A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 40, 2006, Pages 14678-14683

  Vengrenyuk, Yuliya ^a   Carlier, Stéphane ^b   Xanthos, Savvas ^a   Cardoso, Luis ^a   Ganatos, Peter ^a   Virmnani, Renu ^c   Einav, Shmuel ^d,e   Gilchrist, Lane ^a   Weinbaum, Sheldon ^a  

^a City University of New York   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c CVPATH INSTITUTE   (United States)

^d STONY BROOK UNIVERSITY   (United States)

^e TEL AVIV UNIVERSITY   (Israel)

Author keywords

Cellular level calcification; Stress concentration; Thin cap fibroatheroma

Indexed keywords

CALCIUM;

APOPTOSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTOPSY; CALCIFICATION; CELL ACTIVITY; COMPUTER ASSISTED TOMOGRAPHY; CONFOCAL MICROSCOPY; HUMAN; HUMAN TISSUE; HYPOTHESIS; IMAGE ANALYSIS; INTRAVASCULAR ULTRASOUND; MACROPHAGE; MATHEMATICAL MODEL; MICROCOMPUTER; NECROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL COHERENCE TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; STAINING; STRESS; THICKNESS;

ATHEROSCLEROSIS; CALCINOSIS; CARDIOMYOPATHIES; CORONARY VESSELS; HUMANS; INCLUSION BODIES; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; RUPTURE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 33749514279     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0606310103     Document Type: Article

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