메뉴 건너뛰기




Volumn 117, Issue 9, 2009, Pages 480-485

Possible impact of impaired double-stranded rna degradation and nitrosative stress on immuno-inflammatory cascade in type 2 diabetes

Author keywords

Bax; Bcl 2; Carbonyl groups; Circulating nucleic acids (CNAs) xanthine oxidase (XO); IRF 3; MDA 5; NF .B; Nitric oxide (NO); Rnase; Type 2 diabetes

Indexed keywords

3 NITROTYROSINE; FRUCTOSAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; NITRATE; NITRITE; PROTEIN BAX; PROTEIN BCL 2; RNA; XANTHINE OXIDASE;

EID: 71049172064     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1202830     Document Type: Article
Times cited : (8)

References (55)
  • 1
    • 39649092297 scopus 로고    scopus 로고
    • Obesity, metabolic syndrome, and type 2 diabetes: Inflammatory basis of glucose metabolic disorders.
    • Pradhan A. Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders. Nutr Rev 2007 65 S152-156
    • (2007) Nutr Rev , vol.65 , pp. 152-156
    • Pradhan, A.1
  • 2
    • 0038691972 scopus 로고    scopus 로고
    • Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes.
    • Duncan BB, Schmidt MI, Pankow JS, et al. Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes. Diabetes 2003 52 1799-1805
    • (2003) Diabetes , vol.52 , pp. 1799-1805
    • Duncan, B.B.1    Schmidt, M.I.2    Pankow, J.S.3
  • 3
    • 34547116858 scopus 로고    scopus 로고
    • Review: Pathogen-associated molecular pattern contamination as putative endogenous ligands of Toll-like receptors.
    • (1)
    • Tsan MF, Gao B. Review: Pathogen-associated molecular pattern contamination as putative endogenous ligands of Toll-like receptors. J Endotox Res 2007 13 (1) 6-14
    • (2007) J Endotox Res , vol.13 , pp. 6-14
    • Tsan, M.F.1    Gao, B.2
  • 4
    • 34447131097 scopus 로고    scopus 로고
    • Mechanisms of disease: A DAMP view of inflammatory arthritis.
    • (7)
    • Foell D, Wittkowski H, Roth J. Mechanisms of disease: a DAMP view of inflammatory arthritis. Nat Clin Pract Rheumatol 2007 3 (7) 382-390
    • (2007) Nat Clin Pract Rheumatol , vol.3 , pp. 382-390
    • Foell, D.1    Wittkowski, H.2    Roth, J.3
  • 5
    • 35748945719 scopus 로고    scopus 로고
    • The grateful dead: Damage-associated molecular pattern molecules and reduction/oxidation regulate immunity.
    • Lotze MT, Zeh HJ, Rubartelli A, et al. The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol Rev 2007 220 (1) 60-81
    • (2007) Immunol Rev , vol.220 , Issue.1 , pp. 60-81
    • Lotze, M.T.1    Zeh, H.J.2    Rubartelli, A.3
  • 6
    • 34548857335 scopus 로고    scopus 로고
    • Inside, outside, upside down: Damage-associated molecular-pattern molecules (DAMPs) and redox.
    • (10)
    • Rubartelli A, Lotze MT. Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox. Trends in Immunology 2007 28 (10) 429-436
    • (2007) Trends in Immunology , vol.28 , pp. 429-436
    • Rubartelli, A.1    Lotze, M.T.2
  • 7
    • 0033515098 scopus 로고    scopus 로고
    • Activation of target tissue immune recognition molecules by double-stranded polynucleotides.
    • Suzuki K, Mori A, Ishi KJ, et al. Activation of target tissue immune recognition molecules by double-stranded polynucleotides. Proc Natl Acad Sci USA 1999 96 2285-2290
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2285-2290
    • Suzuki, K.1    Mori, A.2    Ishi, K.J.3
  • 8
    • 24144459516 scopus 로고    scopus 로고
    • Interferon- as a Mediator of Polyinosinic:polycytidylic acidinduced type 1 diabetes.
