indian J. Biochem. Biophys. 48(5), 301-307 (2011).
    • (2011) Indian J. Biochem. Biophys , vol.48 , Issue.5 , pp. 301-307
    • Jiang, Q.1    Yuan, H.2    Xing, X.3    Liu, J.4    Huang, Z.5    Du, X.6
  • 72
    • 81155150148 scopus 로고    scopus 로고
    • Expression of Na+-K+ -2Cl- cotransporter 1 is epigenetically regulated during postnatal development of hypertension
    • Cho HM, Lee HA, Kim HY, Han HS, Kim IK. Expression of Na+-K+ -2Cl- cotransporter 1 is epigenetically regulated during postnatal development of hypertension. Am. J. Hypertens. 24(12), 1286-1293 (2011).
    • (2011) Am. J. Hypertens , vol.24 , Issue.12 , pp. 1286-1293
    • Cho, H.M.1    Lee, H.A.2    Kim, H.Y.3    Han, H.S.4    Kim, I.K.5
  • 73
    • 33847635589 scopus 로고    scopus 로고
    • Expressional and epigenetic alterations of placental serine protease inhibitors: SERPINA3 is a potential marker of preeclampsia
    • Chelbi ST, Mondon F, Jammes H et al. Expressional and epigenetic alterations of placental serine protease inhibitors: SERPINA3 is a potential marker of preeclampsia. Hypertension 49(1), 76-83 (2007).
    • (2007) Hypertension , vol.49 , Issue.1 , pp. 76-83
    • Chelbi, S.T.1    Mondon, F.2    Jammes, H.3
  • 74
    • 77949478630 scopus 로고    scopus 로고
    • Brain renin-angiotensin system: Fetal epigenetic programming by maternal protein restriction during pregnancy
    • Goyal R, Goyal D, Leitzke A, Gheorghe CP, Longo LD. Brain renin-angiotensin system: fetal epigenetic programming by maternal protein restriction during pregnancy. Reprod. Sci. 17(3), 227-238 (2010).
    • (2010) Reprod. Sci , vol.17 , Issue.3 , pp. 227-238
    • Goyal, R.1    Goyal, D.2    Leitzke, A.3    Gheorghe, C.P.4    Longo, L.D.5
  • 75
    • 77955871829 scopus 로고    scopus 로고
    • PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload
    • Lu Z, Xu X, Hu X et al. PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload. Antioxid. Redox. Signal. 13(7), 1011-1022 (2010).
    • (2010) Antioxid. Redox. Signal , vol.13 , Issue.7 , pp. 1011-1022
    • Lu, Z.1    Xu, X.2    Hu, X.3
  • 76
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman KB, Ames BN. The free radical theory of aging matures. Physiol. Rev. 78(2), 547-581 (1998).
    • (1998) Physiol. Rev , vol.78 , Issue.2 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 77
    • 33749234188 scopus 로고    scopus 로고
    • A new paradigm: Manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state
    • Buettner GR, Ng CF, Wang M, Rodgers VG, Schafer FQ. A new paradigm: manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state. Free Radic. Biol. Med. 41(8), 1338-1350 (2006).
    • (2006) Free Radic. Biol. Med , vol.41 , Issue.8 , pp. 1338-1350
    • Buettner, G.R.1    Ng, C.F.2    Wang, M.3    Rodgers, V.G.4    Schafer, F.Q.5
  • 78
    • 0014385432 scopus 로고
    • The catalse-hydrogen peroxide system. Kinetics of catalatic action at high substrate concentrations
    • Jones P, Suggett A. The catalse-hydrogen peroxide system. Kinetics of catalatic action at high substrate concentrations. Biochem. J. 110(4), 617-620 (1968).
    • (1968) Biochem. J , vol.110 , Issue.4 , pp. 617-620
    • Jones, P.1    Suggett, A.2
  • 79
    • 0030022388 scopus 로고    scopus 로고
    • Predominant role of catalase in the disposal of hydrogen peroxide within human erythrocytes
    • Gaetani GF, Ferraris AM, Rolfo M, Mangerini R, Arena S, Kirkman HN. Predominant role of catalase in the disposal of hydrogen peroxide within human erythrocytes. Blood 87(4), 1595-1599 (1996).
