α7 nicotinic acetylcholine receptor-specific antibody induces inflammation and amyloid β42 accumulation in the mouse brain to impair memory

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Lykhmus, Olena ^a   Voytenko, Larysa ^b   Koval, Lyudmyla ^a   Mykhalskiy, Sergiy ^c   Kholin, Victor ^c   Peschana, Kateryna ^c   Zouridakis, Marios ^d   Tzartos, Socrates ^d   Komisarenko, Sergiy ^a   Skok, Maryna ^a  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

^b BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

^c INSTITUTE OF GERONTOLOGY   (Ukraine)

^d HELLENIC PASTEUR INSTITUTE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA3 NICOTINIC ACETYLCHOLINE RECEPTOR; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR SPECIFIC ANTIBODY; AMYLOID BETA PROTEIN[1-42]; BACTERIUM LIPOPOLYSACCHARIDE; BETA4 NICOTINIC ACETYLCHOLINE RECEPTOR; BUNGAROTOXIN RECEPTOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR BETA2; RECEPTOR ANTIBODY; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; ANTIBODY; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NICOTINIC RECEPTOR ALPHA3BETA4; NICOTINIC RECEPTOR ALPHA4BETA2;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; ASTROCYTE; BIOACCUMULATION; BRAIN TISSUE; C57BL 6 MOUSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPISODIC MEMORY; FEMALE; IMMUNIZATION; MEMORY DISORDER; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; SYMPTOM; ANIMAL; BRAIN; CHEMICALLY INDUCED; DRUG EFFECTS; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; NERVE CELL; PATHOLOGY;

BACTERIA (MICROORGANISMS); MUS;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIBODIES; BRAIN; HUMANS; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MEMORY DISORDERS; MICE; NEURONS; RECEPTORS, NICOTINIC;

EID: 84928791760     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122706     Document Type: Article

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