Mice lacking neuronal nicotinic acetylcholine receptor β4-subunit and mice lacking both α5- and β4-subunits are highly resistant to nicotine-induced seizures

Physiological Genomics

Volumn 17, Issue , 2004, Pages 221-229

  Kedmi, Merav ^a   Beaudet, Arthur L ^b   Orr Urtreger, Avi ^a,c  

^a TEL AVIV UNIVERSITY   (Israel)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Knockout mice; Neuronal nicotinic acetylcholine receptor 5 and 4 subunits

Indexed keywords

NICOTINE; NICOTINIC RECEPTOR; NICOTINIC AGENT; NICOTINIC RECEPTOR SUBUNIT ALPHA3; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BETA CHAIN; CONTROLLED STUDY; DOSE RESPONSE; FRONTAL LOBE EPILEPSY; GENE MUTATION; GENOTYPE; HOMOZYGOTE; LATENT PERIOD; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEIZURE; SOUTHERN BLOTTING; STATISTICAL ANALYSIS; WILD TYPE; ANIMAL; BRAIN; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; FEMALE; GENE EXPRESSION; GENETICS; KINETICS; MALE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS; NICOTIANA TABACUM; RODENTIA;

ANIMALS; BRAIN; FEMALE; GENE EXPRESSION; KINETICS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NICOTINE; NICOTINIC AGONISTS; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; SEIZURES;

EID: 3142744679     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00202.2003     Document Type: Article

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