    • (1996) Blood , vol.87 , Issue.4 , pp. 1595-1599
    • Gaetani, G.F.1    Ferraris, A.M.2    Rolfo, M.3    Mangerini, R.4    Arena, S.5    Kirkman, H.N.6
  • 80
    • 0014644243 scopus 로고
    • Kinetics of glutathione peroxidase
    • Flohe L, Brand I. Kinetics of glutathione peroxidase. Biochim. Biophys. Acta 191(3), 541-549 (1969).
    • (1969) Biochim. Biophys. Acta , vol.191 , Issue.3 , pp. 541-549
    • Flohe, L.1    Brand, I.2
  • 81
    • 84868554565 scopus 로고    scopus 로고
    • Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4
    • Fazeli G, Stopper H, Schinzel R, Ni CW, Jo H, Schupp N. Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4. Mutagenesis, 27(6), 673-681 (2012).
    • (2012) Mutagenesis , vol.27 , Issue.6 , pp. 673-681
    • Fazeli, G.1    Stopper, H.2    Schinzel, R.3    Ni, C.W.4    Jo, H.5    Schupp, N.6
  • 82
    • 84861330256 scopus 로고    scopus 로고
    • Increased vascular contractility and oxidative stress in beta(2)-adrenoceptor knockout mice: The role of NADPH oxidase
    • Davel AP, Ceravolo GS, Wenceslau CF, Carvalho MH, Brum PC, Rossoni LV. Increased vascular contractility and oxidative stress in beta(2)-adrenoceptor knockout mice: the role of NADPH oxidase. J. Vasc. Res. 49(4), 342-352 (2012).
    • (2012) J. Vasc. Res , vol.49 , Issue.4 , pp. 342-352
    • Davel, A.P.1    Ceravolo, G.S.2    Wenceslau, C.F.3    Carvalho, M.H.4    Brum, P.C.5    Rossoni, L.V.6
  • 83
    • 58149520611 scopus 로고    scopus 로고
    • In vitro effects of beetroot juice and chips on oxidative metabolism and apoptosis in neutrophils from obese individuals
    • Zielinska-Przyjemska M, Olejnik A, Dobrowolska-Zachwieja A, Grajek W. In vitro effects of beetroot juice and chips on oxidative metabolism and apoptosis in neutrophils from obese individuals. Phytother. Res. 23(1), 49-55 (2009).
    • (2009) Phytother. Res , vol.23 , Issue.1 , pp. 49-55
    • Zielinska-Przyjemska, M.1    Olejnik, A.2    Dobrowolska-Zachwieja, A.3    Grajek, W.4
  • 84
    • 66449112021 scopus 로고    scopus 로고
    • Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells
    • Morgan D, Rebelato E, Abdulkader F et al. Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells. Endocrinology 150(5), 2197-2201 (2009).
    • (2009) Endocrinology , vol.150 , Issue.5 , pp. 2197-2201
    • Morgan, D.1    Rebelato, E.2    Abdulkader, F.3
  • 85
    • 0032053707 scopus 로고    scopus 로고
    • Oxygen radicals and signaling
    • Finkel T. Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10(2), 248-253 (1998).
    • (1998) Curr. Opin. Cell Biol , vol.10 , Issue.2 , pp. 248-253
    • Finkel, T.1
  • 86
    • 24744446561 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases as targets of the combined insulinomimetic effects of zinc and oxidants
    • Haase H, Maret W. Protein tyrosine phosphatases as targets of the combined insulinomimetic effects of zinc and oxidants. Biometals 18(4), 333-338 (2005).
    • (2005) Biometals , vol.18 , Issue.4 , pp. 333-338
    • Haase, H.1    Maret, W.2
  • 87
    • 0034633602 scopus 로고    scopus 로고
    • Hydrogen peroxide: A key messenger that modulates protein phosphorylation through cysteine oxidation
    • Rhee SG, Bae YS, Lee SR, Kwon J. Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci. STKE 2000(53), e1 (2000).
