Analysis of high-affinity binding of protein kinase R to double-stranded RNA

Biochemistry

Volumn 51, Issue 44, 2012, Pages 8764-8770

  Husain, Bushra ^a   Mukerji, Ishita ^b   Cole, James L ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b WESLEYAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION MECHANISMS; ANALYTICAL ULTRACENTRIFUGATION; AUTOPHOSPHORYLATION; BINDING DOMAIN; BINDING MODES; BINDING MOTIF; DIRECT INTERACTIONS; DOUBLE-STRANDED RNA; DOUBLE-STRANDED RNA (DSRNA); ENHANCED SENSITIVITY; INNATE IMMUNITY; KINASE DOMAINS; LOW SALT CONCENTRATION; MINIMAL LENGTHS; NANOMOLAR; NON-SPECIFIC BINDING; PROTEIN KINASE; RNA CONCENTRATION; SALT CONCENTRATION; STANDARD MODEL; VIRAL INFECTIONS;

ACTIVATION ANALYSIS; BINDING ENERGY; CENTRIFUGATION; DIMERIZATION; ENZYMES; INTERFERONS; MONOMERS; SODIUM CHLORIDE; STOICHIOMETRY;

RNA;

DOUBLE STRANDED RNA; MONOMER; PROTEIN KINASE R; SODIUM CHLORIDE;

ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLUORESCENCE ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN RNA BINDING; STOICHIOMETRY; ULTRACENTRIFUGATION;

EIF-2 KINASE; ENZYME ACTIVATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RNA, DOUBLE-STRANDED; ULTRACENTRIFUGATION;

EID: 84868561244     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301226h     Document Type: Article

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