A MyD88-JAK1-STAT1 complex directly induces SOCS-1 expression in macrophages infected with Group A Streptococcus

Cellular and Molecular Immunology

Volumn 12, Issue 3, 2015, Pages 373-383

  Wu, Jinghua ^a,b   Ma, Cuiqing ^a   Wang, Haixin ^c   Wu, Shuhui ^a   Xue, Gao ^a   Shi, Xinli ^a   Song, Zhang ^a   Wei, Lin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI UNITED UNIVERSITY   (China)

^c Tangshan Hospital of Traditional Chinese Medicine   (China)

Author keywords

Group A Streptococcus; macrophages; SOCS 1; TLR4 MyD88 signaling

Indexed keywords

BETA INTERFERON; JANUS KINASE 1; MONOCLONAL ANTIBODY; MYELOID DIFFERENTIATION FACTOR 88; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOLL LIKE RECEPTOR 4; BLOCKING ANTIBODY; SOCS1 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; COMPLEX FORMATION; CONTROLLED STUDY; GROUP A STREPTOCOCCAL INFECTION; HOST PATHOGEN INTERACTION; MACROPHAGE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; IMMUNE EVASION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PYOGENES; UPREGULATION;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS SP. 'GROUP A';

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; CELL LINE; IMMUNE EVASION; INTERFERON-BETA; JANUS KINASE 1; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; STAT1 TRANSCRIPTION FACTOR; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; SUPPRESSOR OF CYTOKINE SIGNALING 1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 84928884221     PISSN: 16727681     EISSN: 20420226     Source Type: Journal    
DOI: 10.1038/cmi.2014.107     Document Type: Article

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