    • (2000) Sci. STKE , vol.2000 , Issue.53 , pp. e1
    • Rhee, S.G.1    Bae, Y.S.2    Lee, S.R.3    Kwon, J.4
  • 88
    • 55149107716 scopus 로고    scopus 로고
    • Radical-free biology of oxidative stress
    • Jones DP. Radical-free biology of oxidative stress. Am. J. Physiol Cell Physiol 295(4), C849-C868 (2008).
    • (2008) Am. J. Physiol Cell Physiol , vol.295 , Issue.4 , pp. C849-C868
    • Jones, D.P.1
  • 89
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/ glutathione couple
    • Schafer FQ, Buettner GR. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/ glutathione couple. Free Radic. Biol. Med. 30(11), 1191-1212 (2001).
    • (2001) Free Radic. Biol. Med , vol.30 , Issue.11 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 90
    • 44949249095 scopus 로고    scopus 로고
    • Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome
    • Skalicky J, Muzakova V, Kandar R, Meloun M, Rousar T, Palicka V. Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome. Clin. Chem. Lab Med. 46(4), 499-505 (2008).
    • (2008) Clin. Chem. Lab Med , vol.46 , Issue.4 , pp. 499-505
    • Skalicky, J.1    Muzakova, V.2    Kandar, R.3    Meloun, M.4    Rousar, T.5    Palicka, V.6
  • 91
    • 0033373619 scopus 로고    scopus 로고
    • Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo
    • Mohamed-Ali V, Goodrick S, Bulmer K, Holly JM, Yudkin JS, Coppack SW. Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo. Am. J. Physiol 277(6 Pt 1), E971-E975 (1999).
    • (1999) Am. J. Physiol , vol.277 , Issue.6 , pp. E971-E975
    • Mohamed-Ali, V.1    Goodrick, S.2    Bulmer, K.3    Holly, J.M.4    Yudkin, J.S.5    Coppack, S.W.6
  • 92
    • 0034869253 scopus 로고    scopus 로고
    • Human C-reactive protein: Expression, structure, and function
    • Volanakis JE. Human C-reactive protein: expression, structure, and function. Mol. Immunol. 38(2-3), 189-197 (2001).
    • (2001) Mol. Immunol , vol.38 , Issue.2-3 , pp. 189-197
    • Volanakis, J.E.1
  • 93
    • 0033192573 scopus 로고    scopus 로고
    • Oxidant stress regulation of IL-8 and ICAM-1 gene expression: Differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review)
    • Roebuck KA. Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review). Int. J. Mol. Med. 4(3), 223-230 (1999).
    • (1999) Int. J. Mol. Med , vol.4 , Issue.3 , pp. 223-230
    • Roebuck, K.A.1
  • 94
    • 85030434746 scopus 로고    scopus 로고
    • Increased oxidative stress in obesity and its impact on metabolic syndrome
    • Furukawa S, Fujita T, Shimabukuro M et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114(12), 1752-1761 (2004).
    • (2004) J. Clin. Invest , vol.114 , Issue.12 , pp. 1752-1761
    • Furukawa, S.1    Fujita, T.2    Shimabukuro, M.3
  • 95
    • 79960023572 scopus 로고    scopus 로고
    • The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in highfat- fed rats
    • Tian YF, Hsia TL, Hsieh CH, Huang DW, Chen CH, Hsieh PS. The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in highfat- fed rats. Life Sci. 89(3-4), 107-114 (2011).
    • (2011) Life Sci , vol.89 , Issue.3-4 , pp. 107-114
    • Tian, Y.F.1    Hsia, T.L.2    Hsieh, C.H.3    Huang, D.W.4    Chen, C.H.5    Hsieh, P.S.6
  • 96
    • 83155175390 scopus 로고    scopus 로고
    • Predominant role of obesity/insulin resistance in oxidative stress development
    • Darchivio M, Annuzzi G, Vari R et al. Predominant role of obesity/insulin resistance in oxidative stress development. Eur. J. Clin. Invest 42(1), 70-78 (2012).
