α7 Nicotinic acetylcholine receptor-specific antibody stimulates interleukin-6 production in human astrocytes through p38-dependent pathway

International Immunopharmacology

Volumn 23, Issue 2, 2014, Pages 475-479

  Kalashnyk, Olena ^a   Lykhmus, Olena ^a   Oliinyk, Olena ^a   Komisarenko, Sergiy ^a   Skok, Maryna ^a  

^a PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

Author keywords

Antibodies; Astrocytes; Inflammation; Interleukin 6; scFv antibodies; 7 Nicotinic acetylcholine receptor

Indexed keywords

4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; BACTERIUM LIPOPOLYSACCHARIDE; BUNGAROTOXIN RECEPTOR; CHOLINE; IMMUNOGLOBULIN FC FRAGMENT; INTERLEUKIN 6; RECEPTOR ANTIBODY; RECOMBINANT ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SYNAPTOPHYSIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT;

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INTRACELLULAR SIGNALING; NERVOUS SYSTEM INFLAMMATION; U937 CELL LINE; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; PROTEIN SUBUNIT;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANTIBODIES, MONOCLONAL; ASTROCYTES; CELL LINE; HUMANS; INTERLEUKIN-6; MACROPHAGES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN SUBUNITS;

EID: 84912085482     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.09.022     Document Type: Article

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37. L. Koval, O. Lykhmus, O. This work was supported by the Research Programme of Ukrainian Academy of Sciences "Fundamental bases of molecular and cellular biotechnologies" (2010-2014).