    • Devendra D, Jasinski J, Melanitou E, et al. Interferon- as a Mediator of Polyinosinic:polycytidylic acidinduced type 1 diabetes. Diabetes 2005 54 2549-2556
    • (2005) Diabetes , vol.54 , pp. 2549-2556
    • Devendra, D.1    Jasinski, J.2    Melanitou, E.3
  • 9
    • 0028304710 scopus 로고
    • Polyinosinic:polycytidylic acid is a potent activator of endothelial cells.
    • Doukas J, Cutler AH, Mordes JP. Polyinosinic:polycytidylic acid is a potent activator of endothelial cells. Am J Pathol 1994 145 137-147
    • (1994) Am J Pathol , vol.145 , pp. 137-147
    • Doukas, J.1    Cutler, A.H.2    Mordes, J.P.3
  • 10
    • 0031572451 scopus 로고    scopus 로고
    • IFN-gamma inhibits double-stranded RNA-induced E-selectin expression in human endothelial cells.
    • Faruqi TR, DiCorleto PE. IFN-gamma inhibits double-stranded RNA-induced E-selectin expression in human endothelial cells. J Immunol 1997 159 3989-3994
    • (1997) J Immunol , vol.159 , pp. 3989-3994
    • Faruqi, T.R.1    Dicorleto, P.E.2
  • 11
    • 0037117454 scopus 로고    scopus 로고
    • Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidilyc acid) and jan insulin sellf-peptide.
    • Moriyama H, Wen L, Abiru N, et al. Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidilyc acid) and jan insulin sellf-peptide. Proc Natl Acad Sci 2002 99 5539-5544
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 5539-5544
    • Moriyama, H.1    Wen, L.2    Abiru, N.3
  • 12
    • 0021795736 scopus 로고
    • Effect of interferon and double-stranded RNA on ß-cell function in mouse islets of Langerhans.
    • Rhodes CJ, Taylor KW. Effect of interferon and double-stranded RNA on ß-cell function in mouse islets of Langerhans. Biochem J 1985 228 87-94
    • (1985) Biochem J , vol.228 , pp. 87-94
    • Rhodes, C.J.1    Taylor, K.W.2
  • 13
    • 0033617148 scopus 로고    scopus 로고
    • Double-stranded RNA inhibits ß-cell function and induces islet damage by stimulating ß-cell production of nitric oxide.
    • Heitmeier MR, Scarim AL, Corbett JA. Double-stranded RNA inhibits ß-cell function and induces islet damage by stimulating ß-cell production of nitric oxide. J Biol Chem 1999 274 12531-12536
    • (1999) J Biol Chem , vol.274 , pp. 12531-12536
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 14
    • 0035013235 scopus 로고    scopus 로고
    • Double-stranded ribonucleic acid (RNA) Induces ß-cell fas messenger RNA expression and increases cytokine-induced ß-cell apoptosis.
    • Liu D, Darville M, Eizirik DL. Double-stranded ribonucleic acid (RNA) Induces ß-cell fas messenger RNA expression and increases cytokine-induced ß-cell apoptosis. Endocrinology 2001 142 2593-2599
    • (2001) Endocrinology , vol.142 , pp. 2593-2599
    • Liu, D.1    Darville, M.2    Eizirik, D.L.3
  • 15
    • 0035408430 scopus 로고    scopus 로고
    • Mechanisms of ß-Cell death in response to double-stranded (ds) RNA and Interferon- dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis.
    • Scarim AL, Arnush M, Blair LA, et al. Mechanisms of ß-Cell death in response to double-stranded (ds) RNA and Interferon- dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis. Am J Pathol 2001 159 273-283
    • (2001) Am J Pathol , vol.159 , pp. 273-283
    • Scarim, A.L.1    Arnush, M.2    Blair, L.A.3
  • 16
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-meiated recognition of single stranded RNA.
    • Diebold SS, Kaisho T, Hemmi H, et al. Innate antiviral responses by means of TLR7-meiated recognition of single stranded RNA. Science 2004 303 1529-1531
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3
  • 17
    • 0036808798 scopus 로고    scopus 로고
    • Perioperative hyperglycemia is a strong correlate of postoperative infection in type II diabetic patients after coronary artery bypass grafting.