    • (2012) Eur. J. Clin. Invest , vol.42 , Issue.1 , pp. 70-78
    • Darchivio, M.1    Annuzzi, G.2    Vari, R.3
  • 98
    • 79960885598 scopus 로고    scopus 로고
    • Dairy attentuates oxidative and inflammatory stress in metabolic syndrome
    • Stancliffe RA, Thorpe T, Zemel MB. Dairy attentuates oxidative and inflammatory stress in metabolic syndrome. Am. J. Clin. Nutr. 94(2), 422-430 (2011).
    • (2011) Am. J. Clin. Nutr , vol.94 , Issue.2 , pp. 422-430
    • Stancliffe, R.A.1    Thorpe, T.2    Zemel, M.B.3
  • 99
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino F, Hishikawa K, Katusic ZS, Luscher TF. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96(1), 25-28 (1997).
    • (1997) Circulation , vol.96 , Issue.1 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Luscher, T.F.4
  • 100
    • 0032958288 scopus 로고    scopus 로고
    • Contributions of polyol pathway to oxidative stress in diabetic cataract
    • Lee AY, Chung SS. Contributions of polyol pathway to oxidative stress in diabetic cataract. FASEB J. 13(1), 23-30 (1999).
    • (1999) FASEB J , vol.13 , Issue.1 , pp. 23-30
    • Lee, A.Y.1    Chung, S.S.2
  • 101
    • 77952316362 scopus 로고    scopus 로고
    • Antioxidant status and lipid peroxidation in diabetic rats under hyperbaric oxygen exposure
    • Matsunami T, Sato Y, Sato T, Yukawa M. Antioxidant status and lipid peroxidation in diabetic rats under hyperbaric oxygen exposure. Physiol Res. 59(1), 97-104 (2010).
    • (2010) Physiol Res , vol.59 , Issue.1 , pp. 97-104
    • Matsunami, T.1    Sato, Y.2    Sato, T.3    Yukawa, M.4
  • 103
    • 0032905015 scopus 로고    scopus 로고
    • In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin e supplementation
    • Davi G, Ciabattoni G, Consoli A et al. In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. Circulation 99(2), 224-229 (1999).
    • (1999) Circulation , vol.99 , Issue.2 , pp. 224-229
    • Davi, G.1    Ciabattoni, G.2    Consoli, A.3
  • 104
    • 78049373400 scopus 로고    scopus 로고
    • Association of dietary AGEs with circulating AGEs, glycated LDL, IL-1alpha and MCP-1 levels in Type 2 diabetic patients
    • Chao PC, Huang CN, Hsu CC, Yin MC, Guo YR. Association of dietary AGEs with circulating AGEs, glycated LDL, IL-1alpha and MCP-1 levels in Type 2 diabetic patients. Eur. J. Nutr. 49(7), 429-434 (2010).
    • (2010) Eur. J. Nutr , vol.49 , Issue.7 , pp. 429-434
    • Chao, P.C.1    Huang, C.N.2    Hsu, C.C.3    Yin, M.C.4    Guo, Y.R.5
  • 105
    • 77951183729 scopus 로고    scopus 로고
    • Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with Type 2 diabetes and effect of metformin
    • Rabbani N, Chittari MV, Bodmer CW, Zehnder D, Ceriello A, Thornalley PJ. Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with Type 2 diabetes and effect of metformin. Diabetes 59(4), 1038-1045 (2010).
    • (2010) Diabetes , vol.59 , Issue.4 , pp. 1038-1045
    • Rabbani, N.1    Chittari, M.V.2    Bodmer, C.W.3    Zehnder, D.4    Ceriello, A.5    Thornalley, P.J.6
  • 106
    • 17544394772 scopus 로고    scopus 로고
    • Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status
    • Vericel E, Januel C, Carreras M, Moulin P, Lagarde M. Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. Diabetes 53(4), 1046-1051 (2004).
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1046-1051
    • Vericel, E.1    Januel, C.2    Carreras, M.3    Moulin, P.4    Lagarde, M.5
  • 107
    • 0036175986 scopus 로고    scopus 로고
    • Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney
    • Chabrashvili T, Tojo A, Onozato ML et al. Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney. Hypertension 39(2), 269-274 (2002).
