Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of erk1/2 and nuclear factor-κb activation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 7, 2013, Pages 1580-1590

  Zeng, Qingchun ^a,b   Song, Rui ^a,c   Ao, Lihua ^a   Weyant, Michael J ^a   Lee, Joon ^a   Xu, Dingli ^b   Fullerton, David A ^a   Meng, Xianzhong ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b Department of Cardiology   (United States)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Aortic valve; Notch1; Pro osteogenic proteins; Signal transduction; Toll like receptor 4

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JAGGED1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOTCH1 RECEPTOR; TOLL LIKE RECEPTOR 4;

AORTA VALVE; ARTICLE; CELL ISOLATION; CELL STIMULATION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

AORTIC VALVE; NOTCH1; PRO-OSTEOGENIC PROTEINS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

AGED; ALKALINE PHOSPHATASE; AORTIC VALVE; AORTIC VALVE STENOSIS; BONE MORPHOGENETIC PROTEIN 2; CALCINOSIS; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; OSTEOGENESIS; PHOSPHORYLATION; RECEPTOR, NOTCH1; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 4; TRANSFECTION; UP-REGULATION;

EID: 84879085837     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300912     Document Type: Article

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