    • Guvener M, Pasaoglu I, Demircin M, et al. Perioperative hyperglycemia is a strong correlate of postoperative infection in type II diabetic patients after coronary artery bypass grafting. Endocr J 2002 49 (5) 531-537
    • (2002) Endocr J , vol.49 , Issue.5 , pp. 531-537
    • Guvener, M.1    Pasaoglu, I.2    Demircin, M.3
  • 18
    • 33744517113 scopus 로고    scopus 로고
    • Seroprevalence of hepatitis C in patients with type 2 diabetes mellitus and non-diabetic on haemodialysis
    • DOI 10.1111/j.1368-5031.2005.00738.x
    • Ocak S, Duran N, Kaya H, et al. Seroprevalence of hepatitis C in patients with type 2 diabetes mellitus and non-diabetic on haemodialysis. Int J Clin Pract 2006 60 (6) 670-674 (Pubitemid 43811646)
    • (2006) International Journal of Clinical Practice , vol.60 , Issue.6 , pp. 670-674
    • Ocak, S.1    Duran, N.2    Kaya, H.3    Emir, I.4
  • 19
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
    • Hiroki K, Osamu T, Shintaro S, et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006 441 (7089) 101-105
    • (2006) Nature , vol.441 , Issue.7089 , pp. 101-105
    • Hiroki, K.1    Osamu, T.2    Shintaro, S.3
  • 20
    • 0037154176 scopus 로고    scopus 로고
    • Mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.
    • Kang D, Gopalkrishnan RV, Wu Q, et al. mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc Natl Acad Sci USA 2002 99 (2) 637-642
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.2 , pp. 637-642
    • Kang, D.1    Gopalkrishnan, R.V.2    Wu, Q.3
  • 21
    • 34447499052 scopus 로고    scopus 로고
    • Triggering the innate antiviral response through IRF-3 Activation.
    • (21)
    • Hiscott J. Triggering the innate antiviral response through IRF-3 Activation. J Biol Chem 2007 282 (21) 15325-15329
    • (2007) J Biol Chem , vol.282 , pp. 15325-15329
    • Hiscott, J.1
  • 22
    • 0035129847 scopus 로고    scopus 로고
    • Downregulation of IRF-3 levels by ribozyme modulates the profile of IFNA subtypes expressed in infected human cells.
    • Yeow WS, Au WC, Lowther WJ, et al. Downregulation of IRF-3 levels by ribozyme modulates the profile of IFNA subtypes expressed in infected human cells. J Virol 2001 75 (6) 3021-3027
    • (2001) J Virol , vol.75 , Issue.6 , pp. 3021-3027
    • Yeow, W.S.1    Au, W.C.2    Lowther, W.J.3
  • 23
    • 33744791510 scopus 로고    scopus 로고
    • Essential role of mda-5 in type i IFN responses to polyriboinosinic: Polyribocytidylic acid and encephalomyocarditis picornavirus.
    • Gitlin L, Barchet W, Gilfillan S, et al. Essential role of mda-5 in type I IFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci USA 2006 103 (22) 8459-8464
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.22 , pp. 8459-8464
    • Gitlin, L.1    Barchet, W.2    Gilfillan, S.3
  • 24
    • 24044504031 scopus 로고    scopus 로고
    • Possible impact of plasma RNase activity on immune dysfunction in juvenile diabetes mellitus.
    • Kocic G, Bjelakovic G, Saranac Lj, et al. Possible impact of plasma RNase activity on immune dysfunction in juvenile diabetes mellitus. Pediatr Diab 2005 6 155-160
    • (2005) Pediatr Diab , vol.6 , pp. 155-160
    • Kocic, G.1    Bjelakovic, G.2    Saranac, L.3
  • 25
    • 38649121491 scopus 로고    scopus 로고
    • Altered degradation of circulating nucleic acids and oligonucleotides in diabetic patients.
    • Kocic G, Bjelakovic G, Saranac Lj, et al. Altered degradation of circulating nucleic acids and oligonucleotides in diabetic patients. Diab Res Clin Pract 2008 79 204-213
    • (2008) Diab Res Clin Pract , vol.79 , pp. 204-213
    • Kocic, G.1    Bjelakovic, G.2    Saranac, L.3
  • 26
  • 27
    • 0023181066 scopus 로고
    • Age-related changes in oxidized proteins.