    • (2002) Hypertension , vol.39 , Issue.2 , pp. 269-274
    • Chabrashvili, T.1    Tojo, A.2    Onozato, M.L.3
  • 108
    • 4444257541 scopus 로고    scopus 로고
    • Reactive oxygen species in hypertension; An update
    • Lassegue B, Griendling KK. Reactive oxygen species in hypertension; an update. Am. J. Hypertens. 17(9), 852-860 (2004).
    • (2004) Am. J. Hypertens , vol.17 , Issue.9 , pp. 852-860
    • Lassegue, B.1    Griendling, K.K.2
  • 109
    • 11144297987 scopus 로고    scopus 로고
    • Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle
    • Weber DS, Rocic P, Mellis AM et al. Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle. Am. J. Physiol Heart Circ. Physiol 288(1), H37-H42 (2005).
    • (2005) Am. J. Physiol Heart Circ. Physiol , vol.288 , Issue.1 , pp. H37-H42
    • Weber, D.S.1    Rocic, P.2    Mellis, A.M.3
  • 110
    • 0031015288 scopus 로고    scopus 로고
    • P22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats
    • Fukui T, Ishizaka N, Rajagopalan S et al. p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. Circ. Res. 80(1), 45-51 (1997).
    • (1997) Circ. Res , vol.80 , Issue.1 , pp. 45-51
    • Fukui, T.1    Ishizaka, N.2    Rajagopalan, S.3
  • 111
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
    • Rajagopalan S, Kurz S, Munzel T et al. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest 97(8), 1916-1923 (1996).
    • (1996) J. Clin. Invest , vol.97 , Issue.8 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3
  • 112
  • 113
    • 0142182739 scopus 로고    scopus 로고
    • Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase
    • Kitiyakara C, Chabrashvili T, Chen Y et al. Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J. Am. Soc. Nephrol. 14(11), 2775-2782 (2003).
    • (2003) J. Am. Soc. Nephrol , vol.14 , Issue.11 , pp. 2775-2782
    • Kitiyakara, C.1    Chabrashvili, T.2    Chen, Y.3
  • 116
    • 0036069786 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase and cardiovascular disease
    • Fukai T, Folz RJ, Landmesser U, Harrison DG. Extracellular superoxide dismutase and cardiovascular disease. Cardiovasc. Res. 55(2), 239-249 (2002).
    • (2002) Cardiovasc. Res , vol.55 , Issue.2 , pp. 239-249
    • Fukai, T.1    Folz, R.J.2    Landmesser, U.3    Harrison, D.G.4
  • 117
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: Animal and human studies
    • Griendling KK, Fitzgerald GA. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 108(17), 2034-2040 (2003).
    • (2003) Circulation , vol.108 , Issue.17 , pp. 2034-2040
    • Griendling, K.K.1    Fitzgerald, G.A.2
  • 118
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 86(5), 494-501 (2000).
    • (2000) Circ. Res , vol.86 , Issue.5 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 119
    • 0032722311 scopus 로고    scopus 로고
    • Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion
    • Wang HQ, Smart RC. Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion. J. Cell Sci. 112(Pt 20), 3497-3506 (1999).
    • (1999) J. Cell Sci , vol.112 , pp. 3497-3506
    • Wang, H.Q.1    Smart, R.C.2
  • 120
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV- 1
    • Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV- 1. EMBO J. 10(8), 2247-2258 (1991).
    • (1991) EMBO J , vol.10 , Issue.8 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 121
    • 34547790677 scopus 로고    scopus 로고
    • Interplay among oxidants, antioxidants, and cytokines in skin disorders: Present status and future considerations
    • Portugal M, Barak V, Ginsburg I, Kohen R. Interplay among oxidants, antioxidants, and cytokines in skin disorders: present status and future considerations. Biomed. Pharmacother. 61(7), 412-422 (2007).
    • (2007) Biomed. Pharmacother , vol.61 , Issue.7 , pp. 412-422
    • Portugal, M.1    Barak, V.2    Ginsburg, I.3    Kohen, R.4
  • 123
    • 84875103455 scopus 로고    scopus 로고
    • Balancing reactive oxygen species in the epigenome: NADPH oxidases as target and perpetrator
    • Hayes P, Knaus UG. Balancing reactive oxygen species in the epigenome: NADPH oxidases as target and perpetrator. Antioxid. Redox. Signal. 18(15), 1937-1945 (2013).
