ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer

Oncotarget

Volumn 6, Issue 11, 2015, Pages 9173-9188

  Bill, Anke ^a   Gutierrez, Abraham ^a   Kulkarni, Sucheta ^b   Kemp, Carolyn ^b   Bonenfant, Debora ^c   Voshol, Hans ^c   Duvvuri, Umamaheswar ^b,d   Alex Gaither, L ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Biomarker; Calcium activated chloride channel; EGFR targeted therapy; Epidermal growth factor receptor (EGFR); Protein protein interaction

Indexed keywords

6 [4 (4 ETHYL 1 PIPERAZINYLMETHYL)PHENYL] 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; CALCIUM ACTIVATED CHLORIDE CHANNEL; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; LAPATINIB; PROTEIN ANO1; PROTEIN TMEM16A; UNCLASSIFIED DRUG; ANO1 PROTEIN, HUMAN; CD98 ANTIGEN; CHLORIDE CHANNEL; EGFR PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE; SLC3A2 PROTEIN, HUMAN; SMALL INTERFERING RNA; TUMOR PROTEIN;

ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; CELL VIABILITY; COLONY FORMATION; DRUG RESISTANCE; DRUG SENSITIVITY; GENE AMPLIFICATION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MUTANT; PLASMID; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA CELL LINE; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; GENETICS; HEAD AND NECK TUMOR; HEK293 CELL LINE; METABOLISM; MUTATION; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; RNA INTERFERENCE; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

ANTIGENS, CD98 HEAVY CHAIN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CHLORIDE CHANNELS; HEAD AND NECK NEOPLASMS; HEK293 CELLS; HUMANS; MULTIPROTEIN COMPLEXES; MUTATION; NEOPLASM PROTEINS; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84928739991     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3277     Document Type: Article

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