    • Oliver CN, Ahn B, Moerenman EJ, et al. Age-related changes in oxidized proteins. J Biol Chem 1987 262 5488-5491
    • (1987) J Biol Chem , vol.262 , pp. 5488-5491
    • Oliver, C.N.1    Ahn, B.2    Moerenman, E.J.3
  • 28
    • 0033529262 scopus 로고    scopus 로고
    • Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentartion: PH dependence of carbonyl formation, tyrosine nitration and methionine oxidation.
    • Tien M, Berlett BS, Levine RL, et al. Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentartion: pH dependence of carbonyl formation, tyrosine nitration and methionine oxidation. Proc Natl Acad Sci USA 1999 96 7809-7814
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7809-7814
    • Tien, M.1    Berlett, B.S.2    Levine, R.L.3
  • 29
    • 0027742881 scopus 로고
    • Mechanism of fructosamine assay: Evidence against role of superoxide as intermediate in nitroblue tetrazolium reduction.
    • Baker JR, Zyzak DV, Thorpe SR, et al. Mechanism of fructosamine assay: evidence against role of superoxide as intermediate in nitroblue tetrazolium reduction. Clin Chem 1993 39 2460-2465
    • (1993) Clin Chem , vol.39 , pp. 2460-2465
    • Baker, J.R.1    Zyzak, D.V.2    Thorpe, S.R.3
  • 30
    • 0017401689 scopus 로고
    • Simple micro-assay methods for enzymes of purine metabolism.
    • Kizaki H, Sakurada T. Simple micro-assay methods for enzymes of purine metabolism. J Lab Clin Med 1977 89 1135-1144
    • (1977) J Lab Clin Med , vol.89 , pp. 1135-1144
    • Kizaki, H.1    Sakurada, T.2
  • 31
    • 36849012157 scopus 로고    scopus 로고
    • Effect of monosodium glutamate on apoptosis and Bcl-2/Bax protein level in rat thymocyte culture.
    • Pavlovic V, Cekic S, Kociæ G, et al. Effect of monosodium glutamate on apoptosis and Bcl-2/Bax protein level in rat thymocyte culture. Physiol Res 2007 56 619-626
    • (2007) Physiol Res , vol.56 , pp. 619-626
    • Pavlovic, V.1    Cekic, S.2    Kociæ, G.3
  • 32
    • 33646575616 scopus 로고    scopus 로고
    • Oxidative stress and diabetes-associated complications.
    • (Suppl 1)
    • Ceriello A. Oxidative stress and diabetes-associated complications. Endocr Pract 2006 12 (Suppl 1) 60-62
    • (2006) Endocr Pract , vol.12 , pp. 60-62
    • Ceriello, A.1
  • 33
    • 0042093769 scopus 로고    scopus 로고
    • New insights on oxidative stress and diabetic complications may lead to a causal antioxidant therapy.
    • Ceriello A. New insights on oxidative stress and diabetic complications may lead to a causal antioxidant therapy. Diab Care 2003 26 1589-1596
    • (2003) Diab Care , vol.26 , pp. 1589-1596
    • Ceriello, A.1
  • 34
    • 0034746919 scopus 로고    scopus 로고
    • NF-B: A key role in inflammatory diseases.
    • (1)
    • Tak PP, Gary S, Firestein GS. NF-B: a key role in inflammatory diseases. Clin Invest 2001 107 (1) 7-11
    • (2001) Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Gary, S.2    Firestein, G.S.3
  • 35
    • 0025719538 scopus 로고
    • Synthesis of nitric oxide from l-arginine a recently discovered pathway induced by cytokines with antitumor and antimicrobial activity.
    • Hibbs JB. Synthesis of nitric oxide from l-arginine a recently discovered pathway induced by cytokines with antitumor and antimicrobial activity. Res Immunol 1991 142 565-569
    • (1991) Res Immunol , vol.142 , pp. 565-569
    • Hibbs, J.B.1
  • 36
    • 0025883342 scopus 로고
    • Nitric oxide physiology, pathophysiology, and pharmacology.
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991 43 109-142
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 37
    • 12044250527 scopus 로고
    • The physiological role of nitric oxide.
    • Butler AR, Williams DHL. The physiological role of nitric oxide. J Chem Soc Rev 1993 22 233-241
    • (1993) J Chem Soc Rev , vol.22 , pp. 233-241
    • Butler, A.R.1    Williams, D.H.L.2
  • 38
    • 0029128672 scopus 로고
    • The role of nitric oxide and other endothelium-derived vasoactive substances in vascular disease.