    • (2013) Antioxid. Redox. Signal , vol.18 , Issue.15 , pp. 1937-1945
    • Hayes, P.1    Knaus, U.G.2
  • 124
    • 37149010874 scopus 로고    scopus 로고
    • Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation
    • Campos AC, Molognoni F, Melo FH et al. Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation. Neoplasia. 9(12), 1111-1121 (2007).
    • (2007) Neoplasia , vol.9 , Issue.12 , pp. 1111-1121
    • Campos, A.C.1    Molognoni, F.2    Melo, F.H.3
  • 125
    • 34548140496 scopus 로고    scopus 로고
    • An epigenetic perspective on the free radical theory of development
    • Hitchler MJ, Domann FE. An epigenetic perspective on the free radical theory of development. Free Radic. Biol. Med. 43(7), 1023-1036 (2007).
    • (2007) Free Radic. Biol. Med , vol.43 , Issue.7 , pp. 1023-1036
    • Hitchler, M.J.1    Domann, F.E.2
  • 126
    • 85016326735 scopus 로고    scopus 로고
    • New nucleophilic mechanisms of ros-dependent epigenetic modifications: Comparison of aging and cancer
    • Afanasev I. New nucleophilic mechanisms of ros-dependent epigenetic modifications: comparison of aging and cancer. Aging Dis. 5(1), 52-62 (2014).
    • (2014) Aging Dis , vol.5 , Issue.1 , pp. 52-62
    • Afanasev, I.1
  • 127
    • 84863206202 scopus 로고    scopus 로고
    • Norepinephrine causes epigenetic repression of PKCepsilon gene in rodent hearts by activating Nox1-dependent reactive oxygen species production
    • Xiong F, Xiao D, Zhang L. Norepinephrine causes epigenetic repression of PKCepsilon gene in rodent hearts by activating Nox1-dependent reactive oxygen species production. FASEB J. 26(7), 2753-2763 (2012).
    • (2012) FASEB J , vol.26 , Issue.7 , pp. 2753-2763
    • Xiong, F.1    Xiao, D.2    Zhang, L.3
  • 128
    • 84863116142 scopus 로고    scopus 로고
    • Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
    • Nanduri J, Makarenko V, Reddy VD et al. Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proc. Natl Acad. Sci. USA 109(7), 2515-2520 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.7 , pp. 2515-2520
    • Nanduri, J.1    Makarenko, V.2    Reddy, V.D.3
  • 129
    • 84882656834 scopus 로고    scopus 로고
    • Oxidative stress induces hypomethylation of LINE-1 and hypermethylation of the RUNX3 promoter in a bladder cancer cell line
    • Wongpaiboonwattana W, Tosukhowong P, Dissayabutra T, Mutirangura A, Boonla C. Oxidative stress induces hypomethylation of LINE-1 and hypermethylation of the RUNX3 promoter in a bladder cancer cell line. Asian Pac. J. Cancer Prev. 14(6), 3773-3778 (2013).
    • (2013) Asian Pac. J. Cancer Prev , vol.14 , Issue.6 , pp. 3773-3778
    • Wongpaiboonwattana, W.1    Tosukhowong, P.2    Dissayabutra, T.3    Mutirangura, A.4    Boonla, C.5
  • 130
    • 84878660136 scopus 로고    scopus 로고
    • Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells
    • Zhang R, Kang KA, Kim KC et al. Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells. Gene 524(2), 214-219 (2013).
    • (2013) Gene , vol.524 , Issue.2 , pp. 214-219
    • Zhang, R.1    Kang, K.A.2    Kim, K.C.3
  • 131
    • 84876105336 scopus 로고    scopus 로고
    • Regulation of SOD2 in cancer by histone modifications and CpG methylation: Closing the loop between redox biology and epigenetics
    • Cyr AR, Hitchler MJ, Domann FE. Regulation of SOD2 in cancer by histone modifications and CpG methylation: closing the loop between redox biology and epigenetics. Antioxid. Redox. Signal. 18(15), 1946-1955 (2013).
