RNA pathogenesis via Toll-like receptor-activated inflammation in expanded repeat neurodegenerative diseases

Frontiers in Molecular Neuroscience

Volumn 6, Issue SEP, 2013, Pages

  Richards, Robert I ^a   Samaraweera, Saumya E ^a   van Eyk, Clare L ^a   O'Keefe, Louise V ^a   Suter, Catherine M ^b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

Author keywords

Expanded repeat diseases; Innate inflammation; Neuro degeneration; RNA pathogenesis; Toll like receptor

Indexed keywords

DICER; DOUBLE STRANDED RNA; FRAGILE X MENTAL RETARDATION PROTEIN; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; POLYGLUTAMINE; RIBONUCLEASE H; RNA; RNA BINDING PROTEIN; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR;

ADAR1 GENE; AICARDI GOUTIERES SYNDROME; ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; AUTOPHAGY; CAG REPEAT; CHEMICAL MODIFICATION; CYTOKINE RESPONSE; DEGENERATIVE DISEASE; DNA MODIFICATION; DROSOPHILA; FMR1 GENE; FRAGILE X SYNDROME; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUNTINGTON CHOREA; INNATE IMMUNITY; MOLECULAR RECOGNITION; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PREDICTION; RIBONUCLEIC ACID MODIFICATION; RNA METABOLISM; RNA SEQUENCE; RNA TRANSLATION; RNASEH2B GENE; SAMHD1 GENE; TREX1 GENE;

EID: 84885025223     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2013.00025     Document Type: Article

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