    • Cohen RA. The role of nitric oxide and other endothelium-derived vasoactive substances in vascular disease. Prog Cardiovas Dis 1995 38 105-128
    • (1995) Prog Cardiovas Dis , vol.38 , pp. 105-128
    • Cohen, R.A.1
  • 39
    • 0027481965 scopus 로고
    • The reaction of NO with superoxide Free Radic.
    • Huie RE, Padmaja S. The reaction of NO with superoxide Free Radic. Res Commun 1993 18 195-199
    • (1993) Res Commun , vol.18 , pp. 195-199
    • Huie, R.E.1    Padmaja, S.2
  • 40
    • 0034527379 scopus 로고    scopus 로고
    • Effect of four-week metformin treatment on plasma and erythrocyte antioxidative defense enzymes in newly diagnosed obese patients with type 2 diabetes.
    • Pavlovic D, Kocic R, Kocic G, et al. Effect of four-week metformin treatment on plasma and erythrocyte antioxidative defense enzymes in newly diagnosed obese patients with type 2 diabetes. Diabetes Obes Metab 2000 2 251-256
    • (2000) Diabetes Obes Metab , vol.2 , pp. 251-256
    • Pavlovic, D.1    Kocic, R.2    Kocic, G.3
  • 41
    • 33847671460 scopus 로고    scopus 로고
    • Advanced glycation end products and antioxidant status in type 2 diabetic patients with and without peripheral artery disease.
    • Lapolla A, Piarulli F, Sartore G, et al. Advanced glycation end products and antioxidant status in type 2 diabetic patients with and without peripheral artery disease. Diab Care 2007 30 670-676
    • (2007) Diab Care , vol.30 , pp. 670-676
    • Lapolla, A.1    Piarulli, F.2    Sartore, G.3
  • 42
    • 71049151787 scopus 로고    scopus 로고
    • Nitrosative stress and its relation to paramethers of diabetic control in the early stages of Type 1 diabetes.
    • Kocic G, Bjelakovic G, Pavlovic R, et al. Nitrosative stress and its relation to paramethers of diabetic control in the early stages of Type 1 diabetes. Diab Metab 2003 29 4S210
    • (2003) Diab Metab , vol.29
    • Kocic, G.1    Bjelakovic, G.2    Pavlovic, R.3
  • 43
    • 33845305811 scopus 로고    scopus 로고
    • Oxidative stress in the metabolic syndromeOxidative stress in the metabolic syndrome.
    • Esposito K, Ciotola M, Schisano B, et al. Oxidative stress in the metabolic syndromeOxidative stress in the metabolic syndrome. J Endocrinol Invest 2006 29 791-795
    • (2006) J Endocrinol Invest , vol.29 , pp. 791-795
    • Esposito, K.1    Ciotola, M.2    Schisano, B.3
  • 44
    • 0026586147 scopus 로고
    • S -Nitrosylation of proteins with nitric oxide synthesis and characterization of biologically active compounds.
    • Stamler JS, Simon DI, Osbourne JA, et al. S -Nitrosylation of proteins with nitric oxide synthesis and characterization of biologically active compounds. Proc Natl Acad Sci USA 1992 89 444-448
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 444-448
    • Stamler, J.S.1    Simon, D.I.2    Osbourne, J.A.3
  • 45
    • 0029910407 scopus 로고    scopus 로고
    • Regulation of intracellular xanthine oxidase by endothelial-derived nitric oxide.
    • Lung Cell Mol Physiol 15
    • Cote CG, Yu FS, Zulueta JJ, et al. Regulation of intracellular xanthine oxidase by endothelial-derived nitric oxide. Am J Physiol 1996 271 (Lung Cell Mol Physiol 15) L869-L874
    • (1996) Am J Physiol , vol.271
    • Cote, C.G.1    Yu, F.S.2    Zulueta, J.J.3
  • 46
    • 0029758908 scopus 로고    scopus 로고
    • Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.
    • White CR, darley-Usmar V, Berrington WR, et al. Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits. Proc Natl Acad Sci USA 1996 93 8745-8749
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8745-8749
    • White, C.R.1    Darley-Usmar, V.2    Berrington, W.R.3
  • 47
    • 0037698263 scopus 로고    scopus 로고
    • Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression.