    • (2013) Antioxid. Redox. Signal , vol.18 , Issue.15 , pp. 1946-1955
    • Cyr, A.R.1    Hitchler, M.J.2    Domann, F.E.3
  • 132
    • 77954083190 scopus 로고    scopus 로고
    • Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: A basis for excessive cell proliferation and a new therapeutic target
    • Archer SL, Marsboom G, Kim GH et al. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation 121(24), 2661-2671 (2010).
    • (2010) Circulation , vol.121 , Issue.24 , pp. 2661-2671
    • Archer, S.L.1    Marsboom, G.2    Kim, G.H.3
  • 133
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones PA, Taylor SM. Cellular differentiation, cytidine analogs and DNA methylation. Cell 20(1), 85-93 (1980).
    • (1980) Cell , vol.20 , Issue.1 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 134
    • 77955238361 scopus 로고    scopus 로고
    • Targeting of 5-aza-2-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme
    • Patel K, Dickson J, Din S, Macleod K, Jodrell D, Ramsahoye B. Targeting of 5-aza-2-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme. Nucleic Acids Res. 38(13), 4313-4324 (2010).
    • (2010) Nucleic Acids Res , vol.38 , Issue.13 , pp. 4313-4324
    • Patel, K.1    Dickson, J.2    Din, S.3    Macleod, K.4    Jodrell, D.5    Ramsahoye, B.6
  • 135
    • 84862828219 scopus 로고    scopus 로고
    • DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity
    • Kim HJ, Kim JH, Chie EK, Young PD, Kim IA, Kim IH. DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity. Radiat. Oncol. 7, 39 (2012).
    • (2012) Radiat. Oncol , vol.7 , Issue.39
    • Kim, H.J.1    Kim, J.H.2    Chie, E.K.3    Young, P.D.4    Kim, I.A.5    Kim, I.H.6
  • 136
    • 25144453808 scopus 로고    scopus 로고
    • Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation
    • Hodge DR, Peng B, Pompeia C et al. Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation. Cancer Biol. Ther. 4(5), 585-592 (2005).
    • (2005) Cancer Biol. Ther , vol.4 , Issue.5 , pp. 585-592
    • Hodge, D.R.1    Peng, B.2    Pompeia, C.3
  • 138
    • 77249099223 scopus 로고    scopus 로고
    • CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression
    • Zelko IN, Mueller MR, Folz RJ. CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression. Free Radic. Biol. Med. 48(7), 895-904 (2010).
    • (2010) Free Radic. Biol. Med , vol.48 , Issue.7 , pp. 895-904
    • Zelko, I.N.1    Mueller, M.R.2    Folz, R.J.3
  • 139
    • 79959838676 scopus 로고    scopus 로고
    • GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response
    • Chen B, Rao X, House MG, Nephew KP, Cullen KJ, Guo Z. GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response. Cancer Lett. 309(1), 37-45 (2011).
    • (2011) Cancer Lett , vol.309 , Issue.1 , pp. 37-45
    • Chen, B.1    Rao, X.2    House, M.G.3    Nephew, K.P.4    Cullen, K.J.5    Guo, Z.6
  • 140
    • 57749090255 scopus 로고    scopus 로고
    • Methylation of polycomb target genes in intestinal cancer is mediated by inflammation
    • Hahn MA, Hahn T, Lee DH et al. Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. Cancer Res. 68(24), 10280-10289 (2008).
    • (2008) Cancer Res , vol.68 , Issue.24 , pp. 10280-10289
    • Hahn, M.A.1    Hahn, T.2    Lee, D.H.3
  • 141
    • 33644874224 scopus 로고    scopus 로고
    • Hypermethylation and loss of expression of glutathione peroxidase-3 in Barretts tumorigenesis
    • Lee OJ, Schneider-Stock R, Mcchesney PA et al. Hypermethylation and loss of expression of glutathione peroxidase-3 in Barretts tumorigenesis. Neoplasia. 7(9), 854-861 (2005).
