Antibodies against extracellular domains of alpha4 and alpha7 subunits alter the levels of nicotinic receptors in the mouse brain and affect memory: Possible relevance to Alzheimer's pathology

Journal of Alzheimer's Disease

Volumn 24, Issue 4, 2011, Pages 693-704

  Lykhmus, Olena ^a   Koval, Lyudmyla ^a   Skok, Maryna ^a   Zouridakis, Marios ^b   Zisimopoulou, Paraskevi ^b   Tzartos, Socrates ^b   Tsetlin, Victor ^c   Granon, Sylvie ^d   Changeux, Jean Pierre ^e   Komisarenko, Sergiy ^a   Cloëz Tayarani, Isabelle ^e  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

^b UNIVERSITY OF PATRAS   (Greece)

^c SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^d CNRS   (France)

^e CNRS   (France)

Author keywords

Alzheimer's disease; antibodies; brain; episodic memory; ligand binding; nicotinic acetylcholine receptor

Indexed keywords

ALPHA BUNGAROTOXIN I 125; ALPHA4 INTEGRIN; ALPHA7 INTEGRIN; BACTERIUM LIPOPOLYSACCHARIDE; EPIBATIDINE; NICOTINIC RECEPTOR; ANTIBODY; BUNGAROTOXIN RECEPTOR; CHRNA7 PROTEIN, HUMAN; CHRNA7 PROTEIN, MOUSE; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA4 SUBUNIT; PROTEIN SUBUNIT;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR; BEHAVIOR CHANGE; BINDING AFFINITY; BRAIN FUNCTION; BRAIN MEMBRANE; CAUDATE NUCLEUS; CELL LYSATE; CONTROLLED STUDY; CORPUS STRIATUM; EPISODIC MEMORY; FOREBRAIN; HUMAN; IMMUNIZATION; INTERMETHOD COMPARISON; MALE; MEMORY; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RECOGNITION; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; C57BL MOUSE; COMPARATIVE STUDY; EXTRACELLULAR FLUID; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN SUBUNIT; RABBIT; TRANSGENIC MOUSE;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ALZHEIMER DISEASE; ANIMALS; ANTIBODIES; BRAIN; EXTRACELLULAR FLUID; HUMANS; MALE; MEMORY; MEMORY, EPISODIC; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN SUBUNITS; RABBITS; RECEPTORS, NICOTINIC;

EID: 79959271864     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-101842     Document Type: Article

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