Circulating nucleic acids as possible damage-associated molecular patterns in different stages of renal failure

Renal Failure

Volumn 32, Issue 4, 2010, Pages 486-492

  Kocić, Gordana ^a   Radenkovic, Sonja ^a   Cvetkovic, Tatjana ^a   Cencic, Avrelija ^b   Carluccio, Francesco ^c   Musovic, Dijana ^a   Nikolić, Goran ^a   Jevtović Stoimenov, Tatjana ^a   Sokolović, Duan ^a   Milojkovic, Boban ^a   Basic, Jelena ^a   Veljkovic, Andrej ^a   Stojanović, Svetlana ^a  

^a UNIVERSITY OF NI   (Serbia)

^b UNIVERSITY OF MARIBOR   (Slovenia)

^c INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

Author keywords

Chronic renal failure; Dialysis; NF B; Signal transduction; Transplantation

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5; NUCLEIC ACID; POLYCYTIDYLIC ACID; RNA; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; HEMODIALYSIS; HUMAN; HUMAN CELL; INFLAMMATION; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MACROPHAGE; MONOCYTE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ISOLATION; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY;

ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; CELL CULTURE TECHNIQUES; CYTOKINES; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MACROPHAGE ACTIVATION; NUCLEIC ACIDS; RENAL DIALYSIS; RNA;

EID: 77952233797     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/08860221003650354     Document Type: Article

References (35)