    • Connelly L, Jacobs AT, Palacios-Callender M, et al. Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression. J Biol Chem 2003 278 26480-26487
    • (2003) J Biol Chem , vol.278 , pp. 26480-26487
    • Connelly, L.1    Jacobs, A.T.2    Palacios-Callender, M.3
  • 48
    • 0035869450 scopus 로고    scopus 로고
    • Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide.
    • Connelly L, Palacios-Callender M, Ameixa C, et al. Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide. J Immunol 2001 166 3873-3881
    • (2001) J Immunol , vol.166 , pp. 3873-3881
    • Connelly, L.1    Palacios-Callender, M.2    Ameixa, C.3
  • 49
    • 36749091741 scopus 로고    scopus 로고
    • Nuclear factor-kappa B: From clone to clinic.
    • Ahn KS, Sethi G, Aggarwal BB. Nuclear factor-kappa B: from clone to clinic. Curr Mol Med 2007 7 619-637
    • (2007) Curr Mol Med , vol.7 , pp. 619-637
    • Ahn, K.S.1    Sethi, G.2    Aggarwal, B.B.3
  • 50
    • 46949090949 scopus 로고    scopus 로고
    • Poly(I:C) and LPS induce distinct IRF3 and NF-B signaling during type-I IFN and TNF responses in human macrophages.
    • Reimer T, Brcic M, Schweizer M, et al. Poly(I:C) and LPS induce distinct IRF3 and NF-B signaling during type-I IFN and TNF responses in human macrophages. J Leukocyte Biol 2008 83 1249-1257
    • (2008) J Leukocyte Biol , vol.83 , pp. 1249-1257
    • Reimer, T.1    Brcic, M.2    Schweizer, M.3
  • 51
    • 0036224781 scopus 로고    scopus 로고
    • 1 Xanthine oxidase is involved in free radical production in type 1 diabetes.
    • Desco MC, Miguel Asensi M, Márquez R, et al. 1 Xanthine oxidase is involved in free radical production in type 1 diabetes. Protection by Allopurinol Diabetes 2002 51 1118-1124
    • (2002) Protection by Allopurinol Diabetes , vol.51 , pp. 1118-1124
    • Desco, M.C.1    Miguel Asensi, M.2    Márquez, R.3
  • 52
    • 0021358620 scopus 로고
    • Enhanced xanthine oxidase activity in mice treated with interferon and interferon inducers.
    • Ghezzi P, Bianchi PM, Mantovani A, et al. Enhanced xanthine oxidase activity in mice treated with interferon and interferon inducers. Biochem Biophys Res Commun 1984 119 144-149
    • (1984) Biochem Biophys Res Commun , vol.119 , pp. 144-149
    • Ghezzi, P.1    Bianchi, P.M.2    Mantovani, A.3
  • 53
    • 33644631485 scopus 로고    scopus 로고
    • Therapeutic effects of xanthine oxidase inhibitors: Renaissance half a century after the discovery of allopurinol.
    • Pacher P, Nivorozhkin A, Szabo S. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev 2006 58 87-114
    • (2006) Pharmacol Rev , vol.58 , pp. 87-114
    • Pacher, P.1    Nivorozhkin, A.2    Szabo, S.3
  • 54
    • 47249132062 scopus 로고    scopus 로고
    • Select Paramyxoviral v Proteins Inhibit IRF3 Activation by Acting as Alternative Substrates for Inhibitor of B Kinase (IKKe)/TBK1.
    • Lu LL, Puri M, Horvath CM, et al. Select Paramyxoviral V Proteins Inhibit IRF3 Activation by Acting as Alternative Substrates for Inhibitor of B Kinase (IKKe)/TBK1. J Biol Chem 2008 283 (21) 14269-14276
    • (2008) J Biol Chem , vol.283 , Issue.21 , pp. 14269-14276
    • Lu, L.L.1    Puri, M.2    Horvath, C.M.3
  • 55
    • 36148979683 scopus 로고    scopus 로고
    • Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus.
    • Devaraj SG, Wang N, Chen Z, et al. Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus. J Biol Chem 2007 282 (44) 32208-32221
    • (2007) J Biol Chem , vol.282 , Issue.44 , pp. 32208-32221
    • Devaraj, S.G.1    Wang, N.2    Chen, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.