Activation of TLR3 induces osteogenic responses in human aortic valve interstitial cells through the NF-κB and ERK1/2 pathways

International Journal of Biological Sciences

Volumn 11, Issue 4, 2015, Pages 482-493

  Zhan, Qiong ^a,b   Song, Rui ^a,b   Zeng, Qingchun ^a,b   Yao, Qingzhou ^a,b   Ao, Lihua ^a   Xu, Dingli ^b   Fullerton, David A ^a   Meng, Xianzhong ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Aortic valve interstitial cells; BMP 2; Calcification; TGF 1; TLR3

Indexed keywords

ALKALINE PHOSPHATASE; AORTIC VALVE DISEASE 1; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1;

AORTA VALVE; AORTA VALVE STENOSIS; BONE DEVELOPMENT; CALCINOSIS; CELL CULTURE; CONGENITAL HEART MALFORMATION; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; VALVULAR HEART DISEASE;

ALKALINE PHOSPHATASE; AORTIC VALVE; AORTIC VALVE STENOSIS; BONE MORPHOGENETIC PROTEIN 2; CALCINOSIS; CELLS, CULTURED; HEART DEFECTS, CONGENITAL; HEART VALVE DISEASES; HUMANS; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; OSTEOGENESIS; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84928795226     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.10905     Document Type: Article

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