1. Parmar MS. Chronic renal disease. BMJ. 2002;325(7355):85-90.
2. Rangan G, Wang Y, Harris D. NF-kappaB signalling in chronic kidney disease. Front Biosci. 2009;14:3496-3522.
3. Ma FY, Liu J, Nikolic-Paterson DJ. The role of stress-activated protein kinase signaling in renal pathophysiology. Braz J Med Biol Res. 2009;42(1):29-37.
4. Lotze MT, Zeh HJ, Rubartelli A, et al. The grateful dead: Damage-associated molecular pattern molecules and reduction/ oxidation regulate immunity. Immunol Rev. 2007;220(1): 60-81.
5. Rubartelli A, Lotze MT. Inside, outside, upside down: Damage- associated molecular pattern molecules (DAMPs) and redox. Trends Immunol. 2007;28(10):429-436.
6. Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol. 1994;12:991-1045.
7. Foell D, Wittkowski H, Roth J. Mechanisms of disease: A "DAMP" view of inflammatory arthritis. Nat Clin Pract Rheumatol. 2007;3(7):382-390.
8. Barrat FJ, Meeker T, Gregorio J, et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Environ Monit. 2005;202(8):1131-1139.
9. Navab M, Gharavi N, Watson AD. Inflammation and metabolic disorders. Curr Opin Clin Nutr Metab Care. 2008; 11(4):459-464.
10. Pawar RD, Patole PS, Wörnle M, Anders HJ. Microbial nucleic acids pay a Toll in kidney disease. Am J Physiol Renal Physiol. 2006;291:F509-F516.
11. Mollen KP, Rahul JP, Tsung A, Prince JM, Levy RM, Billiar TR. Emerging paradigm: Toll like receptor 4- sentinel for the detection of tissue damage. Shock. 2006;26(5):430-437.
12. Diebold SS, Kaisho T, Hemmi H, Akira S, Sousa R. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science. 2004;303:1529-1531. (Pubitemid 38314425)
13. Deane AJ, Bolland S. Nucleic acid-sensing TLRs as modifiers of autoimmunity. J Immunol. 2006;177:6573-6578.
14. Moriyama H, Wen L, Abiru N, et al. Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic- polycytidilyc acid) and an insulin self-peptide. Proc Natl Acad Sci U S A. 2002;99:5539-5544.
15. Schein CH. From housekeeper to micro surgeon: The diagnostic and therapeutic potential of ribonucleases. Nature Biotechnol. 1997;15:529-536.
16. Kocic G, Bjelakovic G, Saranac LJ, et al. Altered degradation of circulating nucleic acids and oligonucleotides in diabetic patients. Diabetes Res Clin Pract. 2008;79(2):204-213.
17. Kocic G, Kocic R, Pavlovic R, et al. Possible impact of impaired double-stranded RNA degradation and nitrosative stress on immunoinflammatory cascade in type 2 diabetes. Exp Clin Endocrinol Diabetes. 2009;117:1-6.
18. National Kidney Foundation - K/DOQI. Clinical practice guidelines for chronic kidney disease: Evaluation, classification and stratification. Am J Kidney Dis. 2002;39(Suppl. 1):S1-S266.
19. Cavaluzzi M, Borer P. Revised UV extinction coefficients for nucleoside-5′-monophosphates and unpaired DNA and RNA. Nucleic Acids Res. 2004;32:e1-e13.
20. Reimer T, Brcic M, Schweizer M, Jungi TW. Poly(I:C) and LPS induce distinct IRF3 and NF-kB signaling during type-I IFN and TNF responses in human macrophages. J Leukoc Biol. 2008;83:1249-1257.
21. Gelman AE, Zhang J, Chol Y, Turka LA. Toll-like receptor ligands directly promote activated CD4+T cell survival. J Immunol. 2004;172:6065-6073.
22. Wardle EN. Toll-like receptors and glomerulonephritis. Saudi J Kidney Dis Transpl. 2007;18:159-172.
23. Pascual V, Farkas L, Banchereau J. Systemic lupus erythematosus: All roads lead to type 1 interferons. Curr Opin Immunol. 2006;18:676-682. (Pubitemid 44635182)
24. Lang KS, Recher M, Junt T, et al. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med. 2005;11:138-145.
25. Konda R, Sugimura J, Sohma F, Katagiri T, Nakamura Y, Fujioka T. Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappa B is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure. J Urol. 2008;180(2):481-485.
26. Seimon TA, Wang Y, Han S, et al. Macrophage deficiency of p38a MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. J Clin Invest. 2009;119(4):886-898.
27. Maung AA, Fujimi S, Miller ML, MacConmara MP, Mannick JA, Lederer JA. Enhanced TLR4 reactivity following injury is mediated by increased p38 activation. J Leukoc Biol. 2005;78:565-573.
28. Toshiro K, Hiroki Y, Hiroaki S, Kentaro K, Toshiko T, Noriyuki T. Role of p38 mitogen-activated protein kinase pathway on renal failure in the infant rat after burn injury. Shock. 2004;21(6):535-542.
29. Tsoulfas G, Geller DA. NF-kB in transplantation: Friend or foe? Transpl Infect Dis. 2001;3(4):212-219.
30. Kato H, Takeuchi O, Sato S, et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature. 2006;441:101-105.
31. Yeow WS, Au WC, Lowther WJ, Pitha PM. Downregulation of IRF-3 levels by ribozyme modulates the profile of IFNA subtypes expressed in infected human cells. J Virol. 2001; 75(6):3021-3027.
32. Peters K, Chattopadhyay S, Sen GC. IRF-3 activation by sendai virus infection is required for cellular apoptosis and avoidance of persistence. J Virol. 2008;82(7):3500-3508.
33. Hiscott J. Triggering the innate antiviral response through IRF-3 activation. J Biol Chem. 2007;282(21):15325-15329.
34. Claesson K, Rönnblom L, Alm G, Tufveson G. Antiviral activity appearing in serum of renal transplant recipients. Its possible relation to immunological rejection. Transplantation. 1984; 38(1):32-34.
35. Rostaing L, Modesto A, Baron E, Cisterne JM, Chabannier MH, Durand D. Acute renal failure in kidney transplant patients treated with interferon alpha 2b for chronic hepatitis C. Nephron. 1996;74(3):512-516. (Pubitemid 26364720)