    • (2005) Neoplasia , vol.7 , Issue.9 , pp. 854-861
    • Lee, O.J.1    Schneider-Stock, R.2    McChesney, P.A.3
  • 142
    • 58249084836 scopus 로고    scopus 로고
    • DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barretts adenocarcinoma
    • Peng DF, Razvi M, Chen H et al. DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barretts adenocarcinoma. Gut 58(1), 5-15 (2009).
    • (2009) Gut , vol.58 , Issue.1 , pp. 5-15
    • Peng, D.F.1    Razvi, M.2    Chen, H.3
  • 143
    • 80053978389 scopus 로고    scopus 로고
    • Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation
    • Khor TO, Huang Y, Wu TY, Shu L, Lee J, Kong AN. Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation. Biochem. Pharmacol. 82(9), 1073-1078 (2011).
    • (2011) Biochem. Pharmacol , vol.82 , Issue.9 , pp. 1073-1078
    • Khor, T.O.1    Huang, Y.2    Wu, T.Y.3    Shu, L.4    Lee, J.5    Kong, A.N.6
  • 144
    • 77952959173 scopus 로고    scopus 로고
    • Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter
    • Min JY, Lim SO, Jung G. Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter. FEBS Lett. 584(11), 2427-2432 (2010).
    • (2010) FEBS Lett , vol.584 , Issue.11 , pp. 2427-2432
    • Min, J.Y.1    Lim, S.O.2    Jung, G.3
  • 145
    • 79955610018 scopus 로고    scopus 로고
    • Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines
    • Karius T, Schnekenburger M, Ghelfi J, Walter J, Dicato M, Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem. Pharmacol. 81(11), 1329-1342 (2011).
    • (2011) Biochem. Pharmacol , vol.81 , Issue.11 , pp. 1329-1342
    • Karius, T.1    Schnekenburger, M.2    Ghelfi, J.3    Walter, J.4    Dicato, M.5    Diederich, M.6
  • 146
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang M, Chen D, Yang CS. Dietary polyphenols may affect DNA methylation. J. Nutr. 137(1 Suppl.), 223S-228S (2007).
    • (2007) J. Nutr , vol.137 , Issue.1 , pp. 223S-228S
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 147
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, Yang CS. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin. Cancer Res. 11(19 Pt 1), 7033-7041 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.19 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 148
    • 48349116871 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds
    • Yang CS, Fang M, Lambert JD, Yan P, Huang TH. Reversal of hypermethylation and reactivation of genes by dietary polyphenolic compounds. Nutr. Rev. 66(Suppl 1), S18-S20 (2008).
    • (2008) Nutr. Rev , vol.66 , pp. S18-S20
    • Yang, C.S.1    Fang, M.2    Lambert, J.D.3    Yan, P.4    Huang, T.H.5
  • 149
    • 56049083256 scopus 로고    scopus 로고
    • Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells
    • Xiang N, Zhao R, Song G, Zhong W. Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. Carcinogenesis 29(11), 2175-2181 (2008).
    • (2008) Carcinogenesis , vol.29 , Issue.11 , pp. 2175-2181
    • Xiang, N.1    Zhao, R.2    Song, G.3    Zhong, W.4
  • 150
    • 84904088448 scopus 로고    scopus 로고
    • Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring
    • Lane M, Mcpherson NO, Fullston T et al. Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring. PLoS ONE 9(7), e100832 (2014).
    • (2014) PLoS ONE , vol.9 , Issue.7 , pp. e100832
    • Lane, M.1    McPherson, N.O.2    Fullston, T.3
  • 151
    • 84862064764 scopus 로고    scopus 로고
    • In utero oxidative stress epigenetically programs antioxidant defense capacity and adulthood diseases
    • Strakovsky RS, Pan YX. In utero oxidative stress epigenetically programs antioxidant defense capacity and adulthood diseases. Antioxid. Redox Signal 17(2), 237-253 (2012).
    • (2012) Antioxid. Redox Signal , vol.17 , Issue.2 , pp. 237-253
    • Strakovsky, R.S.1    Pan, Y.X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.